MIB-1 and involucrin expression in laryngeal squamous carcinoma: The relationship to host and tumour factors and survival

Clinical Otolaryngology and Allied Sciences

Volumn 21, Issue 5, 1996, Pages 429-438

  Roland, N J ^b   Rowley, H ^b   Scraggs, M ^b   Johnson, P ^b   Jones, A S ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b NONE

Author keywords

Carcinoma of the larynx; Cell proliferation; Head and neck squamous carcinoma; Histological markers; Involucrin MIB 1; Ki67; Prognosis; Tumour differentiation

Indexed keywords

CANCER ANTIBODY; INVOLUCRIN;

ADULT; ARTICLE; CANCER SURVIVAL; CELL KINETICS; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; KERATINOCYTE; LARYNX CARCINOMA; MALE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR DIFFERENTIATION;

EID: 0029967993     PISSN: 03077772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2273.1996.00821.x     Document Type: Article

References (89)

1. FUTRELL J.W., BENNETT S.H., HOYE R.C., ROTH J.A. & KETCHAM A.S. (1971) Predicting survival in cancer of the larynx and hypopharynx. Am. J. Surg. 122, 451-457.
2. SMITH R.R., CAULK R.M., RUSSELL W.O. & JACKSON C.L.K. (1961) End results in 600 laryngeal cancers using the American Joint Committee's proposed method of stage classification and end reporting. Surg. Gynecol. Obstet. 4353-5444.
3. MCNEILIS F.L. (1965) Laryngeal carcinoma classified by clinical staging. Arch. Otolaryngol. 82, 173-180.
4. POWELL R.W., REDD B.L. & WILKINS S.A. (1965) An evaluation of treatment of cancer of the larynx. Am. J. Surg. 110, 635-643.
5. HARRIS H.S., WATSON F.R. & SPRATT J.S. (1969) Carcinoma of the larynx: a retrospective study of 144 cases. Am. J. Surg. 110, 676.
6. UICC (1992) TNM Classification of Malignant Tumours 4th edition, 2nd revision (eds P. Hermanek & L. H. Sobin). Springer Verlag, Heidelberg.
7. GERDES J., SCHWAB U., LEMKE H. & STEIN H. (1983) Production of a monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int. J. Cancer 31, 13-20.
8. BURGER P.C., SHIBATA T. & KLEIHUES P. (1986) The use of the monoclonal antibody Ki-67 in the identification of proliferating cells: application to surgical neuropathology. Am. J. Surg. Path. 10, 611-617.
9. GERDES J., LELLE R.J., PICKARTZ H., HEIDENREICH W., SCHWARTING R., KURTSIEFER L., STAUCH G., STEIN H. (1986) Growth fractions in breast carcinomas determined in situ with monoclonal antibody Ki67. J. Clin. Path. 39, 977-980.
10. RAYMOND W.A., LEONG A.S-Y., BOLT J.W., MILIOS J., JOSE J. (1988) Growth fractions in human prostatic carcinoma determined by Ki-67 immunostaining. J. Path. 156, 161-167.
11. MELLON K., NEAL D.E., ROBINSON M.C., MARSH C., WRIGHT C. (1990). Cell cycling in bladder carcinoma determined by monoclonal antibody Ki67. Br. J. Urol. 66, 281-285.
12. SWANSON S.A., BROOKS J.J. (1990) Proliferation markers Ki-67 and p105 in soft-tissue lesions. Correlation with DNA flow cytometric characteristics. Am. J. Path. 137, 1491-1500.
13. PICH A., VALENTE G., MARGARIA E., AZZONI L., TASSO M., STRAMIGNONI A. (1991) Argyrophilic nucleolar organizer region counts and Ki67 scores in human renal cell carcinoma. Path. Res. Prac. 187, 482-486.
14. DUE W., DIECKMANN K.P., LOY V. (1988) Immunohistological determination of proliferative activity in seminomas. J. Clin. Path. 41, 304-307.
