Cerebrospinal fluid from multiple sclerosis patients inactivates neuronal Na+ current

Brain

Volumn 119, Issue 2, 1996, Pages 457-463

  Köller, Hubertus ^a   Buchholz, Jochen ^a   Siebler, Mario ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Cerebrospinal fluid; Cytokines; Multiple sclerosis; Neuronal cell culture; Sodium current

Indexed keywords

IMMUNOGLOBULIN G; SODIUM ION;

ADULT; ARTICLE; BRAIN CELL; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; EXCITABILITY; FEMALE; HEAT; HUMAN; MALE; MEMBRANE CURRENT; MULTIPLE SCLEROSIS; NERVE CELL CULTURE; NERVE CELL NETWORK; PRIORITY JOURNAL; SODIUM CURRENT; SYMPTOM;

EID: 0029964252     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/119.2.457     Document Type: Article

References (47)

1. Ahmed Z. Expression of membrane currents in rat neocortical neurons in serum-free culture. I. Inward currents. Brain Res 1988a; 468: 285-95.
2. Ahmed Z. Expression of membrane currents in rat neocortical neurons in serum-free culture. II. Outward currents. Brain Res 1988b; 468: 297-305.
3. Bomstein MB, Grain SM. Functional studies of cultured brain tissues as related to 'demyelinative disorders'. Science 1965; 148: 1242-4.
4. Bottenstein JE, Sato GH. Growth of rat neuroblastoma cell line in serum-free supplemented medium. Proc Natl Acad Sci USA 1979; 76: 514-17.
5. + channel blocking factor in the cerebrospinal fluid. Pflugers Arch 1992; 421: 552-7.
6. Brinkmeier H, Wollinsky KH, Seewald MJ, Hülser PJ, Mehrkens HH, Kornhuber HH, et al. Factors in the cerebrospinal fluid of multiple sclerosis patients interfering with voltage-dependent sodium channels. Neurosci Lett 1993; 156: 172-5.
7. Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions [see comments]. Ann Neurol 1995; 37: 424-35.
8. Franciotta DM, Grimaldi LME, Martino GV, Piccolo G, Bergamaschi R, Citterio A, et al. Tumor necrosis factor in serum and cerebrospinal fluid of patients with multiple sclerosis. Ann Neurol 1989; 26: 787-9.
9. Gallo P, Piccinno M, Pagni S, Tavolato B. Interleukin-2 levels in serum and cerebrospinal fluid of multiple sclerosis patients. Ann Neurol 1988; 24: 795-7.
10. Gallo P, Piccinno MG, Tavolato B, Siden A. A longitudinal study on IL-2, SIL-2R, EL-4 and IFN-gamma in multiple sclerosis CSF and serum. J Neurol Sci 1991; 101: 227-32.
11. Hamill OP, Marry A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 1981; 391: 85-100.
12. Hartung HP. Immune-mediated demyelination [see comment]. [Review]. Ann Neurol 1993; 33: 563-7. Comment on: Ann Neurol 1993; 33: 591-6.
13. Hartung HP. Immune-mediated demyelination [see comment]. [Review]. Ann Neurol 1993; 33: 563-7. Comment on: Ann Neurol 1993; 33: 591-6.
14. Hartung HP, Jung S, Stoll G, Zielasek J, Schmidt B, Archelos JJ, et al. Inflammatory mediators in demyelinating disorders of the CNS and PNS. [Review]. J Neuroimmunol 1992; 40: 197-210.
15. Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA. Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology 1990; 40: 1735-9.
16. Hille B, Mechanisms of block. In: Hille B, editor. Ionic channels of excitable membranes. 2nd ed. Sunderland (MA): Sinauer, 1992: 390-422.
17. Hofman FM, Hinton DR, Johnson K, Merrill JE. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989; 170: 607-12.
18. + channels: no evidence for the involvement of the IL-2 receptor. Pflügers Arch 1994; 426: 61-7.
19. 4. Brain Res 1993; 628: 313-16.
20. + conductance inhibitor. Brain Res 1993; 612: 28-34.
21. Koller H, Buchholz J, Siebler M. Bacterial endotoxins impair electrophysiological properties of cultured astrocytes but not of cultured neurons. J Neurol Sci 1994a; 124: 156-62.
22. 4induce independently regulated electrophysiological and immunological responses in cultured astrocytes. J Neuroimmunol 1994b; 55: 179-85.
