A comparison of conventional metaphase analysis of Giemsa-stained chromosomes with multi-colour fluorescence in situ hybridization analysis to detect chromosome aberrations induced by daunomycin

Mutagenesis

Volumn 11, Issue 6, 1996, Pages 537-546

  Ellard, Sian ^a,c   Toper, Sheila ^b   Stemp, Gill ^b   Parry, Elizabeth M ^a   Wilcox, Phillip ^b   Parry, James M ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c ROYAL DEVON AND EXETER HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DAUNORUBICIN;

ADULT; ARTICLE; CHROMOSOME 1; CHROMOSOME 2; CHROMOSOME 3; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME PAINTING; CONTROLLED STUDY; DRUG CARCINOGENICITY; FLUORESCENCE IN SITU HYBRIDIZATION; GIEMSA STAIN; HUMAN CELL; LYMPHOCYTE CULTURE; MALE; METAPHASE; MUTATION RATE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; TECHNIQUE;

EID: 0029964741     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/11.6.537     Document Type: Article

References (43)

1. Abella Columna, E., Giaccia, A.J., Evans, J.W., Yates, B.L. and Morgan, W.F. (1993) Analysis of restriction enzyme-induced chromosomal aberrations by fluorescence in situ hybridization. Environ. Mol. Mutagenesis, 22, 26-33.
2. Barrios, L., Miro, R., Caballin, M.R., Fuster, C., Guedea, F., Subias, A. and Egozcue, J. (1989) Cytogenetic effects of radiotherapy breakpoint distribution in induced chromosome aberrations. Cancer Genetics and Cytogenetics, 41, 61-70.
3. Bauchinger, M. and Gotz, G. (1979) Distribution of radiation induced lesions in human chromosomes and dose-effect relation analysed with G-banding. Rad. Env. Biophysics, 16, 355-366.
4. Bauchinger, M., Schmid, E., Zitzelsberger, H., Braselmann, H. and Nahrstedt, U. (1993) Radiation-induced chromosome aberrations analysed by two-colour fluorescence in situ hybridization with composite whole chromosome-specific DNA probes and a pancentromeric DNA probe. Int. J. Rad. Biol., 64, 179-184.
5. Bender, M.A., Awa, A.A., Brooks, A.L., Evans, H.J., Groer, P.G., Littlefield, L.G., Pereira, C., Preston, R.J. and Wachholz, B.W. (1988) Current status of cytogenetic procedures to detect and quantify previous exposures to radiation. Mutat. Res., 196, 103-159.
6. Buckton, K.E. (1983): Chromosome aberrations in patients treated with X-irradiation for ankylosing spondylitis. In Radiation-Induced Chromosome Damage in Man. Liss, New York, pp. 491-511.
7. Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (1989) Department of Health Report on Health and Social Subjects. 35. Guidelines for the Testing of Chemicals for Mutagenicity. 1st edn. HMSO, London, pp. 74-86.
8. Dauwerse, J.G., Wiegant, J., Raap, A.K., Breuning, M.H. and van Ommen, G.J.B. (1992) Multiple colors by fluorescence in situ hybridization using ratio-labelled DNA probes create a molecular karyotype. Hum. Mol. Genet., 1, 593-598.
9. Dutrillaux, B., Viegas-Pequinot, E., Prod'homme, M., Sportes, M. and Prieur, M. (1981) Tentative estimate of the risk of chromosomal disease due to radiation induced translocations in man. Mutat. Res., 82, 191-200.
10. Ellard, S., Parry, E.M. and Parry, J.M. (1995) Use of multi-colour chromosome painting to identify chromosomal rearrangements in human lymphocytes exposed to bleomycin: a comparison with conventional cytogenetic analysis of Giemsa-stained chromosomes. Environ. Mol. Mutagenesis, 26, 44-54.
11. Gilman, A.G., Rall, T.W., Nies, A.S. and Taylor, P. (eds) (1990) The Pharmacological Basis of Therapeutics. 8th edn. Pergammon, pp. 1241-1243.
12. 0 human lymphocytes. Mutat. Res., 307, 273-283.
13. Kano, Y. and Little, J.B. (1986) Site-specific chromosomal rearrangement induced in human diploid cells by X-irradiation. Cytogenet. Cell Genet., 41, 22-29.
14. Knehr, S., Zitzelsberger, H., Braselmann, H. and Bauchinger, M. (1994) Analysis for DNA-proportional distribution of radiation-induced chromosome aberrations in various triple combinations of human chromosomes using fluorescence in situ hybridization. Int. J. Rad. Biol., 65, 683-690.
15. Kovacs, M.S., Evans, J.W., Johnstaone, I.M. and Brown, J.M. (1994) Radiation-induced damage, repair and exchange formation in different chromosomes of human fibroblasts determined by fluorescence in situ hybridization. Rad. Res., 137, 34-43.
16. Lee, C.L.Y. and Kamra, O.P. (1981) The pattern of radiation-induced transmissible aberrations in a human cell culture. Hum. Genet., 57, 380-384.
17. Lucas, J.N., Tenjin, T., Straume, T., Pinkel, D., Moore II, D., Lilt, M. and Gray, J.W. (1989a) Rapid human chromosome aberration analysis using fluorescence in situ hybridization. Int. J. Rad. Biol., 56, 35-44.
18. Lucas, J.N., Tenjin, T., Straume, T., Pinkel, D., Moore II, D., Lilt, M. and Gray, J.W. (1989b) Erratum. Int. J. Rad. Biol., 56, 201.