15. ISOLA J.. KALLIONIEMI D.P., KORTE J.M. et al. (1990) Steroid receptors and Ki67 reactivity in ovarian cancer and in normal ovary: correlation with DNA flow cytometry, biochemical receptor assay and patient survival. J. Path. 162, 295-301.
16. SHEPHERD N.A., RICHMAN P.I., ENGLAND J. (1988). Ki-67 derived proliferative activity in colorectal adenocarcinoma with prognostic correlations. J. Path. 155, 213-219.
17. ROLAND N.J. CASLIN A.W., BOWIE G.L., JONES A.S. (1994) Has the cellular proliferation marker Ki67 any clinical relevance in squamous cell carcinoma of the head and neck? Clin. Otolaryngol. 19, 13-18.
18. KEY G., BECKER M.H.G., DUCHROW M., SCHLUTER C., GERDES J. (1992) New Ki-67 equivalent murine monoclonal antibodies (MIB1-3) prepared against recombinant parts of the Ki-67 antigen. Ann. Cell Path. 4, 181.
19. WYLLIE A.H. (1987). Apoptosis: cell death in tissue regulation. J. Path. 153, 313-320.
20. BRODERS A.C. (1920) Squamous cell epithelioma of the lip. JAMA 74, 656-664.
21. ARTHUR K., FARR H.W. (1972) Prognostic significance of histologic grade in epidermoid carcinoma of the mouth and pharynx. Am. J. Surg. 124, 489-492.
22. BYRNE M. (1991) Prognostic value of various molecular and cellular features in oral squamous cell carcinoma: a review. J. Oral Path. Med. 20, 413-420.
23. PLATZ H., FIRES R., HUDEC M., MIN T.J.P.A., WAGNER R. (1983) The prognostic relevance of various factors at the time of the first admission of the patient. Retrospective study on carcinoma of the oral cavity. J. Maxillofac Surg. 11, 3-12.
24. ROLAND N.J., CASLIN A.W., NASH J., STELL P.M. (1992) Value of grading squamous cell carcinoma of the head and neck. Head and Neck 14, 224-229.
25. JAKOBBSSON P., ENEROTH C.M., KILLANDER D., MOBERGER G., MARTENSSON B. (1973) Histological classification and grading of malignancy in carcinoma of the larynx. Acta Radiol:- Ther.-Phys.-Biol. 12, 1-8.
26. ENEROTH C.M., MOBERGER G. (1973) Histological malignancy grading of squamous cell carcinoma of the palate. Acta Otolaryngol. 75, 293-295.
27. ANNEROTH G., HANSEN I.S., SILVERMAN J.S. (1986) Malignancy grading in oral squamous cell carcinomas. J. Oral. Path. 15, 162-168.
28. CRISSMAN J.D., LIU W.Y., GLUCKMAN J.L., CUMINGS G. (1984) Prognostic value of histopathological parameters in squamous cell carcinoma of the oropharynx. Cancer 54, 2995-3001.
29. FISHER H.R. (1975) Grading of biopsies of laryngeal carcinoma by multiple criteria. Can. J. Otolaryngol. 4, 881-884.
30. LUND C., SOGAARD H., ELBROND O., JORGENSEN K., ELBROND O., HJEIM-HANSEN M., ANDERSEN P. (1977) Histological grading of epidermoid carcinoma in the head and neck. Dan. Med. Bull. 4, 162-168.
31. WILLEN R., NATHANSON A., MOBERGER G., ANNEROTH G. (1975) Squamous cell carcinoma of the gingiva. Histological classification and grading of malignancy. Acta Otolaryngol. 79, 146-154.
32. HOLM L.E., LUNDQUIST P., SILVERSVARD C., SOBIN A. (1982) Histological grading of malignancy in squamous cell carcinoma of the oral tongue. Acta Otolaryngol. 94, 185-192.
33. YAMAMOTO E., MIYAKAWA A., KOHAMA G.I. (1984) Mode of invasion and lymph node metastases in squamous cell carcinoma of the oral cavity. Head and Neck Surg. 6, 983-987.
34. GRAEM N., HELWEG-LARSEN K., KEIDING N. (1980) Precision of histological grading of malignancy. Acta. Pathol. Microbiol. 88, 307-317.
