Synthesis and cytotoxic activities of the amine-exchange products of 2-dimethylaminomethyl-5-(e)-substituted arylidene cyclopentanones with anilines: 2-Arylaminomethyl-5-(5)-arylidene cyclopentanones

Drug Design and Discovery

Volumn 14, Issue 1, 1996, Pages 43-52

  Chen, Haitao ^a,b   Ji, Zhizhong ^a   Wong, Lan K ^b   Siuda, Jerome F ^b   Narayanan, Ven L ^c  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Arylidenecyclopentanones; Cytotoxic; Mannich; Synthesis

Indexed keywords

ANILINE DERIVATIVE; CYCLOPENTANONE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA;

ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; CYCLOPENTANES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; TUMOR CELLS, CULTURED;

EID: 0029965956     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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16. Carbon analyses found for 1b and 3m were within 0.6% of the theoretical values.