Effect of diacetyl rhein on the development of experimental osteoarthritis. A biochemical investigation

Osteoarthritis and Cartilage

Volumn 4, Issue 4, 1996, Pages 251-261

  Carney, S L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Diacetylrhein; Osteoarthritis

Indexed keywords

DIACETYLRHEIN;

ANIMAL EXPERIMENT; ARTICLE; CARTILAGE; CONTROLLED STUDY; DOG; ORAL DRUG ADMINISTRATION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEOGLYCAN SYNTHESIS;

EID: 0029963463     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1063-4584(05)80103-7     Document Type: Article

References (37)

1. Carney SL Targets for drug discovery in osteoarthritis Drug News Perspectives 6 1993 69 77
2. Ghosh P Wells C Smith M Hutadilok N Chondroprotection, myth or reality: An experimental approach Semin Arthritis Rheum 19 4,Suppl. 1 1990 3 9
3. Huskisson E Clinical aspects of chondroprotection Semin Arthritis Rheum 194 Suppl 1 1990 30 32
4. Nguyen M Dougados M Berdah L Amor B Diacerhein in the treatment of osteoarthritis of the hip Arthritis Rheum 37 1994 529 536
5. Floridi A Castiglione S Bianchi C Mancini A Effect of rhein on the glucose metabolism of Ehrlich ascites tumor cells Biochem Pharm 40 1990 217 222
6. Castiglione S Fanciulli M Bruno T Evangelista M Del Carlo C Paggi MG Chersi A Floridi A Rhein inhibits glucose uptake in Ehrlich ascites tumor cells by alteration of membrane-associated functions Anti-Cancer Drugs 4 1993 407 414
7. Castiglione S Paggi MG Delino A Zeuli M Floridi A Inhibition of protein synthesis in neoplastic cells by rhein Biochem Pharm 40 1990 967 973
8. Raimondi L Banchelli Soldaini G Buffoni F Ignesti G Massacesi L Amaducci L Friedmann CA Rhein and derivatives. In vitro studies on their capacity to inhibit certain proteases Pharmacol Res Commun 14 1982 103 112
9. Nijs G de Witte P Geboes K Lemli J Influence of rhein anthrone and rhein on small intestine transit rate in rats; evidence of prostaglandin mediation Eur J Pharmacol 218 1992 199 203
10. Yagi T Miyawaki Y Nishikawa A Yamauchi K Kuwano S Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by indomethacin in rats J Pharm Pharmacol 45 1991 307 310
11. Carrabba M Mele G Chevellard M Angelini M Diacereine: an original approach in the treatment of degenerative and/or extra-articular rheumatism Minerva Med 78 1987 179 185
12. Mazzaro C Boccheri E Tesolin GF Ventre L Romagnoli A Clinical evaluation of diacerein in the treatment of osteoarthrosis Minerva Med 80 1989 1025 1027
13. Mazieres B Berdah L Effect of diacerhein (ART50) on an experimental post-contusive model of osteoarthritis [Abstract] Osteoarthritis Cart 1 1993 47
14. Meacock SCR Bodmer JL Billingham MEJ Experimental osteoarthritis in guinea-pigs J Exp Path 71 1990 279 293
15. Bendele AM Hulman JF Spontaneous cartilage degeneration in guinea pigs Arthritis Rheum 31 1988 561 565
16. 35S)-proteoglycan turnover products of cartilage explant cultures from dogs with experimental osteoarthritis J Orthop Res 3 1985 140 147
17. Hardingham TE Venn G Bayliss MT Chondrocyte responses in cartilage and in experimental osteoarthritis Br J Rheumatol 30 1991 32 37
18. Carney SL Billingham MEJ Caterson B Ratcliffe A Bayliss MT Hardingham TE Muir H Changes in proteoglycan turnover in experimental canine osteoarthritic cartilage Matrix 12 1992 137 147
19. Caterson B Mahmoodian J Sorrell JM Hardingham TE Bayliss MT Carney SL Ratcliffe A Muir H Modulation of native chondroitin sulphate structure in tissue development and in disease J Cell Sci 97 1990 411 417
20. Adams ME Billingham MEJ Muir H The glycosaminoglycans in menisci in experimental and natural osteoarthritis Arthritis Rheum 26 1983 69 76
21. Sandy JD Adams ME Billingham MEJ Plaas A Muir H In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis Arthritis Rheum 27 1984 388 397
22. Carney SL Billingham MEJ Muir H Sandy JD Demonstration of increased proteoglycan turnover in cartilage explants from dogs with experimental osteoarthritis J Orthop Res 2 1984 201 206
23. Bitter T Muir H A modified uronic acid carbazole reaction Anal Biochem 4 1962 330 334
24. Carney SL Proteoglycans MF Chaplin JF Kennedy Carbohydrate Analysis. A Practical Approach 2nd ed. 1994 IRL Press 125 180
25. Stegemann H Stalder K Determination of hydroxyproline Clin Chim Acta 18 1967 267 273
26. Carney SL Osborne DJ The separation of chondroitin sulfate disaccharides and hyaluronan oligosaccharides by capillary zone electrophoresis Anal Biochem 195 1991 132 140
27. Friedmann CA Structure-activity relationships of anthraquinones in some pathological conditions Pharmacology 20 Suppl 1 1980 113 122
28. Neuman M Clinical, biological and gastric fibroscopic tolerance of a new non-steroidal anti-inflammatory analgesic, diacetylrhein (Artrodar) Drugs Exp Clin Res 6 1980 262 264
29. Pomarelli P Berti M Gatti MT Mosconi P A non-steroidal anti-inflammatory drug that stimulates prostaglandin release Il Farmaco Ed Sci 35 1980 836 842
30. Yu LP Smith GN Brandt KD Myers SL O'Connor BL Brandt DA Reduction of the severity of canine osteoarthritis by prophylactic treatment with oral doxycycline Arthritis Rheum 35 1992 1150 1159
31. Wolfle D Schmute C Westendorf J Marquardt H Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes Cancer Research 50 1990 6540 6544
32. Chesis PL Levin DE Smith MT Ernster L Ames BN Mutagenicity of quinones: pathways of metabolic activation and detoxification Proc Nat Acad Sci USA 81 1984 1696 1700
33. Mian M Fratta D Rainaldi G Simi S Mariani T Benetti D Gervasi PG Superoxide anion production and toxicity in V79 cells of six hydroxy-anthraquinones Anti-Cancer Res 11 1991 1071 1076
34. Brown JP A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds Mutation Res 75 1989 243 277
35. Osborne D Woodhouse S Meacock R Early changes in the sulfation of chondroitin in guinea-pig articular cartilage, a possible predictor of osteoarthritis Osteoarthritis Cart 2 1994 215 223
36. Carney SL Hicks CA Tree B Broadmore RJ An in vivo investigation of the effect of anthraquinones on the turnover of aggrecans in spontaneous osteoarthritis in the guinea pig Inflamm Res 44 1995 182 186
37. Williams JM Ongchi DR Thonar EJ-M Repair of articular cartilage injury following intra-articular chymopapain-induced matrix proteoglycan loss J Orthop Res 11 1993 705 716