35. WILLIAMS J.G., PENMAN S. (1975) The messenger RNA sequences in growing and resting mouse fibroblasts. Cell 6, 197-205.
36. SUN T.T., GREEN H. (1976) Differentiation of the epidermal keratinocyte in cell culture: formation of the cornified envelope. Cell 9, 511-521.
37. GREEN H. (1977) Terminal differentiation of cultured human epidermal cells. Cell 11, 405-416.
38. RICE R.H., GREEN H. (1977) The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein. Cell 11, 417-422.
39. RICE R.H., GREEN H. (1979) Presence of human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell 18, 681-694.
40. GREEN H. (1980) The keratinocyte as differentiated cell type. Harvey Lecture 74, 101-138.
41. BANKS-SCHLEGEL A., GREEN H. (1981) Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia. J. Cell Biol. 90, 732-737.
42. SAID J.W., NASH G., SASSOON A.F., SHINTAKY J.P., BANKSSCHLEGEL S. (1983) Involucrin in lung tumors. A specific marker for squamous differentiation. Lab. Invest. 49, 563-568.
43. WARHOL M,J. ANTOMOLI D.A., PINKHUS G.S., BURKE L., RICE R.H. (1982) Immunoperoxidase staining for involucrin: a potential diagnostic aid in cervicovaginal pathology. Human Pathol. 13, 1095-1099.
44. KAPLAN M.J., MILLS S.E., RICE R.H., JOHN M.E. (1984) Involucrin in laryngeal dysplasia. Arch. Otolaryngol. 110, 713-717.
45. KAMINO H., HUANG S.J., Fu Y.S. (1988) Keratin and involucrin immunohistochemistry of nasopharyngeal carcinoma. Cancer 61, 1142-1148.
46. TOTO P.D., NADAMI H., MAYWOOD M.S. (1990) Coexpression of cytokeratins, involucrin and blood group antigens in oral squamous cell carcinomas. Oral Surg., Oral Med., Oral Path. 70, 75-80.
47. AJC (1983). American Joint Committee for Cancer Staging and End Result Reporting. Manual for Staging Cancer 2nd edition. J.P. Lippincott Company, Philadelphia.
48. CHALKLEY H.W. (1943) Method for the quantitative morphologic analysis of tissues. J. Nat. Cancer Inst. 4, 47-53.
49. SAS Institute Inc. (1985) User's Guide: Statistics Version 5th edition. SAS Institute Inc. Cary, North Carolina.
50. ARMITAGE P., BERRY G. (1987) In: Statistical Methods in Medical Research 2nd edition. Heinemann Medical Books, London, pp. 169-177.
51. PETO R., PIKE M.A., ARMITAGE P., BRESLOW N.E., Cox D.R., HOWARD S.V., MANTEL N., MCPHERSON K., PETO J., SMITH P.G. (1977) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br. J. Cancer 35, 1-39.
52. COX D.R. (1972) Regression models and life-tables (with Discussion). J. Roy. Stat. Soc. B34, 187-220.
53. TUBIANA M., COURDI A. (1989) Cell proliferation kinetics in human solid tumours: relation to probability of metastatic dissemination and long-term survival. Radiother. Oncol. 15, 1-18.
54. CHAUVEL P., COURDI A., GIOANNI J., VALLICIONI J., SANTINI J., DEMARD F. (1989) The labelling index: a prognostic factor in head and neck carcinoma. Radiother. Oncol. 14, 231-237.
55. SAKUMA J. (1980) Cell kinetics of human squamous cell carcinomas in the oral cavity. Bull. Tokyo Med. Dent. Univ. 27, 43-54.
56. SILVESTRINI R., MOLINARI R., COSTA A., VOLTERRANI F., GARDANI G. (1984) Short-term variation in labelling index as a predictor of radiotherapy response in human oral cavity carcinoma. Int. J. Radit. Oncol. Biol. Phys. 10, 965-970.
57. ENSLEY J.F., MACIOROWSKI Z., HASSAN M., PIETRASZKIEWICZ H., HEILBRUN L., KISH J.A., TAPAZOGLOU E., JACOBS J.R., AL-SARRAF M. (1989) Cellular DNA content parameters in untreated and recurrent squamous cell cancers of the head and neck. Cytometry 10, 334-338.
