Pathophysiology of male sexual dysfunction in multiple sclerosis

Sexuality and Disability

Volumn 14, Issue 1, 1996, Pages 41-55

  Betts, Christopher D ^a,b  

^a MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

impotence; multiple sclerosis; somatosensory evoked potentials

Indexed keywords

BLADDER FUNCTION; EJACULATION; ENDOCRINE FUNCTION; EVOKED SOMATOSENSORY RESPONSE; HUMAN; HYPERREFLEXIA; IMPOTENCE; MALE; MALE SEXUAL DYSFUNCTION; MORBIDITY; MULTIPLE SCLEROSIS; NEUROPHYSIOLOGY; PATHOPHYSIOLOGY; PENIS ERECTION; REVIEW;

EID: 0029968323     PISSN: 01461044     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02590617     Document Type: Review

References (54)

1. Sachs B, Freidman ED: The general symptoms of multiple sclerosis and the mode of development of the symptoms of multiple sclerosis. Assoc Res Nerv Ment Dis 2:49-55, 1921.
2. Muller R: Studies on disseminated multiple sclerosis. Acta Medica Scandinavica. suppl No 222. 67-71, 1949.
3. Carter S, Sciarra D, Merritt HH: The course of multiple sclerosis as determined by autopsy proven cases. Res Publ Ass Nerv Ment 28:471-509, 1950.
4. Ivers RR, Goldstein NP: Multiple sclerosis: A current appraisal of symptoms and signs. Proc Mayo Clinic 38:457-466, 1963.
5. Miller H, Simpson CA, Yeates WF: Bladder dysfunction in multiple sclerosis. BMJ 1:1265-1269, 1965.
6. Vas CJ: Sexual impotence and some autonomic disturbances in men with multiple sclerosis. Acta Neurologica Scandinavica 45:166-184, 1969.
7. Lilius HG, Valtonen EJ, Wikstrom J: Sexual problems in patients suffering from multiple sclerosis. Scand J Soc Med 4:41-44, 1976.
8. Minderhoud JM, Leehuis JG, Kremer J, Laban E, Smits PM: Sexual disturbances arising from multiple sclerosis. Acta Neurologica Scandinavica 76:299-306, 1984.
9. Valleroy ML, Kraft GK: Sexual dysfunction in multiple sclerosis. Arch Physical Med Rehab 65:125-128, 1984.
10. Langworthy OR: Disturbances of micturition associated with disseminated sclerosis. J Nerv Ment Dis 88:760-770, 1938.
11. Bradley WE, Logothetis JL, Timm GW: Cystometric and sphincter abnormalities in multiple sclerosis. Neurology 23:1131-1139, 1973.
12. Andersen JT, Bradley WE: Abnormalities of detrusor and sphincter function in multiple sclerosis. Brit J Urol 48:193-198, 1976.
13. Bradley WE: Urinary bladder dysfunction in multiple sclerosis. Neurology 28:52-58, 1978.
14. Summers JL: Neurogenic bladder in women with multiple sclerosis. J Urol 120:555-556, 1978.
15. Schoenburg HW, Gutrich J, Banno J: Urodynamic patterns in multiple sclerosis. J Urol 122:648-650, 1979.
16. Piazza DH, Diokno AC: Review of neurogenic bladder in multiple sclerosis. Urology 14:33-35, 1979.
17. Blaivas JG, Bhimani G, Labib KB: Vesicourethral dysfunction in multiple sclerosis. J Urol 122:342-347, 1979.
18. Philp T, Read DJ, Higson RH: The urodynamic characteristics of multiple sclerosis. Br J Urol 53:672-675, 1981.
19. Goldstein I, Siroky MB, Sax S, Krane RJ: Neurourologic abnormalities in multiple sclerosis. J Urol 128:541-545, 1982.
20. Van Poppel H, Vereecken RL, Leruitte A: Neuro-muscular dysfunction of the lower urinary tract in multiple sclerosis. Paraplegia 21:374-379, 1983.
21. Awad SA, Gajewski JB, Sogbein SK, Murray TJ, Field CA: Relationship between neurological and urological status in patients with multiple sclerosis. J Urol 132:499-502, 1984.
22. Hassouna M, Lebel M, Elhilali M. Neurourologic correlation in multiple sclerosis. Neurourology and urodynamics 3:73-77, 1984.
23. Petersen T, Pedersen E: Neurourodynamic evaluation of voiding dysfunction in multiple sclerosis. Acta Neurol Scand 69:402-411, 1984.
24. McGuire EJ, Savastano JA. Urodynamic findings and longterm outcome management of patients with multiple sclerosis induced lower urinary tract dysfunction. J Urol 132:713-715, 1984.
25. Gonor SE, Carroll DJ, Metcalfe JB: Vesical dysfunction in multiple scelerosis. Urology 25: 429-431, 1985.
26. Weinstein MS, Cardenas DD, O'Shaughnessy EJ, Catanzaro ML: Carbon dioxide cystometry and postural changes in patients with multiple sclerosis. Arch Phys Med Rehabil 69:923-927, 1988.
27. Betts CD, D'Mellow MT, Fowler CJ: Urinary symptoms and the neurological features of bladder dysfunction in multiple sclerosis. J Neurol Neurosurg Psychiat 56:245-250, 1993.
