Electrical properties of neocortical neurons in slices from children with intractable epilepsy

Journal of Neurophysiology

Volumn 75, Issue 2, 1996, Pages 931-939

  Tasker, Jeffrey G ^a   Hoffman, Neil W ^b   Kim, Yang I ^c   Fisher, Robin S ^e   Peacock, Warwick J ^e   Dudek, F Edward ^d  

^a Tulane University   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Korea University College of Medicine   (South Korea)

^d Department of Ecosystem Science and Sustainability   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCYTIN; CALCIUM ION; SODIUM ION;

ADOLESCENT; ARTICLE; CALCIUM CURRENT; CHILD; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; INFANT; INTRACTABLE EPILEPSY; MALE; NEOCORTEX; NERVE CELL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REPOLARIZATION; SODIUM CURRENT; SPIKE WAVE; VOLTAGE CLAMP;

EID: 0029963277     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.75.2.931     Document Type: Article

References (28)

1. AVOLI, M. AND OLIVIER, A. Electrophysiological properties and synaptic responses in the deep layers of the human epileptogenic neocortex in vitro. J. Neurophysiol. 61: 589-606, 1989.
2. CHAGNAC-AMITAI, Y. AND CONNORS, B. W. Horizontal spread of synchronized activity in neocortex and its control by GABA-mediated inhibition. J. Neurophysiol. 61: 747-758, 1989a.
3. CHAGNAC-AMITAI, Y. AND CONNORS, B. W. Synchronized excitation and inhibition driven by intrinsically bursting neurons in neocortex. J. Neurophysiol. 62: 1149-1162, 1989b.
4. CHRISTIAN, E. P AND DUDEK, F. E. Electrophysiological evidence from glutamate microapplications of local excitatory circuits in the CA1 area of rat hippocampal slices. J. Neurophysiol. 59: 110-123, 1988.
5. CHUGANI, H. T., SHEWMON, M. D., PEACOCK, W. J., SHIELDS, W. D., MAZZIOTTA, J C., AND PHELPS, M. E. Surgical treatment of intractable neonatalonset seizures: The role of positron emission tomography. Neurology 38: 1178-1188, 1988.
6. CONNORS, B. W. Initiation of synchronized neuronal bursting in neocortex. Nature Lond. 310: 685-687, 1984.
7. CONNORS, B. W., GUTNICK, M. J., AND PRINCE, D. A. Electrophysiological properties of neocortical neurons in vitro. J. Neurophysiol. 48: 1302-1319, 1982.
8. B receptor-mediated responses in neocortex of rat and cat. J. Physiol. Lond. 406: 443-468, 1988.
9. FOEHRING, R. C., LORENZON, N. M., HERRON, P., AND WILSON, C. J. Correlation of physiologically and morphologically identified neuronal types in human association cortex in vitro J. Neurophysiol. 66: 1825-1837, 1991.
10. FRIEDMAN, A. AND GUTNICK, M. J. Low-threshold calcium electrogenesis in neocortical neurons. Neurosci. Lett. 81: 117-122, 1987.
11. HOFFMAN, N. W., TASKER, J. G., KIM, Y. I., PEACOCK, W. J., FISHER. R. S., AND DUDEK, F. E. Electrophysiological characterization of anatomically identified neurons in cortical slices from pediatric patients with intractable epilepsy (Abstract). Epilepsia 30: 733, 1989.
12. HORIKAWA, K. AND ARMSTRONG, W. E. A versatile means of intracellular labeling : injection of biocytin and its detection with avidin conjugates. J. Neurosci. Methods 25: 1-11, 1988.
13. + conductances in rat neocortical neurons: appearance of a slowly inactivating component. J. Neurophysiol. 59: 778-793, 1988.
14. KAWAGUCHI, Y. AND MAMA, K. Physiological heterogeneity of nonpyramidal cells in rat hippocampal CA1 region. Exp. Brain Res. 72: 494-502, 1988.
15. KNOWLES, W. D., AWAD, I. A., AND NAYEL, M. H. Differences of in vitro electrophysiology of hippocampal neurons from epileptic patients with mesiotemporal sclerosis versus structural lesions. Epilepsia 33: 601-609, 1992.
16. KRIEGSTEIN, A. R., SUPPES, T., AND PRINCE, D. A. Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro. Brain Res. 431: 161-171, 1987.
17. MCCORMICK, D. A. GABA as an inhibitory neurotransmitter in human cerebral cortex. J. Neurophysiol. 62: 1018-1027, 1989.
18. MCCORMICK, D. A., CONNORS, B. W., LIGHTHALL, J. W., AND PRINCE, D. A. Comparative electrophysiology of pyramidal and sparsely spiny stellate neurons of the neocortex. J. Neurophysiol. 54: 782-806, 1985.
19. MCCORMICK, D. A. AND PRINCE, D. A. Post-natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones. J. Physiol. Lond. 393: 743-762, 1987.
20. MILES, R. AND WONG, R. K. S. Inhibitory control of local excitatory circuits in the guinea-pig hippocampus. J. Physiol. Lond. 388: 611-629, 1987.
21. SAYER, R. J., BROWN, A. M., SCHWINDT, P. C., AND CRILL, W. E. Calcium currents in acutely isolated human neocortical neurons. J. Neurophysiol. 69: 1596-1606, 1993.
22. SCHWARTZKROIN, P. A. AND MATHERS, L. H. Physiological and morphological identification of a nonpyramidal hippocampal cell type. Brain Res. 157: 1-10, 1978.
23. SUTOR, B. AND ZIEGLGANSBERGER, W. A low-voltage activated, transient calcium current is responsible for the time-dependent depolarizing inward rectification of rat neocortical neurons in vitro. Pfluegers Arch. 410: 102-111, 1987.
24. TASKER, J. G., HOFFMAN, N. W., AND DUDEK, F. E. A comparison of three intracellular markers for combined electrophysiological, morphological and immunohistochemical analyses. J. Neurosci. Methods 38: 129-143, 1991.
25. 2+ spikes but do not generate intrinsic bursts. Soc. Neurosci. Abstr. 16: 448, 1990a.
26. TASKER, J. G., OBENAUS, A., PEACOCK, W. J., AND DUDEK, F. E. Analysis of synaptic inhibition in neocortical slices from pediatric patients with intractable epilepsy (Abstract). Epilepsia 31: 691, 1990b.
27. TASKER, J. G., PEACOCK, W. J., AND DUDEK, F. E. Local synaptic circuits and epileptiform activity in slices of neocortex from children with intractable epilepsy. J. Neurophysiol. 67: 496-507, 1992.
28. WUARIN, J. P., KIM, Y. I., CEPEDA, C., TASKER J. G., WALSH, J. P., PEACOCK, W. J., BUCHWALD, N. A., AND DUDEK, F. E. Synaptic transmission in human neocortex removed for treatment of intractable pediatric epilepsy. Ann. Neurol. 28: 503-511, 1990.