Amitraz depresses cardiovascular responses to bilateral carotid occlusion

Journal of Veterinary Pharmacology and Therapeutics

Volumn 19, Issue 1, 1996, Pages 22-26

  Reynoldson, J A ^a   Cullen, L K ^a  

^a MURDOCH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; AMITRAZ; ANTIPARASITIC AGENT; PRAZOSIN; YOHIMBINE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR REFLEX; CARDIOVASCULAR RESPONSE; CAROTID ARTERY OBSTRUCTION; CISTERNA MAGNA; CONTROLLED STUDY; DOG; DRUG ANTAGONISM; FEMALE; HEART RATE; INTRACISTERNAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL;

ANIMALIA; CANIS FAMILIARIS;

EID: 0029966346     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2885.1996.tb00003.x     Document Type: Article

References (26)

1. Antonaccio, M.J., Robson, R.D. & Kerwin L. (1973) Evidence for increased vagal tone and enhancement of baroreceptor reflex activity after xylazine (2-(2,6-dimethylphenylamino)-4-H5,6-dihydro-1,3-thiazine) in anaesthetised dogs. European Journal of Pharmacology, 23, 311-315.
2. Anon. (1977) Taktic Product Information Bulletin, revised edn. The Boots Co. (Aust.) Pty. Ltd., Nottingham, quoted by Gunaratnam, P., Wilkinson,
3. G.T. & Seawright, A.A. (1983) A study of amitraz toxicity in cats. Australian Veterinary Journal, 60, 278-279.
4. Cullen, L.K. & Reynoldson, J.A. (1987) Cardiovascular and respiratory effects of the acaricide amitraz. Journal of Veterinary Pharmacology and Therapeutics, 10, 134-143.
5. Cullen, L.K. & Reynoldson, J.A. (1988) Cardiovascular responses to amitraz in the presence of autonomic antagonists and agonists. Archives Internationales de Pharmacodynamie et de Therapie, 296, 45-56.
6. Cullen, L.K. & Reynoldson, J.A. (1990) Central and peripheral α-adrenoceptor actions of amitraz in the dog. Journal of Veterinary Pharmacology and Therapeutics, 13, 86-92.
7. Donald D.E. & Edis, A.J. (1971) Comparison of aortic and carotid baroreflexes in the dog. Journal of Physiology, 215, 521-538.
8. Dunnett, C.W. (1955) A multiple comparison procedure for comparing several treatments with a control. Journal of the American Statistical Association, 50, 1096-1121.
9. Farmer, H. & Seawright, A.A. (1980) The use of amitraz (N1-(2,4,-di-methylphenyl)-N-[(2,4-dimethylphenyl)imino)-methyl]-N-methylmet hanimidamide) in demodicosis in dogs. Australia Veterinary Journal, 50, 537-541.
10. Folz, S.D., Geng, S., Nowakowski, L.H. & Conklin, R.D. (1978) Evaluation of a new treatment for canine scabies and demodicosis. Journal of Veterinary Pharmacology and Therapeutics, 1, 199-204.
11. 2-adrenoceptors. Toxicology and Applied Pharmacology, 73, 411-415.
12. 2-adrenergic receptors. Drug Development Research, 4, 655-660.
13. Hsu, W.H. & McNeel, S.V. (1985) Amitraz-induced prolongation of gastrointestinal transit and brachycardia in dogs and their antagonism by yohimbine: A preliminary study. Drug and Chemical Toxicology, 8, 239-254.
14. 2-adrenoceptors in the modulation of the baroreflex vagal brachycardia. European Journal of Pharmacology, 71, 455-461.
15. 2-adrenoceptors in the modulation of the sympathetic component of the baroreflex. Neuropharmacology, 22, 1243-1248.
16. Karim, F., Hainsworth, R. & Pandey, R.P. (1978) Reflex responses of abdominal vascular capacitance from aortic baroreceptors in dogs. American Journal of Physiology, 235, H488-H493.
17. Kirchheim, H.R. (1976) Systemic arterial baroreceptors reflexes. Physiological Reviews, 56, 100-176.
18. Kwochka, K.W., Kunkle, G.A. & Foil, C.O. (1985) The efficacy of amitraz for generalized demodicosis in dogs: a study of two concentrations and frequencies of application. Compendium of Continuing Education for Practicing Veterinarians, 7, 8-18.
19. Muller, G.H. (1983) Amitraz treatment of demodicosis. Journal of the American Animal Hospital Association, 19, 435-441.
20. Robson, R.D. & Antonaccio, M.J. (1975) Modification of baroreceptor function by clonidine: evidence for an opposing action on baroreceptors of different location. In Recent Advances Hypertension, Vol.2. Eds Milliez, P. & Safar, M. pp. 34-47. Boehringer Ingleheim, Reims.
21. Scheffe, H. (1959) The Analysis of Variance. Wiley, New York.
22. Schmitt, H. Fournadjieve, G. & Schmitt, H. (1970) Central and peripheral effects of 2-(2,6-dimethylphenylamino)-4-H5,6-dihydro-1,3-thiazin (Bayer 1470) on the sympathetic system. European Journal of Pharmacology, 10, 230-238.
23. Seawright, A.A. (1982) The formamidines. In Chemical and Plant Poisons. Animal Health in Australia, Vol. 2. pp. 233-234. Australian Government Publishing Service, Canberra.
24. Snedecor, G.W. and Cochran, W.G. (1978) Statistical Methods. The Iowa State University Press, Ames, Iowa.
25. Spyer, K.M. (1981) Neural organisation and control of the baroreceptors reflex. Review of Physiology, Biochemistry and Pharmacology, 88, 23-124.
26. 2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents. Brain Research Reviews, 7, 69-101.