19. Lucas, J.N., Awa, A., Straume, T., Poggensee, M., Kodama, Y., Nakano, O. Ohtaki, K., Weier, H.-U., Pinkel, D., Gray, J. and Littlefield, G. (1992a) Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. Int. J. Rad. Biol., 62, 53-63.
20. Lucas, J.N., Poggensee, M. and Straume, T. (1992b) The persistence of chromosome translations in a radiation worker accidentally exposed to tritium. Cytogenet. Cell Genet., 60, 255-256.
21. Lucas, J.N., Poggensee, M. and Straume, T. (1993) Translocations between two specific human chromosomes detected by three-colour 'chromosome painting'. Cytogenet. Cell Genet., 62, 11-12.
22. Matsuoka, A., Tucker, J.D., Hayashi, M., Yamazaki, N. and Sofuni, T. (1994) Chromosome painting analysis in human lymphocytes in vitro. Mutagenesis, 9, 151-155.
23. Mayall, B.H., Carrano, A.V., Moore II, D.H., Ashworth, L., Bennett, D.E. and Mendelsohn, M. (1984) The DNA-based human karyotype. Cytometry, 5, 376-385.
24. Nakano, M., Nakashima, E., Pawel, D.J., Kodama, Y. and Awa, A. (1993) Frequency of reciprocal translocations and dicentrics induced in human blood lymphocytes by X-irradiation as determined by fluorescence in situ hybridization. Int. J. Rad. Biol., 64, 565-569.
25. Natarajan, A.T., Vyas, R.C., Darroudi, F. and Vermeulen, S. (1992) Frequencies of X-ray induced chromosome translocations in human peripheral lymphocytes as detected by in situ hybridization using chromosome specific DNA libraries. Int. J. Rad. Biol., 61, 199-203.
26. Pandita, T.K., Gregoire, V., Dhingra, K. and Hittelman, W.N. (1994) Effect of chromosome size on aberration levels caused by gamma radiation as detected by fluorescence in situ hybridization. Cytogenet. Cell Genet., 67, 94-101.
27. Rabbitts, T.H. (1991) Translocations, master genes and differences between the origins of acute and chronic leukaemias. Cell, 67, 641-644.
28. Rabbitts, T.H. (1993) Chromosomal abnormalities in cancer cells: identification of molecules important for tumour development. Biochem. Soc. Trans., 21, 809-815.
29. Rabbitts, T.H. (1994) Chromosomal translocations in human cancer. Nature, 372, 143-149.
30. San Roman, C. and Bobrow, M. (1973) The sites of radiation-induced breakage in human lymphocyte chromosomes, determined by quinacrine fluorescence. Mutat. Res., 18, 325-331.
31. Savage, J.R.K. (1976) Annotation: classification and relationships of induced chromosomal structural changes. J. Med. Genet., 13, 103-122.
32. Schmid, E., Zitzelsberger, H., Braselmann, H., Gray, J.W. and Bauchinger, M. (1992) Radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization with a triple combination of composite whole chromosome-specific DNA probes. Int. J. Rad. Biol., 62, 673-678.
33. Scott, D., Danford, N., Dean, B., Kirkland, D.J. and Richardson, C. (1983) In vitro chromosome aberration assays. In Dean, B.J. (ed.), Report of U.K.E.M.S. Sub-Committee on 'Guidelines for Mutagenicity Testing' Part I. 1st edn. pp. 41-64.
34. Scott, D., Danford, N., Dean, B. and Kirkland, D.J. (1983) Metaphase chromosome aberration assays in vitro. In Kirkland, D.J. (ed.), 'Basic Mutagenicity Tests: U.K.E.M.S. Recommended Procedures' Part I, Revised. pp. 62-86.
35. Speicher, M.R., Gwyn Ballard, S. and Ward, D.C. (1996) Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nature Genet., 12, 368-375.
36. Sumner, A.T., Evans, H.J. and Buckland, R.A. (1981) New techniques for distinguishing between human chromosomes. Nature (New Biology), 232, 31-32.
37. Tanaka, K., Kamad, N., Ohkita, T. and Kuramoto, A. (1983) Nonrandom distribution of chromosome breaks in lymphocytes of atomic bomb survivors. J. Rad. Res., 24, 291-304.
38. Tewey, K.M., Chen, G.L., Nelson, E.M. and Liu, L.F. (1984) Intercalative antitumour drugs interfere with the breakage-reunion reaction of mammalian topoisomerase II. J. Biol. Chem., 259, 9182-9187.
39. Tucker, J.D. and Senft, J.R. (1994) Analysis of naturally occurring and radiation-induced breakpoint locations in human chromosomes 1, 2 and 4. Radiation Research 140, 31-36.
40. Tucker, J.D., Ramsey, M.J., Lee, D.A. and Minkler, J.L. (1993) Validation of chromosome painting as a biodosimeter in human peripheral lymphocytes following acute exposure to ionizing radiation in vitro. Int. J. Rad. Biol., 64, 27-37.
41. Tucker, J.D., Lee, D.A., Ramsey, M.J., Briner, J., Olsen, L. and Moore II, D.H. (1994) On the frequency of chromosome exchanges in a control population measured by chromosome painting. Mutat. Res., 313, 193-202.
42. Tucker, J.D., Lee, D.A. and Moore II, D.H. (1995a) Validation of chromosome painting. II. A detailed analysis of aberrations following high doses of ionizing radiation in vitro. Int. J. Rad. Biol., 67, 19-28.
43. Tucker, J.D., Morgan, W.F., Awa, A.A., Bauchinger, M., Blakey, D., Cornforth, M.N., Littlefield, L.G., Natarajan, A.T. and Shasserre, C. (1995b) A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenet. Cell Genet., 68, 211-221.