Influence of native and modified lipoproteins on migration of mouse peritoneal macrophages and the effect of the antioxidants vitamin E and Probucol

European Journal of Cell Biology

Volumn 71, Issue 2, 1996, Pages 199-205

  Trach, Cornelia C ^a,b   Wülfroth, Petra M ^a   Severs, Nicholas J ^c   Robenek, Horst ^b  

^a MERZ PHARMACEUTICALS GMBH   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Antioxidants; Boyden chamber; Chemotaxis; Foam cells; Lipid peroxidation; Macrophages; Migration; Probucol; Vitamin E

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ALPHA TOCOPHEROL; ANTIOXIDANT; CHEMOATTRACTANT; CHOLESTEROL; CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROBUCOL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL MIGRATION; CHEMOKINESIS; CONTROLLED STUDY; FOAM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ANIMALIA;

EID: 0029965560     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Arai, H., T. Kita, M. Yokode, S. Narumiya, C. Kawai: Multiple receptors for modified low density lipoproteins in mouse peritoneal macrophages: Different uptake mechanisms for acetylated and oxidized low density lipoproteins. Biochem. Biophys. Res. Commun. 159, 1375-1382 (1989).
2. Araki, N., S. Horiuchi, A. T. M. A. Rahim, K. Takata, Y. Morino: Microquantification of cholesterol and cholesteryl esters in rat peritoneal macrophages by reverse-phase high-performance liquid chromatography. Anal. Biochem. 185, 339-345 (1990).
3. Badimon, J. J., V. Fuster, J. H. Chesebro, L. Badimon: Coronary atherosclerosis a multifactorial disease. Circulation 87, II3-II16 (1993).
4. Basu, S. K., J. L. Goldstein, R. G. W. Anderson, M. S. Brown: Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. Proc. Natl. Acad. Sci. USA 73, 3187-3185 (1976).
5. Boyden, S. V.: The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leukocytes in vitro. J. Exp. Med. 115, 453-466 (1962).
6. Carew, T. E., D. C. Schwenke, D. Steinberg: Antiatherogenic effect of probucol unrelated to its hypocholestomic effect: Evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit. Proc. Natl. Acad. Sci. USA 84, 7725-7729 (1987).
7. Daoud, A. S., K. E. Fritz, J. Jarmolych, A. S. Frank: Role of macrophages in regression of atherosclerosis. Ann. N. Y. Acad. Sci. 454, 101-114 (1985).
8. Ferns, G. A. A., M. Konneh, E. E. Änggard: Vitamin E: The evidence for an anti-atherogenic role. Artery 20, 61-94 (1993).
9. Gerrity, R. G.: The role of the monocyte in atherogenesis. II. Migration of foam cells from atherosclerotic lesions. Am. J. Pathol. 103, 191-200 (1981).
10. Gerrity, R. G.: The role of the monocyte in atherogenesis. I. Transition of bloodborne monocytes into foam cells in fatty lesions. Am. J. Pathol. 103, 181-190 (1981).
11. Goldstein, J. L., Y. K. Ho, S. K. Basu, M. S. Brown: Binding site on macrophages that mediate uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acad. Sci. USA 76, 333-337 (1979).
12. Habeeb, A. F. S. A.: Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. Anal. Biochem. 14, 328-336 (1966).
13. Haberland, M. E., U. P. Steinbrecher: Modified low density lipoproteins: Diversity and biological relevance in atherogenesis. Monogr. Hum. Genet. 14, 35-61 (1992).
14. Hara, S., Y. Nagano, M. Sasada, T. Kita: Probucol treatment enhances the chemotaxis of mouse peritoneal macrophages. Arterioscler. Thromb. 12, 593-600 (1992).
15. Havel, R. J., H. A. Eder, J. H. Bragdon: The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34, 1345-1353 (1955).
16. Hopstock, C., H. Robenek, P. Wülfroth: Interactions between human macrophages and low density lipoproteins: Influence of antioxidants. Eur. J. Cell Biol. 60, Suppl. 37, p. 57 (1993).