28. Kirkeby HJ, Poulsen EU, Petersen T, Dorup J: Erectile dysfunction in multiple sclerosis. Neurology 38:1366-1371, 1988.
29. Betts CD, Jones SJ, Fowler CG, Fowler CJ: Erectile dysfunction in multiple sclerosis: Associated neurological and neurophysiological deficits, and treatment of the condition. Brain 117:1303-1310, 1994.
30. de Groat WC, Steers WD: Neuroanatomy and Neurophysiology of penile erection. In Contemporary Management of Impotence and Infertility, EA Tanagho, TF Lue and RD McLure (eds). Baltimore, Williams & Wilkins, 1988, pp 3-27.
31. Brindley GS: Impotence and ejaculatory failure. In Handbook of neurology, DN Rushton (ed). New York, Marcel Dekker, 1994, pp 329-348.
32. Eckhard C: Untersuchungen uber die Erection des Penis beim Hunde. Bietr Anat Physiol 3: 123-166, 1863
33. Talbot HS: A report on sexual function in paraplegics. J. Urol. 61:265-270, 1949.
34. Bors E, Comarr AE: Neurological disturbances in sexual function with special reference to 529 patients with spinal cord injuries. Urol Surv 10: 191-222, 1960.
35. Brindley GS: Pathophysiology of erection and ejaculation. In Textbook of Genito-Urinary Surgery, H.N. Whitfield and W.F. Hendry (eds). Edinburgh, Churchill Livingstone, 1985, pp. 1083-1094.
36. Walsh WC, Donker PD: Impotence following radical prostatectomy; insight into etiology and prevention. J. Urol. 128:492-497, 1982.
37. Burnstock G: The changing face of autonomic neurotransmission. Acta Physiol. Scand 126: 67-91, 1986.
38. Hyndman OR, Wolkin J: Anterior cordotomy. Further observations on the physiological results and the optimum manner of performance. Arch Neurol Psych 50:129-148, 1943.
39. Kahn EA, Peet MM: The technique of anterolateral cordotomy. J Neurosurg 5:276-283, 1948.
40. MacLean PD, Denniston RH, Dua S: Further studies on cerebral representation of penile erection: caudal thalamus, midbrain and pons. J. Neuophysiol. 26:273-293, 1963.
41. Brindley GS: Reflex ejaculation under vibratory stimulation in paraplegic men. Paraplegia 19: 300-303, 1981.
42. Rushton DN: Sexual and sphincter dysfunction. In Neurology in Clinical Practice, W.G. Bradley, R.B. Daroff, G.M. Fernichel and C.D. Marsden (eds). Boston, Butterworth-Heinemann. 1991, pp. 381-391.
43. Kurtzke JF: Rating neurological impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology (NY) 33:1444-1452, 1983.
44. Cartlidge NEF: Autonomic function in multiple sclerosis. Brain 95:661-664, 1972.
45. Fowler CJ, Betts CD: Clinical value of electrophysiological investigations of patients with urinary symptoms. In Urodynamics: Principles, Practice and Application. Second Edition A.R. Mundy, T.P. Stephenson and A.J. Wein (eds). Edinburgh, Churchill Livingstone. 1994. pp 165-181.
46. Pickard RS, Powell PH, Schofield IS: The clinical application of dorsal penile nerve cerebral-evoked response recording in the investigation of impotence. Brit J Urol 74:231-235, 1994.
47. Haldeman S, Bradley WE, Bhatia N: Evoked responses from the pudendal nerve. J Urol 128: 974-980, 1982.
48. Eretkin C, Akyurekli O, Gurses AN, Turget H: The value of somatosensory-evoked potentials and bulbocavernosus reflex in patients with impotence. Acta Neurol Scand 71:48-53, 1985.
49. Herman CW, Weinberg HJ, Brown J: Testing for neurogenic impotence: a challenge. Urology 27:318-321, 1986.
50. Tackmann W, Porst H, van Ahlen H: Bulbocavemosus reflex latencies and somatosensory evoked potentials after pudendal nerve stimulation in the diagnosis of impotence. J Neurol 235:219-225, 1988.
51. Ganzer H, Madersbacher H, Rumpl E: Cortical evoked potentials by stimulation of the vesicourethral: clinical value and neurophysiological considerations. J Urol 146:118-123, 1991.
52. Taylor MC, Bradley WE, Bhatia N, Glick M, Haldeman S: The conus demyelination syndrome in multiple sclerosis. Acta Neurol Scand 69:80-89:1984.
53. Ron MA, Logsdail SJ: Psychiatric morbidity in multiple sclerosis: a clinical and MRI study. Psychol Med 19:887-895:1989.
54. Thompson AJ, McDonald WI: Multiple Sclerosis and its pathophysiology. In Diseases of the Nervous System: Clinical Neurobiology, 2nd Edition, AK Asbury, GM McKhann, WI McDonald (eds). Philadelphia, WB Saunders, 1992, pp 1209-1228.