Structure of the human CD97 gene: Exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily

Genomics

Volumn 32, Issue 1, 1996, Pages 144-147

  Hamann, Jörg ^a,c   Hartmann, Enno ^b   Van Lier, René A W ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c CENTRAL LABORATORY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HORMONE RECEPTOR; OLIGONUCLEOTIDE; RECEPTOR SUBTYPE; SECRETIN;

AMINO ACID SEQUENCE; ARTICLE; CHROMOSOME 19P; DNA LIBRARY; DNA SEQUENCE; EVOLUTION; EXON; GENE STRUCTURE; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SKIN FIBROBLAST;

EID: 0029968118     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0092     Document Type: Article

References (18)

1. Baldwin, J. M. (1993). The probable arrangement of the helices in G protein-coupled receptors. EMBO J. 12: 1693-1703.
2. Baud, V., Chissoe, S. L., Viegas-Pequignot, E., Diriong, S., N'Guyen, V. C., Roe, B. A., and Lipinski, M. (1995). EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments. Genomics 26: 334-344.
3. Campbell, I. D., and Bork, P. (1993). Epidermal growth factor-like domains. Curr. Opin. Struct. Biol. 3: 385-392.
4. Dohlman, H. G., Thorner, J., Caron, M. G., and Lefkowitz, R. J. (1991). Model systems for the study of seven-transmembrane-segment receptors. Annu. Rev. Biochem. 60: 653-688.
5. Doolittle, R. F. (1992). Reconstructing history with amino acid sequences. Protein Sci. 1: 191-200.
6. Eichler, W., Aust, G., and Hamann, D. (1994). Characterization of an early activation-dependent antigen on lymphocytes defined by the monoclonal antibody BL-Ac(F2). Scand. J. Immunol. 39: 111-115.
7. Hamann, J., Eichler, W., Hamann, D., Kerstens, H. M. J., Poddighe, P. J., Hoovers, J. M. N., Hartmann, E., Strauss, M., and van Lier, R. A. W. (1995). Expression cloning and chromosomal mapping of the leucocyte activation antigen CD97, a new sevenspan transmembrane molecule of the secretin receptor superfamily with an unusual extracellular domain. J. Immunol. 155: 1942-1950.
8. Ishihara, T., Nakamura, S., Kaziro, Y., Takahashi, T., Takahashi, K., and Nagata, S. (1991). Molecular cloning and expression of a cDNA encoding the secretin receptor. EMBO J. 10: 1635-1641.
9. Kong, X.-F., Schipani, E., Lanske, B., Joun, H., Karperien, M., Defize, L. H. K., Jüppner, H., Potts, J. T., Segre, G. V., Kronenberg, H. M., and Abou-Samra, A. B. (1994). The rat, mouse and human genes encoding the receptor for parathyroid hormone and parathyroid hormone-related peptide are highly homologous. Biochem. Biophys. Res. Commun. 200: 1290-1299.
10. Lin, S. C., Lin, C. R., Gukovsky, I., Lusis, A. J., Sawchenko, P. E., and Rosenfeld, M. G. (1993). Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature 364: 208-213.
11. Lok, S., Kuijper, J. L., Jelinek, L. J., Kramer, J. M., Whitmore, T. E., Sprecher, C. A., Mathewes, S., Grant, F. J., Biggs, S. H., Rosenberg, G. B., et al. (1994). The human glucagon receptor encoding gene: Structure, cDNA sequence and chromosomal localization. Gene 140: 203-209.
12. Maget, B., Tastenoy, M., and Svoboda, M. (1994). Sequencing of eleven introns in genomic DNA encoding rat glucagon receptor and multiple alternative splicing of its mRNA. FEBS Lett. 351: 271-275.
13. McCuaig, K. A., Clarke, J. C., and White, J. H. (1994). Molecular cloning of the gene encoding the mouse parathyroid hormone/ parathyroid hormone-related peptide receptor. Proc. Natl. Acad. Sci. USA 91: 5051-5055.
14. Patthy, L. (1994). Introns and exons. Curr. Opin. Struct. Biol. 4: 383-392.
15. 2+-binding epidermal growth factor-like domain: Its role in protein-protein interactions. Cell 82: 131-141.
16. Segre, G. V., and Goldring, S. R. (1993). Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family. Trends Endocrinol. Metab. 4: 309-314.
17. Sreedharan, S. P., Huang, J. X., Cheung, M. C., and Goetzl, E. J. (1995). Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene. Proc. Natl. Acad. Sci. USA 92: 2939-2943.
18. Zolnierowicz, S., Cron, P., Solinas-Toldo, S., Fries, R., Lin, H. Y., and Hemmings, B. A. (1994). Isolation, characterization, and chromosomal localization of the porcine calcitonin receptor gene. Identification of two variants of the receptor generated by alternative splicing. J. Biol. Chem. 269: 19530-19538.