Antinociceptive effect of purine nucleotides

Brazilian Journal of Medical and Biological Research

Volumn 29, Issue 10, 1996, Pages 1379-1387

  Mello, C F ^a   Begnini, J ^a   De La Vega, D D ^a   Lopes, F P ^a   Schwartz, C C ^a   Jimenez Bernal, R E ^a   Bellot, R G ^b   Frussa Filho, R ^b  

^a DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

adenosine; anti inflammatory agents; antinociception; ATP; caffeine; inflammatory response; methylxanthines; P1 receptors; P2 receptors; purinergic transmission; theoph ylline

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; CAFFEINE; NALOXONE; PURINE NUCLEOTIDE; PURINE RECEPTOR; QUINIDINE; SURAMIN; THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; INFLAMMATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; PAIN; PURINE METABOLISM; WRITHING TEST;

ANALGESICS; ANIMALS; CAFFEINE; MALE; MICE; NALOXONE; NARCOTIC ANTAGONISTS; NOCICEPTORS; PURINE NUCLEOTIDES; QUINIDINE; RECEPTORS, PURINERGIC P1; RECEPTORS, PURINERGIC P2; ROSANILINE DYES; SURAMIN; THEOPHYLLINE;

ANIMALIA;

EID: 0029967923     PISSN: 0100879X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Yarbrough GG & McGuffin-Clineschimidt JC (1981). In vivo behavioral assessment of central nervous system purinergic receptors. European Journal of Pharmacology, 76: 137-144.
2. Sawynok J & Sweeney MI (1989). The role of purines in nociception. Neuroscience, 32: 557-569.
3. Fastbom J, Post C & Fredholm B (1990). Antinociceptive effects and spinal distribution of two adenosine receptor agonists after intrathecal administration. Pharmacology and Toxicology, 66: 69-72.
4. Sawynok J, Reid A & Nance D (1991). Spinal antinociception by adenosine analogs and morphine after intrathecal administration of the neurotoxins capsaicin, 6-hydroxydopamine and 5,7-dihydroxytryptamine. Journal of Pharmacology and Experimental Therapeutics, 258: 370-380.
5. Fredholm BB (1995). Adenosine, adenosine receptors and the actions of caffeine. Pharmacology and Toxicology, 76: 93-101.
6. 6-(R-phenylisopropyl)-adenosine (PIA) and caffeine on nociception and morphine-induced analgesia, tolerance and dependence in mice. European Journal of Pharmacology, 112: 171-179.
7. Daval J-L, Nehlig A & Nicholas F (1991). Physiological and pharmacological properties of adenosine: therapeutic implications. Life Sciences, 49: 1435-1453.
8. Stone TW (1981). Physiological roles for adenosine and adenosine 5′-triphosphate in the nervous system. Neuroscience, 6: 523-555.
9. Gomaa AA (1987). Characteristics of analgesia induced by adenosine triphosphate Pharmacology and Toxicology, 61: 199-202.
10. Doi T, Kuzuna S & Maki Y (1987). Spinal antinociceptive effects of adenosine compounds in mice. European Journal of Pharmacology. 137: 227-231.
11. Trams EG, Lauter CJ & Salem Jr N (1981). Interspecies variation of divalent cation-activated ecto-ATPases. Comparative Biochemistry and Physiology, 69B: 195-199.
12. Nagy AK, Shuster TA & Delgado-Escueta AV (1986). Ecto-ATPase of mammalian synaptosomes: identification and enzymic characterization. Journal of Neurochemistry, 47: 976-986.
13. Sweeney MI, White TD & Sawynok J (1987). Involvement of adenosine in the spinal antinociceptive effects of morphine and noradrenaline. Journal of Pharmacology and Experimental Therapeutics, 243: 657-665.
14. 2+-ATPase activities in human hepatoma cells. Archives of Biochemistry and Biophysics, 263: 264-271.
15. Rocha JBT, Mello CF, Sarkis JJF & Dias RD (1990). Undernutrition during preweaning period changes calcium ATPase and ADPase activities of synaptosomal fractions of weanling rats. British Journal of Nutrition, 63: 273-284.
16. Torres M, Pintor J & Miras-Portugal MT (1990). Presence of ectonucleotidases in cultured chromaffin cells: hydrolysis of extracellular adenine nucleotides. Archives of Biochemistry and Biophysics, 279: 37-44.
17. Meghji P, Pearson JD & Slakey LL (1992). Regulation of extracellular adenosine production. American Journal of Physiology, 263: H40-H47.
18. Ziganshin AU, Hoyle CHV & Burnstock G (1994). Ecto-enzymes and metabolism of extracellular ATP. Drug Development Research, 32: 134-146.
19. Jessell TM & Jahr CE (1986). Synaptic interactions between dorsal root ganglion and dorsal horn neurons in cell culture: amino acids, nucleotides, and peptides as possible fast and slow excitatory transmitters. In: Iversen LL & Goodman EC (Editors), Fast and Slow Chemical Signalling in the Nervous System. Oxford University Press, Oxford, 164-184.
20. Ho BT, Huo YY, Lu JG, Newman RA & Levin VA (1992). Analgesic activity of anti-cancer agent suramin. Anti-Cancer Drugs, 3: 91-94.
21. Hayashi G & Takemori AE (1971). The type of analgesic receptor interaction involved in certain analgesic assays. European Journal of Pharmacology, 16: 63-69.
22. Hunskaar S & Hole K (1987). The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain, 30: 103-114.
23. Shibata M, Ohkubo T, Takahashi H & Inoki R (1989). Modified formalin test: characteristic biphasic response. Pain, 38: 347-352.
24. Burnstock G (1972). Purinergic nerves. Pharmacological Reviews, 24: 509-581.
25. Gebhart GF & Ness TJ (1991). Central mechanisms of visceral pain. Canadian Journal of Physiology and Pharmacology, 69: 627-635.
26. O'Connor SE, Dainty IA & Left P (1991). Further classification of ATP receptors based on agonist studies. Trends in Pharmacological Sciences, 12: 137-141.
27. Lorenzetti BB & Ferreira SH (1986). Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia. European Journal of Pharmacology, 114: 375-381.
28. Ho IK, Loh HH & Way EL (1973). Cyclic adenosine monophosphate antagonism of morphine analgesia. Journal of Pharmacology and Experimental Therapeutics, 185: 336-346.
29. Jurna I (1984). Cyclic nucleotides and aminophylline produce different effects on nociceptive motor and sensory responses in the rat spinal cord. Naunyn-Schmiedeberg's Archives of Pharmacology, 327: 23-30.
30. Sweeney MI, White TD & Sawynok J (1991). Intracerebroventricular morphine releases adenosine and adenosine 3′,5′-cyclic monophosphate from the spinal cord via a serotonergic mechanism. Journal of Pharmacology and Experimental Therapeutics, 259: 1013-1018.
31. Nielson C & Vestal RE (1989). Effects of adenosine on polymorphonuclear leucocyte function, cyclic 3′:5′-adenosine monophosphate, and intracellular calcium. British Journal of Pharmacology, 97: 882-888.
32. Cronstein BN (1994). Adenosine, an endogenous anti-inflammatory agent. Journal of Applied Physiology, 76: 5-13.
33. 3H]NECA in rat membranes. Molecular Pharmacology, 29: 331-346.