17. Howard, T. H., C. O. Oresajo: The kinetics of chemotactic peptide-induced change in F-actin content, F-actin distribution, and the shape of neutrophils. J. Cell Biol. 101, 1078-1085 (1985).
18. Jackson, R. L., G. Ku, C. E. Thomas: Antioxidants: A biological defense mechanism for the prevention of atherosclerosis. Med. Res. Rev. 13, 161-182 (1993).
19. Jessup, W., R. T. Roger: Autoinhibition of murine macrophage-mediated oxidation of low-density lipoprotein by nitric oxide synthesis. Atherosclerosis 101, 145-155 (1993).
20. Johnson, W. J., F. H. Mahlberg, G. H. Rothblat, M. C. Phillips: Cholesterol transport between cells and high density lipoprotein. Biochim. Biophys. Acta. 1085, 273-298 (1991).
21. Kelley, J. L.: Macrophage scavenger receptor(s) for modified low density lipoproteins. Prog. Lipid Res. 30, 231-235 (1991).
22. Koren, E., K. Mirna, W. J. McConathy, R. D. Fugate: Possible role of macrophages in regression of atherosclerosis. Prog. Lipid. Res. 30, 237-243 (1991).
23. Kreuzer, J., J. Bader, L. Jahn, M. Hautmann, W. Kübler, E. Von Hodenberg: Chemotaxis of the monocyte cell line U937: Dependence on cholesterol and early mevalonate pathway products. Atherosclerosis 90, 203-209 (1991).
24. Liebler, D. C.: The role of metabolism in the antioxidant function of vitamin E. Crit. Rev. Toxicol. 23, 147-169 (1993).
25. Lowry, O. H., N. J. Rosenbrough, A. L. Farr, R. J. Randall: Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275 (1951).
26. McMurray, H. F., S. Parthasarathy, D. Steinberg: Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes. J. Clin. Invest. 92, 1004-1008 (1993).
27. Parthasarathy, S.: Novel atherogenic, oxidative modification of low density lipoprotein. Diabetes Metab. Rev. 7, 163-171 (1991).
28. Parthasarathy, S., S. M. Rankin: Role of oxidized low density lipoprotein in atherogenesis. Prog. Lipid Res. 31, 127-143 (1992).
29. Pataki, M., G. Lusztig, H. Robenck: Endocytosis of oxidized LDL and reversibility of migration inhibition in macrophage-derived foam cells in vitro. A mechanism for atherosclerosis regression? Arterioscler. Thromb. 12, 936-944 (1992).
30. Quinn, M. T., S. Parthasarathy, D. Steinberg: Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effect of modified forms of low density lipoprotein. Proc. Natl. Acad. Sci. USA 82, 5949-5953 (1985).
31. Ross, R.: The pathogenesis of atherosclerosis. A perspective for the 1990s. Nature 362, 801-809 (1993).
32. Schwartz, C. J., A. J. Valente, E. A. Sprague: A modern view of atherogenesis. Am. J. Cardiol. 71, 9B-14B (1993).
33. Sirtori, C. P., C. Manzoni, M. R. Lovati: Mechanisms of lipid-lowering agents. Cardiology 78, 226-235 (1991).
34. Sparrow, C. P., S. Parthasathary, D. Steinberg: A macrophage receptor that recognizes oxidized low density lipoproteins but not acetylated low density lipoprotein. J. Biol. Chem. 264, 2599-2604 (1989).
35. Steinberg, D.: Antioxidants and atherosclerosis. Circulation 84, 1420-1425 (1991).
36. Steinberg, D.: Modified forms of low-density lipoprotein and atherosclerosis. J. Int. Med. 233, 227-232 (1993).
37. Vercaemst, R., A. Union, M. Rosseneu: Separation and quantitation of free cholesterol and cholesteryl esters in a macrophage cell line by high-performance liquid chromatography. J. Chromatogr. 494, 43-52 (1989).
38. Witztum, J. L., D. Steinberg: Role of oxidized low density lipoprotein in atherogenesis. J. Clin. Invest. 88, 1785-1792 (1991).
39. Yagi, K.: A simple fluorometric assay for lipoperoxide in blood plasma. Biochem. Med. 15, 212-216 (1976).
40. Yamada, K. M.: Functions of integrins in cell adhesion and migration. AIDS Res. Hum. Retrovirus 8, 786-793 (1992).