Mizolastine. Antihistamine, histamine H1-receptor antagonist

Drugs of the Future

Volumn 21, Issue 8, 1996, Pages 799-804

  Mealy, N ^a   Ngo, J ^a   Castaner J ^a  

^a PROUS SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ASTEMIZOLE; CETIRIZINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; LORATADINE; MIZOLASTINE; TERFENADINE;

ANAPHYLAXIS; BRAIN REGION; BRONCHOSPASM; CEREBELLUM; CONJUNCTIVITIS; DROWSINESS; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SYNTHESIS; ELECTROENCEPHALOGRAM; FATIGUE; GUINEA PIG; HEADACHE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; SEDATION; SHORT SURVEY; URTICARIA;

EID: 0029966799     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.1996.021.08.368281     Document Type: Short Survey

References (44)

1. Manoury, P., Binet, J., Defosse, G. (Synthélabo Labs.). Benzimidazole derivs., their preparation and their application in therapeutic. EP 217700, FR 2587029, JP 87061979, US 4820710.
2. Prous, J.R. Treatment of upper respiratory tract disorders. In: The Year's Drug News - Therapeutic Targets, 1995 Edition, Prous Science Publishers, Barcelona, 1995,141-7.
3. 1 -receptor antagonist properties. Eur J Pharmacol 1990, 183(2): Abst P.mo.010.
4. 1 receptors in the rodent. Arzneim-Forsch-Drug Res 1995, 45:551-8.
5. Levrier, J., Duval, D., Prouteau, M. et al. Anti-anaphylactic activity of the novel selective histamine HI receptor antagonist mizolastine in the rodent. Arzneim-Forsch-Drug Res 1995, 45: 559-68.
6. 1 receptor antagonist: Lack of sedative potential on the EEG in the rodent. Neuropsychobiology 1995,32:214-21.
7. 1 antihistamines. Clin Pharmacokin 1995, 28:419-32.
8. Dubruc, C., Deschamps, C., Fraisse, J., Thenot, J.P., Bianchetti, G. Pharmacokinetic profile of mizolastine, a new antihistamine drug. Allergy 1996, 51(Suppl. 31): Abst P 514.
9. 1 antihistamine. Ann Allergy 1992, 69:135-9.
10. Ascalone, V., Guinebault, P., Rouchouse, A. Determination of mizolastine, a new antihistaminic drug, in human plasma by liquidliquid extraction, solid-phase extraction and column-switching techniques in combination with high-performance liquid chromatography. J Chromatogr Biomed Appl 1993, 619: 275-84.
11. Leynadier, F., Bousquet, J., Murrieta, M. et al. Efficacy and safety of mizolastine in seasonal allergic rhinitis. Ann Allergy Asthma Immunol 1996, 76:163-8.
12. Pinquier, J.-L, Caplain, H., Cabanis, M.-J., Dubruc, C., Stalla-Bourdillon, A., Rosenzweig, P. Inhibition of histamine-induced skin wheal and flare after 5 days of mizolastine. J Clin Pharmacol 1996, 36: 72-8.
13. Rosenzweig, P., Caplain, H., Chaufour, S., Ulliac, N., Cabanis, M.J., Thebault, J.J. Comparative wheal and flare study of mizolastine vs terfenadine, cetirizine, loratadine and placebo in healthy volunteers. Brit J Clin Pharmacol 1995, 40:459-65.
14. O'Hanlon, J.F, Ramaekers, J.G. Antihistamine effects on actual driving performance in a standard test: A summary of Dutch experience, 1989-94. Allergy 1995, 50: 234-42.
15. Kerr, J.S., Dunmore, C., Hindmarch, I. The psychomotor and cognitive effects of a new antihistamine, mizolastine, compared to terfenadine, triprolidine and placebo in healthy volunteers. Eur J Clin Pharmacol 1994, 47: 331-5.
16. Patat, A., Stubbs, D., Dunmore, C., Ulliac, N.,Sexton, B., Zieleniuk, I., Irving, A., Jones, W. Lack of interaction between two antihistamines, mizolastine and cetirizine, and ethanol in psychomotor and driving performance in healthy subjects. Eur J Clin Pharmacol 1995,48: 143-50.
17. Patat, A., Perault, M.C., Vandel, B., Ulliac, N., Zieleniuk, I., Rosenzweig, P. Lack of interaction between a new antihistamine, mizolastine, and lorazepam on psychomotor performance and memory in healthy volunteers. Brit J Clin Pharmacol 1995,39:31-8.
18. Vuurman, E.F.P.M., Uiterwijk, M.M.C., Rosenzweig, P., O'Hanlon, J. F. Effects of mizolastine and clemastine on actual driving and psychomotor performance in healthy volunteers. Eur J Clin Pharmacol 1994, 47: 253-9.
19. Patat, A., Gram, L.F., Dubruc, C., Brohier, S., Cabanis, M.J., Rosenzweig, P. Effects of mizolastine, a new antihistamine, on psychomotor performance and memory in elderly subjects, Int Clin Psychopharmacol 1994, 9: 101-8.
