Role of endothelin-1 in repeated electrical stimulation-induced microcirculatory disturbance and mucosal damage in rat stomach

Journal of Gastroenterology and Hepatology (Australia)

Volumn 11, Issue 3, 1996, Pages 279-285

  Fukumura, Dai ^a   Kurose, Iwao ^a   Miura, Soichiro ^a   Serizawa, Hiroshi ^a   Sekizuka, Eiichi ^a   Nagata, Hiroshi ^a   Tsuchiya, Masaharu ^a   Ishii, Hiromasa ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Endothelin receptors; Gastric ulcer; Intravital microscopy; Laser Doppler velocimeter

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; INTRAVENOUS DRUG ADMINISTRATION; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; STOMACH MUCOSA BLOOD FLOW; STOMACH MUCOSA LESION; STOMACH ULCER;

EID: 0029964031     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1996.tb00076.x     Document Type: Article

References (21)

1. Kurose I, Miura S, Fukumura D et al. Attenuating effect of antithrombin III on the fibrinolytic activation and microvascular derangement in rat gastric mucosa. Thromb. Haemost. 1994; 71: 119-23.
2. Kurose I, Fukumura D, Miura S et al. Fluorographic study on the oxidative stress in the process of gastric mucosal injury: Attenuating effect of vitamin E. J. Gastroenterol. Hepatol. 1993; 8: 254-8.
3. Kurose I, Suematsu M, Miura S et al. Involvement of superoxide anion and platelet-activating factor in increased tissue-type plasminogen activator during rat gastric microvascular damages. Thromb. Res. 1991; 62: 241-8.
4. Yanagisawa M, Kurihara H, Kimura S et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-15.
5. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990; 348: 730-2.
6. Sakurai T, Yanagisawa M, Takuwa Y et al. Cloning of non-isopeptide selective subtype of endothelin receptor. Nature 1990; 348: 732-5.
7. Masaki T. Tissue specificity of the endothelin-induced responses. J. Cardiovasc. Pharmacol. 1991; 17 (Suppl. 7): S1-4.
8. Whittle BJR, Payne AN, Esplugues JV. Cardiopulmonary and gastric ulcerogenic actions of endothelin-1 in the guinea pig and rat. J. Cardiovasc. Pharmacol. 1989; 13 (Suppl. 5): S103-7.
9. Miura S, Kurose I, Fukumura D et al. Ischemic bowel necrosis by endothelin-1: An experimental model in rats. Digestion 1991; 48: 163-72.
10. Miyauchi T, Yanagisawa M, Tomizawa T et al. Increased plasma concentration of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet 1989; ii: 53-4.
11. Toyo-oka T, Aizawa T, Suzuki N et al. Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris. Circulation 1991; 83: 476-83.
12. Firth JD, Ratcliffe PJ, Raine AEG, Ledingham JGG. Endothelin: An important factor of acute renal failure? Lancet 1988; ii: 1179-81.
13. Kurose I, Miura S, Fukumura D et al. Role of platelet-activating factor on the fibrinolytic activation in the pathogenesis of gastric mucosal damage induced by endothelin-1. Gut 1992; 33: 868-71.
14. Wallace JL, Keenan CM, MacNaughton WK, McKnight GW. Comparison of the effects of endothelin-1 and endothelin-3 on the rat stomach. Eur. J. Pharmacol. 1989; 167: 41-7.
15. Leung FW, Morishita T, Livingstone EH, Reedy T, Guth PH. Reflectance spectrophotometry for the assessment of gastroduodenal mucosal perfusion. Am. J. Physiol. 1987; 252: G797-804.
16. Morishita T, Guth PH. Effect of exogenous acid on the rat gastric mucosal microcirculation in haemorrhagic shock. Gastroenterology 1987; 82: 1958-64.
17. Suzuki N, Matsumoto H, Kitada C, Masaki T, Fujino M. A sensitive sandwich-enzyme immunoassay for human endothelin. J. Immunol. Methods 1989; 118: 245-50.
18. A) antagonist isolated from Streptomyces misakiensis. Biochem. Biophys. Res. Commun. 1991; 178: 132-7.
19. A receptor. Life Sci. 1992; 50: 247-55.
20. Suzuki N, Miyauchi T, Tomobe Y et al. Plasma concentrations of endothelin-1 in spontaneously hypertensive rats and DOCA-salt hypertensive rats. Biochem. Biophys. Res. Commun. 1990; 167: 941-7.
21. Nakamura M, Oda M, Inoue J et al. Binding sites of endothelin-1 and 3 on rat mesentery, stomach and large intestine: Radioautographic investigation. In: Tsuchiya M, Asano M, Katori M, eds. Microcirculation annual 1991. Tokyo: Nihon-Igakukan, 1991; 71-2.