58. 1 lip carcinomas. Clin. Otolaryngol. 12, 81-87.
59. GRAESSEL-PIETRUSKY R., HORNSTEIN O.P. (1982) Flow cytometric measurement of ploidy and proliferative activity of carcinomas of the oropharyngeal mucosa. Arch. Dermatol. Res. 273, 121-128.
60. JOHNSON T.S., WILLIAMSON K.D., CRAMER M.M., PETERS L.J. (1985) Flow cytometric analysis of head and neck carcinoma DNA index and S-fraction from paraffin-embedded sections: comparison with malignancy grading. Cytometry 6, 461-470.
61. SAKR W., HUSSAN M., ZARBO R.J., ENSLEY J., CRISSMAN J.D. (1989) DNA quantitation and histologie characteristics of squamous cell carcinoma of the upper aerodigestive tract. Arch. Path. Lab. Med. 113, 1009-1014.
62. BENNETT M.H., WILSON G.D., DISCHE S., SAUNDERS M.I., MARTINDALE C.A., ROBINSON B.M., O'HALLORAN A.E., LESLIE M.D., LAING J.H.E. (1992) Tumour proliferation assessed by combined histological and flow cytometric analysis: implication for therapy in squamous cell carcinoma of the head and neck. Br. J. Cancer 65, 870-878.
63. HEMMER J. (1990) In vitro bromodeoxyuridine labelling of squamous cell carcinomas of the oral cavity. Eur. J. Cancer 26, 113-115.
64. HIRANO T., ZITSCH R.P., GLUCKMAN J.L. (1991). The use of bromodeoxyuridine cytokinetic studies as a prognostic indicator of cancer of the head and neck. Laryngoscope 101, 130-133.
65. WILSON G.D., MCNALLY N.J., DISCHE S., SAUNDERS M.I., DES ROCHERS C., LEWIS A.A.. BENNETT M.H. (1988) Measurement of cell kinetics in human tumours in-vivo using bromodeoxyuridine incorporation and flow cytometry Br. J. Cancer 58, 423-431.
66. COOKE L.D., COOKE T.G., FORSTER G., JONES A.S., STELL P.M. (1994) Prospective evaluation of cell kinetics in head and neck squamous carcinoma: the relationship to tumour factors and survival. Br. J. Cancer 69, 717-720.
67. BALZI M., NINU B.M., BECCIOLINI A., SCUBIA E., BOANINI P., GALLINA E., GALLO O., FINI-STORCHI O., BONDI R. (1991) Labelling index in squamous cell carcinoma of the larnyx. Head and Neck 13, 344-348.
68. KEARSLEY J.H., FURLONG K.L., COOK R.A., WATERS M.J. (1990) An immunohistochemical assessment of cellular proliferation markers in head and neck squamous cell cancers. Br. J. Cancer 61, 821-827.
69. BARNARD N.J., HALL P.A., LEMIONE N.R., KADAR N.J. (1987) Proliferative index in breast carcinoma determined by Ki67 immunostaining and its relationship to pathological and clinical variables. J. Path 152, 287-295.
70. FRANKLIN W.A., BIBBO M., OSRIA M.I., DYTCH H.E., TOTH J., DESOMBRE E., WIED G.L. (1987) Quantification of oestrogen receptor and Ki67 staining in breast carcinoma by the micro TJCAS image analysis system. Analyt. Quantit. Cytol. Hist. 9, 279-281.
71. HALL P.A., RICHARDS M.A., GREGORY W.M., D'ARDENNE A.J., LISTER T.A., STANSELD A.G. (1988) The prognostic significance of Ki67 immunostaining in non-Hodgkin's lymphoma. J. Path. 154, 223-235.
72. GERDES J., STEIN H., RIVARO M.T., GOBBI M., RALFKIAER E., NIELSON K.M., PALLESEN G., BARTELS H., PALESTRO G., DELSOL G. (1987) Prognostic relevance of tumour cell growth fraction in malignant non-Hodgin's lymphoma. Lancet ii, 448-449.
73. KEY G., BECKER M.H.G., DUCHROW M., SCHLUTER C., GERDES J. (1992) New Ki-67 equivalent murine monoclonal antibodies (MIB1-3) prepared against recumbinant parts of the Ki-67 antigen. Ann. Cell. Path. 4, 181 (abstract).
