Maturation of human intestinal lactase-phlorizin hydrolase Generation of the brush border form of the enzyme involves at least two proteolytic cleavage steps

European Journal of Biochemistry

Volumn 236, Issue 3, 1996, Pages 789-795

  Jacob, Ralf ^a   Radebach, Ilona ^a   Wüthrich, Marcel ^b   Grünberg, Jürgen ^b   Sterchi, Erwin E ^b   Naim, Hassan Y ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Dibasic sites; Intestine; Intracellular extracellular cleavage; Lactase phlorizin hydrolase; Mutagenesis

Indexed keywords

DISACCHARIDASE; GLYCOSYLCERAMIDASE; LACTASE;

ANIMAL CELL; ARTICLE; BRUSH BORDER; CELL MATURATION; CONTROLLED STUDY; DOG; ENZYME ACTIVATION; GENE EXPRESSION; HAMSTER; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; KIDNEY CELL; MOLECULAR CLONING; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SMALL INTESTINE;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BASE SEQUENCE; CELL LINE; CHO CELLS; CODON; CRICETINAE; DOGS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; ENZYME PRECURSORS; GLYCOSYLCERAMIDASE; HUMANS; INTESTINAL MUCOSA; INTESTINE, SMALL; KIDNEY; MICROVILLI; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA; CANIS FAMILIARIS; CRICETINAE;

EID: 0029964611     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.t01-1-00789.x     Document Type: Article

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