Identification and determination of 3,4-dihydroxyphenylacetaldehyde, the dopamine metabolite, in in vivo dialysate from rat striatum

Journal of Neurochemistry

Volumn 66, Issue 4, 1996, Pages 1510-1517

  Colzi, A ^a   Musolino, A ^a   Iuliano, A ^a   Fornai, F ^a   Bonuccelli, U ^a   Corsini, G U ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

3,4 Dihydroxyphenylacetaldehyde; Aldehyde dehydrogenase; Brain dialysis; Dopamine; Dopamine metabolism; Monoamine oxidase

Indexed keywords

3,4 DIHYDROXYPHENYLACETALDEHYDE; 3,4 DIHYDROXYPHENYLACETIC ACID; AMINE OXIDASE (FLAVIN CONTAINING); UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CORPUS STRIATUM; COULOMETRY; DIALYSATE; DOPAMINE METABOLISM; MALE; MICRODIALYSIS; NERVE DEGENERATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

ANIMALIA; GYMNOMYZA SAMOENSIS;

EID: 0029963623     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66041510.x     Document Type: Article

References (25)

1. Bocchetta A., Piccardi M. P., Del Zompo M., Pintus S., and Corsini G. U. (1985) 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correspondence of its binding sites to monoamine oxidase in rat brain, and inhibition of dopamine oxidative deamination in vivo and in vitro. J. Neurochem. 45, 673-676.
2. Cesura A. M. and Pletscher A. (1992) The new generation of monoamine oxidase inhibitors. Prog. Drug Res. 38, 171-297.
3. Cohen G. (1976) Alkaloid products in the metabolism of alcohol and biogenic amines. Biochem. Pharmacol. 25, 1123-1128.
4. Colzi A., D'Agostini F., Kettler R., Borroni E., and Da Prada M. (1990) Effect of selective and reversible MAO inhibitor on dopamine outflow in rat striatum: a microdialysis study. J Neural Transm. Suppl. 32, 79-84.
5. Colzi A., D'Agostini F., Cesura A. M., Borroni E., and Da Prada M. (1993) Monoamine oxidase - A inhibitors and dopamine metabolism in rat caudatus: evidence that an increased cytosolic level of dopamine displaces reversible monoamine oxidase - A inhibitors in vivo. J. Pharmacol. Exp. Ther. 265, 103-111.
6. Corsini G. U., Zuddas A., Bonuccelli U., Schinelli S., and Kopin I. J. (1987) 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by ethanol and acetaldehyde. Life Sci. 40, 827-832.
7. Davis V. E. and Walsh M. J. (1970) Alcohol, amines and alkaloids: possible biochemical basis for alcohol addiction. Science 167, 1005-1007
8. Di Chiara G. (1990) In vivo brain dialysis of neurotransmitters. Trends Pharmacol. Sci 1, 55-67.
9. Garrett M. C. and Soares-Da Silva P. (1990) Role of type A and B monoamine oxidase in the formation of 3,4-dihydroxyphenyl-acetic acid (DOPAC) in tissues from the brain of the rat. Neuropharmacology 29, 875-879.
10. 3H]DOPA in various regions of the brain. J Neurochem. 13, 655-699.
11. Hauptlorenz S., Esterbauer H., Moll W., Pumpel R., Schauenstein E., and Puschendorf B. (1985) Effects of the lipid-peroxidation product 4-hydroxynonenal and related aldehydes on proliferation and viability of cultured Ehrlich ascites tumor cells. Biochem. Pharmacol. 34, 3803-3809.
12. Hedges S. H., Herbert R. B., Knagg E., and Pasupathy V. (1988) The implication of phenyl-acetaldehydes in the biosynthesis of the phenanthro-indolizidine alkaloid, thilophorine. Tetrahedron Lett. 29, 807-810.
13. Helander A and Tottmar O. (1987) Metabolism of biogenic aldehydes in isolated human blood cells, platelets and plasma. Biochem. Pharmacol. 36, 1077-1082.
14. Jennet R. B., Tuma D. S., and Sorrel M. F. (1980) Effect of ethanol and its metabolites on microtubule formation. Pharmacology 21, 363-368.
15. Kopin I. J. (1985) Catecholamine metabolism: basic aspects and clinical significance. Pharmacol. Rev. 37, 333-364.
16. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
17. Mattammal M. B., Chung H. D., and Strong R. (1993) Confirmation of a dopamine metabolite in parkinsonian brain tissue by gas chromatography-mass spectrometry. J. Chromatogr. 614, 205-212.
18. Miglietta A., Olivero A., Gadoni E., and Gabriel L. (1991) Effects of some aldehydes on brain microtubular protein. Chem. Biol. Interact. 78, 183-191.
19. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd edit. Academic Press, San Diego.
20. Schauenstein E., Esterbauer H., and Zollner H. (1977) Aldehydes in Biological Systems (Lagnado J. R., ed), p. 1. Pion, London.
21. + by dopamine neurons is required for MPTP toxicity: studies in brain synaptosomes and PC12 cells, in MPTP: A Neurotoxin Producing a Parkinsonian Syndrome (Markey S. P., Castagnoli N., Trevor A. J., and Kopin I. J., eds), pp. 191-201. Academic Press, Orlando.
22. Soares Da Silva P. and Garrett M. C. (1990) A kinetic study of the rate of formation of dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the brain of the rat: implications for the origin of DOPAC. Neuropharmacology 29, 869-874.
23. Sodum R. S. and Chung F. L. (1991 ) Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal. Cancer Res. 51, 137-143.
24. Strong R., Wood W. G., and Burke W. J., eds (1988) Aging, Vol. 33: Central Nervous System Disorders of Aging: Clinical Intervention and Research. Raven Press, New York.
25. Tabakoff B. (1977) Brain aldehyde dehydrogenases and reductases, in Biochemistry and Function of Monoamine Enzymes (Weaver N. and Youdim M. B. H., eds), pp. 629-649. Marcel Dekker, New York.