74. PICH A., PONTI R., VALENTE G., CHIUSA L., GEUNA M., NOVERO D., PALESTRO G. (1994) MIB-1, Ki67 and PCNA scores and DNA flow cytometry in intermediate grade malignant lymphomas. J. Clin. Path. 47, 18-22.
75. MCCORMICK D., YU C., HOBBS C., HALL P.A. (1993) The tolerance of antibody concentration to the immunohistological quantification of cell proliferation-associated antigens. Histopathology 22, 543-547.
76. BROWN D.C., COLE D., GATTER K.C., MASON D.Y. (1988) Carcinoma of the cervix uteri: an assessment of tumour proliferation using the monoclonal antibody Ki67. Br. J. Cancer 57, 178-181.
77. SOOMRO I.N., WHIMSTER W.F. (1990) Growth fraction in lung tumours determined by Ki67 immunostaining and comparison with AgNOR scores. J. Path. 162, 217-222.
78. BOUZUBER N., WALKER K.L., GRIFTHS K., ELLIS J.O., ELSTOR C.W., ROBERTSON J.F.R., BLANEY R.W., NICHOLSON R.I. (1989) Ki67 immunostaining in primary breast cancer-pathological and clinical associations. Br. J. Cancer 59, 943-947.
79. ISOLA J., HELIN J., HELLE M.J., KALLIONIERI O. (1990) Evaluation of cell proliferation in breast carcinoma. Comparison on Ki67 immunohistochemical study. DNA flow cytometric analysis and mitotic count. Cancer 65, 1180-1184.
80. FORSCHEN R., LOHE B., HENGLES K.J., BORCHARD F. (1989) Assessment of cell proliferation in colorectal carcinomas using the monoclonal antibody Ki67: correlation with pathohistologic criteria and influence of radiation. Cancer 64, 2501-2505.
81. SUO Z., HOLM R., NEOLAND J.M. (1993) Squamous cell carcinomas. An immunohistochemical study of cytokeratins and involucrin in primary and metastatic tumours. Histopathology 23, 45-54.
82. WILLIAMS M.L., NETTESHIEM P. (1973) Lung colony assay with a squamous cell carcinoma derived from the respiratory tract of mice. J. Nat. Cancer Inst. 51, 1513-1515.
83. STEEL G.G. (1977) Growth Kinetics of Tumours - Cell Population Kinetics in Relation to the Growth and Treatment of Cancer. Oxford: Clarendon Press.
84. BYRNE M., KOPPANG H.S., LILLENG R., STENE T., BARG G., DABELSTEEN E. (1989) New malignancy grading is a better prognostic indicator than Broders grading in oral squamous cell carcinomas. J. Oral Path. Med. 18, 432-437.
85. BYRNE M., THRANE P.S., DABELSTEEN E. (1991) Loss of expression of blood group antigen H is associated with cellular invasion and spread of oral squamous cell carcinomas. Cancer 67, 613-618.
86. TUBIANA M. (1988) Repopulation in human tumours: a biological background for fractionation in radiotherapy. Acta Oncol. 27, 83-88.
87. MALAISE E.P., CHOWANDRA N., GUICHARD M., COOVDI A., VAZAUEZ T. (1978) The influence of tumour growth kinetics on the response to radiation therapy and drug therapy in man. In: Fundamentals in Cancer Chemotherapy, Antibiotics and Chemotherapy, vol 23 (F.M. Schabel ed.), Karger, Birmingham, pp. 181-190.
88. OGAWA Y., INOMETA T., NISHIOKA A., MAEDAR T., SEGUCHI H., KISHINIOTO A. et al. (1992) Changes in the Ki67 labelling rates of head and neck squamous cell carcinomas during preoperative radiation therapy. Oncology 49, 450-453.
89. VALENTE G., OECCHIAR R., GANDOLFO S., ARNAUDO M., RAGONA R., KERIM S., PALESTRO G., (1994) Can Ki67 immunostaining predict response to radiotherapy in oral squamous cell carcinoma? J. Clin. Path. 47, 109-112.