20. Danjou, P., Molinier, P., Berlin, I., Patat, A., Rosenzweig, P., Morselli, P.L. Assessment of the anticholinergic effect of the new antihistamine mizolastine in healthy subjects. Brit J Clin Pharmacol 1992,34:328-31.
21. Bousquet, J., Chanal, I., Murrieta, M., Stalla-Bourdillon, A. Lack of subsensitivity to mizolastine over 8-week treatment. Allergy 1996,51:251-6.
22. Brostoff, J., Fitzharris, P., Dunmore, C., Theron, M., Blondin, P. Efficacy of mizolastine, a new antihistamine, compared with placebo in the treatment of chronic idiopathic urticaria. Allergy 1996, 51 (5): 320-5.
23. TM Data Base 1996.
24. Tasman, A.J., Scadding, G.K., Murrieta, M. An open-labeled, multi centered study of mizolastine (M): 10 mg and 15 mg/d, to assess the long-term safety and efficacy in patients suffering from perennial allergic rhino-conjunctivitis (PAR). Allergy 1996,51 (Suppl. 31 ): Abst P 518.
25. Kerr, J.S., Hindmarch, I. The comparative psychomotor and cognitive effects of a new antihistamine, mizolastine. J Psychopharmacol 1993, Abstract Book: Abst 72.
26. Pinquier, J.L., Cabanis, M.J., Ulliac, N., Dubruc, C., Rosenzweig, P. Anti-histamine activity of mizolastine. A review of the clinical pharmacology studies. Allergy 1996, 51 (Suppl. 31): Abst P 515.
27. 1 antagonist is devoid of CNS effects. A review of human pharmacology data. Allergy 1996, 51(Suppl. 31): Abst P 517.
28. 1 antagonist drug. Eur J Pharmacol 1990,183(2): Abst P.mo.388.
29. 1 antagonist drug compared to terfenadine and triprolidine in healthy subjects. Eur J Pharmacol 1990,183(2): Abst P.mo.389.
30. 1 -antagonist SL 85.0324 vs placebo and dimetinden in volunteers. Eur J Pharmacol 1990,183(2): Abst P.mo.462.
31. 1 -antihistamine SL85.0324 vs placebo and dimetinden in volunteers. Eur J Pharmacol 1990,183(2): Abst P.mo.464.
32. Stubbs, D., Blondin, P., Patat, A., Bergougnan, L., Irving, A., Clough, W. Lack of interaction between a new antihistamine, mizolastine, and ethanol on psychomotor and driving performance in healthy volunteers. Brit J Clin Pharmacol 1994, 39: 57OP.
33. Pinquier, J.-L, Michel, L, Cabanis, M.J., Dubruc, C., Ulliac, N., Rosenzweig, P., Dubertret, L. Effect of mizolastine on experimental inflammation in human skin. Clin Pharmacol Ther 1995,57(2): Abst PII-23.
34. Stern, M.A., Dunmore, C.J., Théron, M. A double-blind comparative study of mizolastine (SL85.0324) 10 mg and placebo in the treatment of seasonal allergic rhinoconjunctivitis in adult patients. Allergy 1992, 47(12): 177.
35. Patat, A., Perrault, M.C., Vandel, B., Ulliac, N., Zieleniuk, I. Study on the pharmacodynamic interaction between mizolastine and lorazepam on psychomotor performance and memory in healthy volunteers. Brit J Clin Pharmacol 1994, 37: 118P.
36. Pinquier, J.-L., Cabanis, M.J., Thébault, J.J., Dubruc, C., Rosenzweig, P. Effect of mizolastine on histamine-induced wheal and flare model in healthy volunteers. Clin Pharmacol Ther 1994,55(2): Abst PIII-2.
37. Lamprecht, J., Mösges, R., Spaeth, J. Treatment of seasonal allergic rhinitis with the new low dose histamine antagonist mizolastine. 14th Int Cong Allergol Clin Immunol (Oct 13-18, Kyoto) 1991, Abst 1051.
38. 1 antihistamine. Clin Pharmacol Ther 1995,57(2): Abst PII-25.
39. Dubruc, C., Mesnil, F., Mentré, F., Thénot, J.P., Mallet, A. Population pharmacokinetic analysis of mizolastine using a non parametric method (NPML). Clin Pharmacol Ther 1996,59(2): Abst PHI-66.
40. Berry, C.N., M'barga-Owono, D. Effects of the new antihistamine SL 85.0324 on histamine-induced eicosanoid release from the isolated perfused guinea-pig lung. Brit J Pharmacol 1991, 104(Suppl.):Abst 91P.
41. Levrier, J., Duval, D., Lloyd, K.G., Scatton, B. Anti-PAF activity of the non sedative H1 receptor antagonist SL 85.0324 in the guinea pig. J Lipid Mediator 1990, 2(3-4): Abst 64.
42. 1 -receptor antagonist. Eur J Pharmacol 1990,183(5): Abst P.th.071.
43. 1 receptor antagonist, in the guinea pig grain. Eur J Pharmacol 1990,183(5): Abst P.th.070.
44. 1 receptor antagonist SL 85.0324 in the rat and guinea pig. Eur J Pharmacol 1990,183(2): Abst P.mo.005.