Synthesis of 4-substituted-1,2,3,4-tetrahydro-ß-carbolines via intramolecular radical cyclisation and heck reaction

Tetrahedron Letters

Volumn 37, Issue 15, 1996, Pages 2659-2662

  Mohanakrishnan, Arasambattu K ^a   Srinivasan, Panayencheri C ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CARBOLINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029965483     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00354-1     Document Type: Article

References (26)

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26. 3) data of some representative compounds. 7d δ 3. 5 (s, 3H), 4.2 (s, 2H), 4.9 (s, 2H), 5.8 (s, 1H), 6 (s, 1H), 7.2-8.1 (m, 14H). 8b δ 2.62-2.86 (m, 3H), 3.45 (d, 1H) 3.54 (s, 3H), 4-4.1 (m, 2H), 5.1-5.2 (d, 1H), 7.2-7.6 (m, 9H), 7.75-7.8 (m, 2H), 7.9 (m, 2H), 8.05-8.1 (d, J=7.5Hz, 1H). 8c δ 2.55 (dd, 1H), 2.9 (m, 1H), 3.1 (m, 2H), 3.85 (d, 1H), 4.06 (d, 1H), 5.15 (d, 1H), 7.2-7.6 (m, 14H), 7.8-7.85 (dd, 4H), 8.1 (d, J=7.5Hz, 1H). 10b δ 3.8 (s, 3H), 4.8 (s, 2H),4.98 (s, 2H) 6.26 (s,1H), 7.2-7.7 (m, 11H), 8 (m, 2H), 8.2 (d, J=7Hz, 1H). 10c δ 4.46 (s, 2H), 5.05 (s, 2H), 7 (s, 1H), 7.2-7.8 (m, 16H), 8 (d, 2H), 8.3 (d, J=7Hz, 1H).