Structure/function analysis of human factor XII using recombinant deletion mutants: Evidence for an additional region involved in the binding to negatively charged surfaces

European Journal of Biochemistry

Volumn 238, Issue 1, 1996, Pages 240-249

  Citarella, Franca ^a,b,c   Ravon, Dorothea M ^b   Pascucci, Barbara ^a   Felici, Angelina ^a   Fantoni, Antonio ^a   Hack, C Erik ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c CENTRAL LABORATORY   (Netherlands)

Author keywords

Binding site; Deletion mutant; Human factor XII; Negatively charged surface

Indexed keywords

BLOOD CLOTTING FACTOR 12; PREKALLIKREIN; RECOMBINANT PROTEIN;

ARTICLE; BINDING SITE; BLOOD CLOTTING; CELL STRAIN HEPG2; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOAFFINITY CHROMATOGRAPHY; KRINGLE DOMAIN; NORMAL HUMAN; PARTIAL THROMBOPLASTIN TIME; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PURIFICATION; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; BINDING SITES; BLOOD COAGULATION; DEXTRAN SULFATE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FACTOR XII; GLASS; HUMANS; IODINE RADIOISOTOPES; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; PREKALLIKREIN; RECOMBINANT PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029967088     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0240q.x     Document Type: Article

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