Elimination of Introns at the Drosophila suppressor-of-forked Locus by P-Element-Mediated Gene Conversion Shows That an RNA Lacking a Stop Codon is Dispensable

Genetics

Volumn 143, Issue 1, 1996, Pages 345-351

  Williams, Carol J ^a   O'Hare, Kevin ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL VIABILITY; CHROMOSOME BREAKAGE; DROSOPHILA MELANOGASTER; GENE CONVERSION; GENE LOCUS; GENETIC TRANSFORMATION; INTRON; NONHUMAN; PHENOTYPE; POLYADENYLATION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STOP CODON; X CHROMOSOME;

EID: 0029968185     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1093/genetics/143.1.345     Document Type: Article

References (33)

1. BANKIER,A.T., and B. G. BARRELL, 1983 pp. 1-34 in Techniques in Lije Sciences. Nucleic Acid Biochemistty, Vol B5, edited byR. A. FLAVELI..Elsevier Scientific Publishers Ltd., Limerick, Ireland.
2. ENGELS,W. R.,D. M. JOHNSON~CHLITZ, W.B. EGGLESTONand J. SVED,1990 Highfrequency P element loss in Drosophila is homolog dependent. Cell 62: 515-525.
3. ENGEIS,W.R.,C.R.PRESTON and D. M. JOHNSON-SCHLITZ, 1994 Long range cis preference in DNA homology search extending over the lengthof a Drosophila chromosome. Science263: 1623-1625.
4. FLRBERG,E. A.,J. W. MAHAFFEY, B. J. BONDand N. DAVIDSON, 1983 Transcripts of the six Drosophilaactin genes accumulate in a stage and tissuespecific manner. Cell 33: 115-123.
5. GI.OOR,G. B., N. A.NASSIF, D. M. JOHNSON-SCHLITZ, C. R. PRESTON and W. R. ENGEIS,1991 Targetedgenereplacementin Drosophila via P element-induced gap repair. Science 253: 1110-1117.
6. HOOVER, K. R,A.J. CHIENand V. G. CORCES, 1993 Effects of transposable elements o n the expression of the forked gene of Drosophila mlanogaster. Genetics 135: 507-526.
7. JOHNSON~CHLITZ, D.M., and W. R. ENGEIS,1993 P element induced interallelic gene conversion of insertions and deletions in Drosophila mlanogaster. Mol. Cell. Biol. 13: 7006-7018.
8. KLEMENZ, R., U. WEBERand W.J. GEHRING, 1987 The whitegene as a marker ina new Pelement vector for genetransfer in Drosophila. Nucleic Acids Res. 15: 3947-3959.
9. LANKENAU, D.-H., 1995 Genetics of genetics in Drosophila: P elements serving the study of homologous recombination,gene conversion and targeting. Chromosoma 103: 659-668.
10. LEVIS,R., P. M. BINGHAMand G. M. RUBIN,1982 Physical map of the white locus of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 79: 564-568.
11. LINDSLEY, D.L., and G.G. ZIMM,1992 The Genome of Drosophila melanogaster. Academic Press, San Diego, CA.
12. IMANN, K. P., E. A.WEIS andJ. R. NEVINS, 1993 Alternative poly(A) site utilization during adenovirus infection coincides with a decrease inthe activity of a poly(A) siteprocessingfactor. Mol. Cell. Biol. 13: 2411-2419.
13. MAYER, S. A., and C. L. DIECKMANN, 1991 Yeast CBPl mRNA 3‘end formation is regulated during the induction of mitochondrial function. Mol. Cell. BIOI. 11: 813-821.
14. MINVIELLE-SEBASTIA, L.,P. J. PREKERand W. KELLER, 1994 RNA14 and RNA15 proteins ascomponents of a yeast pre-mRNA 3‘end processing factor. Science 266 1702-1706.
15. MINVIEI.I.E~EBASTIA, L., L. B. WINSOR,N. BONNEAUDand F. LACROUTE, 1991 Mutations in the yeast RNA14 and RNA15 genes result in an abnormal decay rate: sequence analysis reveals an RNA binding domain in the RNA15 protein. Mol. Cell. Biol. 11: 3075-3087.