23. Maimone D, Gregory S, Amason BGW, Reder AT. Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis. J Neuroimmunol 1991; 32: 67-74.
24. McDonald WI. The dynamics of multiple sclerosis. J Neurol 1993; 240: 28-36.
25. Numann R, Catterall WA, Scheuer T. Functional modulation of brain sodium channels by protein kinase C phosphorylation. Science 1991; 254: 115-18.
26. Plata-Salamán CR, ffrench-Mullen JMH. Interleukin-2 modulates calcium currents in dissociated hippocampal CA1 neurons. Neuroreport 1993; 4: 579-81.
27. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13: 227-31.
28. + channels by local anesthetics. Science 1994; 265: 1724-8.
29. Rasminsky M, Sears TA. Internodal conduction in undissected demyelinated nerve fibres. J Physiol (Lond) 1972; 227: 323-50.
30. + conductance in an identified neuron of Aplysia kurodai. Neurosci Lett 1990; 115: 219-25.
31. + conductance by tumor necrosis factor in identified neurons of Aplysia kurodai. J Neurosci Res 1991; 28: 466-73.
32. Schauf CL, Davis FA, Sack DA, Reed BJ, Kesler RL. Neuroelectric blocking factors in human and animal sera evaluated using the isolated frog spinal cord. J Neurol Neurosurg Psychiatry 1976; 39: 680-5.
33. Schauf CL, Schauf V, Davis FA, Mizen MR. Complement-dependent serum: neuroelectric blocking activity in multiple sclerosis. Neurology 1978; 28: 426-30.
34. Schauf CL, Pencek TL, Davis FA, Rooney MW. Physiologic basis for neuroelectric blocking activity in multiple sclerosis. Neurology 1981; 31: 1337-41.
35. Seil FJ. Tissue culture studies of demyelinating disease: a critical review. Ann Neurol 1977; 2: 345-55.
36. Seil FJ, Leiman AL, Kelly JM 3d. Neuroelectric blocking factors in multiple sclerosis and normal human sera. Arch Neurol 1976; 33: 418-22.
37. Sharief MK, Hentges R. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis [see comments]. N Engl J Med 1991; 325: 467-72. Comment in: N Engl J Med 1992; 326: 272-3.
38. Sharief MK, Hentges R. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis [see comments]. N Engl J Med 1991; 325: 467-72. Comment in: N Engl J Med 1992; 326: 272-3.
39. Stichel CC, Müller HW. Expression of inherent neuronal shape characteristics after transient sensitivity to epigenetic factors. Brain Res Dev Brain Res 1992; 68: 149-62.
40. Thompson AJ, McDonald WI. Multiple sclerosis and its pathophysiology. In: Asbury AK, McKhann GM, McDonald WI, editors. Diseases of the nervous system, clinical neurobiology. 2nd ed. Philadelphia: W. B. Saunders, 1992: 1209-28.
41. Tsukada N, Miyagi K, Matsuda M, Yanagisawa N, Yone K. Tumor necrosis factor and interleukin-1 in the CSF and sera of patients with multiple sclerosis. J Neurol Sci 1991; 104: 230-4.
42. Van den Berg RJ, Kok P, Voskuyl RA. Valproate and sodium currents in cultured hippocampal neurons. Exp Brain Res 1993; 93: 279-87.
43. Weller M, Stevens A, Sommer N, Melms A, Dichgans J, Wiethölter H. Comparative analysis of cytokine patterns in immunological, infectious, and oncological neurological disorders. J Neurol Sci 1991; 104: 215-21.
44. Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA. T-cell receptor Vα-Vβ repertoire and cytokine gene expression in active multiple sclerosis lesions. J Exp Med 1992; 175: 993-1002.
45. Yokota T, Saito Y, Miyatake T. Conduction slowing without conduction block of compound muscle and nerve action potentials due to sodium channel block. J Neurol Sci 1994; 124: 220-4.
46. Youl BD, Turano G, Miller DH, Towell AD, MacManus DG, Moore SG, et al. The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. Brain 1991; 114: 2437-50.
47. Zubov AN, Pisareva LN, Salnikov KV. The action of blood serum and its components on potential-dependent sodium channels in neuroblastoma cells. Gen Physiol Biophys 1991; 10: 321-32.