Effect of cilostazol on the production of platelet-derived growth factor in cultured human vascular endothelial cells

Biochemical and Molecular Medicine

Volumn 57, Issue 2, 1996, Pages 156-158

  Mizutani, Masakazu ^a,b   Okuda, Yukichi ^a   Yamashita, Kamejiro ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; CILOSTAZOL; PLATELET DERIVED GROWTH FACTOR;

ARTERIOSCLEROSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC MICROANGIOPATHY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PROTEIN SYNTHESIS INHIBITION; VASCULAR ENDOTHELIUM;

EID: 0029964604     PISSN: 10773150     EISSN: None     Source Type: Journal    
DOI: 10.1006/bmme.1996.0023     Document Type: Article

References (22)

1. Yorek, MA, Dunlap, JA. The effect of elevated glucose levels on myo-inositol metabolism in cultured bovine aortic endothelial cells. Metab Clin Exp 38:16-22, 1989.
2. Lorenzi, M, Cagliero, E, Toledo, S. Glucose toxicity for human endotheliai cells in culture: delayed replication, disturbed cell cycle, and accelerated death. Diabetes 34:621-627, 1985.
3. Stout, RW. Glucose inhibits replication of cultured human endothelial cells. Diabetologia 23:436-439, 1982.
4. Lorenzi, M, Montisano, F, Toledo, S, Barrieux, A. High glucose induces DNA damages in cultured human endothelial cells. J Clin Invest 77:322-325, 1986.
5. +)-ATPase inhibition in aortic wall of rabbits. Diabetologia 32:402-408, 1989.
6. Brownlee, M, Vlassara, H, Cerami, A. Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med 101:527-537, 1984.
7. Wohaieb, SA, Godin, DV. Alterations in free radical tissuedefense mechanisms in streptozotocin-induced diabetes in rat. Effects of insulin treatment. Diabetes 36:1014-1018, 1987.
8. Report of a WHO Study Group. Diabetes mellitus. Tech Rep Series 727:58-67, 1985.
9. Ross, R. The pathogenesis of atherosclerosis - An update. N Engl J Med 314:488-500, 1986.
10. Barrett, TB, Benditt, EP. sis (platelet-derived growth factor B chain) gene transcript levels are elevated in human atherosclerotic lesions compared to normal artery. Proc Natl Acad Sci USA 84:1099-1103, 1987.
11. Mizutani, M, Okuda, Y, Yamaoka, T, Tsukahara, K, Isaka, M, Bannai, C, Yamashita, K. High glucose and hyperosmolarity increase platelet-derived growth factor mRNA levels in cultured human vascular endothelial cells. Biochem Biophys Res Commun 187:664-669, 1992.
12. Okuda, Y, Kimura, Y, Yamashita, K. Cilostazol. Cardiovas Drug Rev 11:451-465, 1993.
13. Okuda, Y, Mizutani, M, Ikegami, T, Ueno, E, Yamashita, K. Hemodynamic effect of cilostazol on peripheral artery in patients with diabetic neuropathy. Arzneimittel-Forschung/ Drug Res 42(I):4, 540-542, 1992.
14. Jaffe, EA, Nachman, RL, Becker, CG, Minick, CR. Culture of human endothelial cells derived from umbilical veins: Identification by morphologic and immunologic criteria. J Clin Invest 52:2745-2756, 1973.
15. Hsieh, H, Frangos, JA. Shear stress increases endothelial platelet-derived growth factor mRNA levels. Am J Physiol 260: (Heart Circ Physiol 29), H642-H646, 1991.
16. Kourembanas, S, Faller, DV. Oxygen tension regulates the expression of the platelet-derived growth factor-B chain in human endothelial cells. J Clin Invest 86:670-674, 1990.
17. Daniel, TO, Gibbs, VC, Milfay, DC, Williams, LT. Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta. J Biol Chem 261:9579-9582, 1986.
18. Daniel, TO, Gibbs, VC, Milfay, DC, Williams, LT. Thrombin stimulates c-sis gene expression in microvascular endothelial cells. J Biol Chem 262:11893-11896, 1987.
19. Albelda, SM, Kern, JA. Endotoxin stimulates plateletderived growth factor production from cultured human pulmonary endothelial cells. Am J Physiol 257: (Lung Cell Mol Physiol 1), L65-L70, 1987.
20. Starksen, NF, Harsh, GR, Gibbs, VC, Williams, LT. Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells. J Biol Chem 262:14381-14384, 1987.
21. Fox, PL, DiCorleto, PE. Regulation of production of a platelet-derived growth factor-like protein by cultured bovine aortic endothelial cells. J Cell Physiol 121:298-308, 1984.
22. King, GL et al. Characterization of the effects of insulin, IGF and hyperglycemia on the metabolism and functions of vascular endothelial cells. In Problems in Methodology and Clinical Aspects, Basel: Karger, 1990, p. 86.