Neonatal transplantation tolerance is associated with a systemic reduction in memory cells, altered chimeric cell phenotype, and modified eicosanoid and cytokine production

Transplantation

Volumn 61, Issue 8, 1996, Pages 1198-1205

  Ruiz, Phillip ^a   Nassiri, Mehdi ^a   Gregorian, Shahik ^b   Viciana, Ana L ^a   Streilein, J Wayne ^c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b GENENTECH INC   (United States)

^c SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ICOSANOID; INTERLEUKIN 2; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROSTAGLANDIN E2; THROMBOXANE A2; THROMBOXANE B2;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CHIMERA; CONTROLLED STUDY; GRAFT REJECTION; ICOSANOID METABOLISM; IMMUNOCOMPETENT CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANIMALS, NEWBORN; CELL TRANSPLANTATION; CYTOKINES; EICOSANOIDS; IMMUNE TOLERANCE; IMMUNOLOGIC MEMORY; MICE; SKIN TRANSPLANTATION; T-LYMPHOCYTES; TRANSPLANTATION CHIMERA;

EID: 0029965164     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199604270-00014     Document Type: Article

References (41)

1. Starzl TE, Demetris AJ, Trucco M, et al. Chimerism and donor-specific nonreactivity 27 to 29 years after kidney allotransplantation. Transplantation 1993; 55: 1272.
2. Suberbielle C, Calliat-Zucman S, Legendre C, et al. Peripheral microchimerism in long-term cadaveric kidney allograft recipients. Lancet 1994; 343: 1468.
3. Fontes P, Rao AS, Demetris AJ, et al. Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation. Lancet 1994; 344: 151.
4. Tomita Y, Khan A, Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen. J Immunol 1994; 153: 1087.
5. a controlled by hemopoietic cells in the thymus. J Exp Med 1990; 172: 1305.
6. + T helper precursor cells that can recognize class II MHC on injected donor lymphoid cells. J Immunol 1991; 146: 1104.
7. Ruiz P, Streilein JW. Evidence that I-E-negative mice resistant to neonatal H-2 tolerance induction display ubiquitous thymic clonal deletion of donor-reactive T cells. Transplantation 1993; 55: 321.
8. Ruiz P, Nassiri M, Viciana AL, Padmanabhan J, Streilein JW. Characterization of donor chimerism, alloreactive host T cells and memory cell development in thymi from mice resistant to neonatal transplantation tolerance. J Immunol 1995; 154: 633.
9. Nassiri M, Viciana A, Streilein JW, Ruiz P. Donor-specific skin transplants activate allodestructive T cells in mice resistant to neonatal H-2 tolerance induction. Transplantation 1993; 56: 1460.
10. Adkins B, Ghanei A, Hamilton K. Up-regulation of murine neonatal T helper cell responses by accessory cell factors. J Immunol 1994; 153: 3378.
11. Powell TJ, Streilein JW. Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells. J Immunol 1990; 144: 854.
12. Nassiri M, Viciana A, Padmanabhan J, Streilein JW, Ruiz P. Lymphoid organ production of immunomodulatory eicosanoids in mice resistant to neonatal tolerance induction. Transplantation 1994; 57: 1643.
13. Streilein JW, Klein J. Neonatal tolerance induction across regions of H-2 complex. J Immunol 1977; 119: 2147.
14. Billingham RE, Medawar P. The technique of free skin grafting in mammals. J Exp Biol 1951; 28: 385.
15. Ulius MH, Simpson E, Herzenberg LA. A rapid method for isolation of functional thymus-derived murine lymphocytes. Eur J Immunol 1973; 3: 645.
16. Klotman PE, Smith Sr, Volpp BD, Coffman TM, Yarger WE. Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. Am J Physiol 1986; 250: F282.
17. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248.
18. - mice resistant to neonatal tolerance induction. Transplant Proc 1993; 25: 368.
19. Sprent J. T and B memory cells. Cell 1994; 76: 315.
20. Mackay CR. Immunological memory. Adv Immunol 1993; 53: 217.
21. MacDonald HR, Budd RC, Cerottini JC. Pgp-1 (Ly24) as a marker of murine memory T lymphocytes. Curr Top Microbiol Immunol 1990; 159: 97.
22. Jung TM, Gallatin WM, Weissman IL, Dailey MO. Down-regulation of homing receptors after T cell activation. J Immunol 1988; 141: 4110.
23. Budd RC, Cerottini JC, Horvath C, et al. Distinction of virgin and memory T lymphocytes: Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J Immunol 1987; 138: 3120.
24. Carding SR, Hayday AC, Bottomly K. Cytokines in T-cell development. Immunol Today 1991; 12: 239.
25. Streilein JW, Socarras S, Powell TJ. Influence of I-E expression on induction of neonatal transplantation tolerance. Eur J Immunol 1990; 21: 261.
26. Nickerson P, Steurer W, Steiger J, Zheng X, Steele AW, Strom TB. Cytokines and the Th1/Th2 paradigm in transplantation. Curr Opinion Immunol 1994; 6: 757.
27. Wu CW, Demeure CE, Gately M, et al. In vitro maturation of human neonatal CD4 T lymphocytes: 1. Induction of IL-4-producing cells after long-term culture in the presence of IL-4 plus either IL-2 or IL-12. J Immunol 1994; 152: 1141.
28. Chen N, Field EH. Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance. Transplantation 1995; 59: 933.
29. Donckier V, Abramowicz D, Bruyns C, et al. IFN-γ prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice. J Immunol 1994; 153: 2361.
30. Jones LA, Chin LT, Merriam GR, Nelson LM, Krusbeck AM. Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy. J Exp Med 1990; 72: 1277.
31. Matriano JA, Socarras S, Streilein JW. Cellular mechanisms that maintain neonatally-induced tolerance of class II alloantigens. J Immunol 1994; 153: 1505.
32. Tomita Y, Nishimura Y, Harada N, et al. Evidence for involvement of clonal anergy in MHC class I class II disparate skin allograft tolerance after the termination of intrathymic clonal deletion. J Immunol 1990; 145: 4026.
33. Streilein JW. Neonatal tolerance of H-2 alloantigens: procuring graft acceptance the old-fashioned way. Transplantation 1991; 52: 1.
34. Bushell A, Pearson TC, Morris PJ, Wood KJ. Donor-recipient microchimerism is not required for tolerance induction following recipient pretreatment with donor-specific transfusion and anti-CD4 antibody. Transplantation 1995; 59: 1367.
35. Ruiz P, Rey L, Spurney R, Coffman T, Viciana A. Thromboxane augmentation of alloreactive T cell function. Transplantation 1992; 54: 498.
36. Smith KA. Interleukin-2. Curr Opinion Immunol 1992; 4: 271.
37. Jordan ML. Prostaglandins and suppression of the allograft response. Transplant Sci 1991; 1: 55.
38. 2 and other cyclic AMP elevating agents modulate IL-2 and IL-2Rα gene expression at multiple levels. J Immunol 1992; 148: 2845.
39. Kunkel SL, Chensue SW, Phan SH. Prostaglandins as endogenous mediators of interleukin-1 production. J Immunol 1986; 136: 186.
40. Tite JP, Foellmer HG, Madri JA, Janeway CA. Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen. J Immunol 1987; 139: 2892.
41. Murray JS, Madri J, Tite J, Carding SR, Bottomly K MHC control of CD4+ T cell subset activation. J Exp Med 1989; 170: 2135.