Decreased serum antioxidant activity of hemodialysis patients demonstrated by methylguanidine synthesis and microsomal lipid peroxidation

Nephron

Volumn 74, Issue 3, 1996, Pages 555-560

  Nagase, Sohji ^a   Aoyagi, Kazumasa ^a   Hirayama, Aki ^a   Gotoh, Michihiro ^a   Ueda, Atsushi ^a   Tomida, Chie ^a   Kikuchi, Hiroshi ^b   Takemura, Katsumi ^c   Toyama, Akio ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Tsukuba Gakuen Hospital   (Japan)

^c Kamitsuga General Hospital   (Japan)

Author keywords

Hemodialysis; Methylguanidine; Microsomal lipids peroxidation; Serum antioxidant activity; Thiobarbituric acid reactive substance

Indexed keywords

CREATININE; LIPID; METHYLGUANIDINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEMODIALYSIS; HUMAN; LIPID PEROXIDATION; MALE; PRIORITY JOURNAL; UREMIA;

EID: 0029966889     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000189451     Document Type: Article

References (29)

1. Freeman BA, Crapo JD: Free radical and tissue injury, Lab Invest 1982:47:412-426.
2. Weitzman SA, Stossel TP: Effect of oxygen radical scavengers and antioxidants on phagocyte-induced mutagenesis, J Immun 1982:128: 2770-2772.
3. Paller MS, Hoidal JR, Ferris TF: Oxygen free radicals in ischemic acute renal failure in the rat, J Clin Invest 1984:74:1156-1164.
4. Rehan A, Johnson KJ, Wiggins RC, Kunkcl RG, Ward PA: Evidence for the role of oxygen radicals in acute nephrotic nephritis, Lab Invest 1984:51:396-403.
5. Cohen MV: Free radicals in ischemic and re-perfusion myocardial injury: Is this time for clinical trials? Ann Intern Med 1989:111:918-931.
6. Zachee P, Ferrat A, Daclemans R, Coolen L, Goosens W, Lins RL, Couttenye M, De Broe ME, Boogaerts ME: Oxidative injury to erythrocytes, cell rigidity and splenic hemolysis in hemodialyzed patients before and during erythropoietin treatment, Nephron 1993:65: 288-293.
7. Maggi E, Bellazzi R, Gazo A, Scccia M, Bcllo-mo G: Autoantibodies against oxidatively-modified LDL in uremic patients undergoing dialysis, Kidney Int 1994:46:869-876.
8. Southorn PA, Powis G: Radicals in medicine, II, Improvement in human disease, Mavo Clin Proc 1988:63:390-408.
9. Pritsos CA, Sartorelli AC: Generation of reactive oxygen radicals through bioactivalion of mitomycin antibiotics, Cancer Res 1986:46: 3528-3532.
10. Giovannetti S, Biagni M, Balestri PL, Navalcsi R, Giagnoni P, Matteis A, Ferro-Milone P, Per-fetti C: Uremia-like syndrome in dogs chronically intoxicated with methylguanidine and creatinine, Clin Sci 1969:36:445-452.
11. Giovannetti S, Balestri PL, Barsotti G: Methyl-guanidine in uremia, Arch Intern Med 1973: 131:709-713.
12. Barsotti G, Bevilacqua G, Morelli E, Cappelli P, Balestri PL, Giovannetti S: Toxicity arising from guanidine compounds: Role of methyl-guanidine as a uremic toxin, Kidney Int 1975: 7:S299-S30I.
13. D’Hoogc R, Pei Y, Marescau B, DcDeyn PP: Ontogenetic differences in convulsive action and cerebral uptake of uremic guanidino compounds in juvenile mice, Neurochem Int 1994: 24:214-220.
14. DcDeyn PP, Marescau B, D’Hooge R, Posse-miers I, Nagler J, Mahler CH: Guanidino compound levels in brain regions of non-dialyzed uremic patients, Neurochem Int 1995:27:227-237.
15. Nagase S, Aoyagi K, Narita M, Tojo S: Active oxygen in methylguanidine synthesis, Nephron 1986:44:299-303.
16. Aoyagi K, Nagase S, Narita M, Tojo S: Role of active oxygen on methylguanidine synthesis in-isolated hcpatocytes, Kidney Int 1987;22: S229-S232.
17. Nagase S, Aoyagi K, Sakamoto M, Takentura K, Ishikawa T, Narita M: Biosynthesis of meth-ylguanidinc in the hepatic microsomal fraction, Nephron 1992;62:182-186.
18. Giardini O, Taccone-Gallucci M, Lubrano R, Riccardi-Tcnorc G, Bandino D, Silvi I: Evidence of red blood cell membrane lipid peroxidation in haemodialysis patients, Nephron 1984:36:235-237.
19. Kuroda M, Asaka S, Tofuku Y, Takeda R: Serum antioxidant activity in uremic patients, Nephron 1985;41:293-298.
20. Pederson TO, Aust SD: NADPH-dependent lipid peroxidation catalyzed by purified NADPH-cytochrome C reductase from rat liver microsomes, Biochem Biophys Res Com-mun 1972:48:789-795.
21. Beers RF, Silver IW: A spcctrophotometric method for measuring the breakdown of hydrogen peroxide by catalase, J Biol Chem 1952; 195:133-140.
22. Sanz DC, Santa-Cruz MC: Simultaneous measurement of retinol and a-tocopherol in human serum by high-performance liquid chromatography with ultraviolet detection, J Chromatogr 1986:380:140-144.
23. Gutteridge JM, Maidt L, Poyer L: Superoxide dismutase and Fenton chemistry, Biochem J 1990:269:169-174.
24. Nagase S, Aoyagi K, Narita M, Tojo S: Biosynthesis of methylguanidine in isolated rat hepa-tocytes and in vivo, Nephron 1985:40:470-475.
25. Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction, Anal Biochem 1979:95:351-358.
26. Nagase S, Aoyagi K, Sakamoto M, Narita M, Tojo S: Evidence for the role of active oxygen in guanidine synthesis in haemodialysis patients and in vitro, Nephrol Dial Transplant 1988:3:790-794.
27. Lucchi L, Cappelli G, Angela Acerbi M, Spat-tini A, Lusvarghi E: Oxidative metabolism of polymorphonuclear leukocytes and serum opsonic activity in chronic renal failure, Nephron 1989:51:44-50.
28. Lucchi L, Banni S, Boni B, Cappelli G, Medici G, Paolo Melis M, Tomasi A, Vannini V, Lusvarghi E: Conjugated diene fatty acids in patients with chronic renal failure: Evidence of increased lipid peroxidation, Nephron 1993: 65:401-409.
29. Sugioka K, Nakano M: A possible mechanism of the generation of singlet molecular oxygen in NADPH-dependent microsomal lipid peroxidation, Biochim Biophys Acta 1976:423:203-216.