16. MITCHEISON, A., M. SIMONELIG, C.WILLIAMSand K. O’HARE,1993 Homology with SaccharomycescereuisiaeRNA14 suggests that phenotypic suppression in Dmsophila melanogasterby suppressor offorked occurs at the level of RNA stability. Genes Dev. 7: 241-249.
17. MIITELMEIER, T. M., and C.L. DIECKMANN, 1993 In vivo analysisof sequences necessary for CBPldependent accumulation of cytochrome4 transcripts in yeast mitochondria. Mol. Cell. Biol. 175 4203-4213.
18. NASSIF,N., J. PENNEY, S. PAI.,W.R. ENGELSand G. B. GLOOR,1994 Efficient copying of non-homologoussequences from ectopic sites by Pelement-induced gap repair. Mol. Cell. Biol. 14: 1613-1625.
19. PARKHURST, S. M., andV. G.CORCES, 1985 fwkd, gypsysand suppressors. Cell 41: 429-437.
20. &o,D. C., and G. M. RUBIN,1988 Identification and purification of a Drosophila protein that binds to the terminal 31-base pair repeats of the Ptransposable element. Proc. Natl. Acad. Sci. USA 85: 8929-8933.
21. ROBERTSON, H. M,, C.R.PRESTON,R.W. PHILLIS, D.M. JOHNSON-SCHLITZ, W. K. BENZet al., 1988 A stable source of P element transposase in Drosophilamelanogaster. Genetics 118: 461-470.
22. RUDIN,N., and J. E.HABER, 1988 Efficient repair of HO-induced chromosomal breaks in Saccharomycescereuisiae by recombination between flankinghomologoussequences. Mol. Cell. Biol. 8: 3918-3928.
23. SALZ,H. R,T. W. KLINE and P. SCHEDL, 1987 Functional changes associated with structural alterations induced by mobilisation of a Pelement inserted in the Sex-lethalgene ofDrosophila. Genetics 117: 221-231.
24. SAMBROOK, J., E. F. FRITSCH and T. MANIATIS, 1989 Molecular CLoning: A LaboratolyManual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
25. SCHALET, A,, and G. LEFEVRE, 1973 The localisation of ‘ordinary’ sex-linked genes in section 20 of the polytene Xchromosome of Drosophila melanogaster. Chromosoma 44:183-202.
26. SIMONELIG, M., K. ELLIOTT, A. MITCHEISON and K. O’HARE, 1996 Inter-allelic complementation at the s u f @. m roffolked locus of Drosophila reveals complementation between suppressor of forked proteins mutated in different regions. Genetics 142 1225-1235.
27. STAVELEY, B. E., T. R HESLIP,R.B. HODGETTS and J. B.BEI.I., 1995 Protected P element termini suggest a role for inverted repeat binding protein intransposase induced gaprepair. Genetics 139: 1321-1329.
28. TAKAGAKI, Y., and J. L. MANLEY, 1994 A polyadenylation factor subunit is thehumanhomolog of the Drosophilasuppressor of forked protein. Nature 372: 471-474.
29. TAKAGAKI, Y.,J. L MANLEY, C. C.MACDONALD, J.WILUSZand T. SHENK, 1990 A multisubunitfactor, CstF is requiredfor polyadenylation of mammalian pre-mRNAs. Genes Dev. 4: 2112-2120.
30. TALBERT, P. B., C. D. S. LECIELand S. HENIKOFF 1994 Modification of the Drosophila heterochromatic mutation browdominant by linkage alterations. Genetics 136: 559-571.
31. VOEI.KER, R. A., A. L.GREENLEAF,H. GWRKOVICS, G. B. WISEIX, S.-M. HUANGet al., 1984 Frequent imprecise excision among reversions of a Pelement caused lethal mutation in Drosophila. Genetics 107: 279-294.
32. WILI.IAMS, J. E., S. S. PAPPUand J. B. BELL,1988 Molecular analysis of hybrid dysgenesis induced derivatives of a P element allele at the vglocus. Mol. Cell. Biol. 8: 1489-1497.
33. WHITTINGHILL, M., 1937 New mutants: report ofM. Whittinghill. Dros. Inf. Sew. 8: 11.