High copy number I-Ab transgenes induce production of IgE through an interleukin 4-dependent mechanism

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 7, 1996, Pages 2947-2952

  Singer, Steven M ^a,b   Umetsu, Dale T ^a   Mcdevitt, Hugh O ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

B lymphocytes; immunodeficiency; major histocompatibility complex

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE DIFFERENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ETIOLOGY; HYPOGAMMAGLOBULINEMIA; IMMUNE DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; B-LYMPHOCYTES; BLOTTING, SOUTHERN; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN-4; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED NOD; MICE, INBRED STRAINS; MICE, TRANSGENIC; SPLEEN;

EID: 0029966357     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.7.2947     Document Type: Article

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