Ischaemia-reperfusion induced alterations of mitochondrial function in hypertrophied rat heart

Acta Physiologica Scandinavica

Volumn 156, Issue 1, 1996, Pages 51-60

  Leichtweis, S B ^a   Leeuwenburgh, C ^a   Chandwaney, R ^a   Parmelee, D J ^a   Ji, L L ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b Biodynamics Laboratory   (United States)

Author keywords

Glutathione; Ischaemia reperfusion; Mitochondria; Myocardium; Oxidative damage

Indexed keywords

FREE RADICAL; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SUCCINIC ACID; SUPEROXIDE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DISEASE PREDISPOSITION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE HYPERTROPHY; HYPOXEMIA; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 0029963015     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1996.427148000.x     Document Type: Article

References (40)

1. Boluyt, M.O., Opiteck, J.A., Eser, K.A. & White, T.P. 1989. Cardiac adaptations to aortic constriction in adult and aged rats. Am J Physiol 257, H643-H648.
2. Boveris, A. & Chance, B. 1973. The mitochondrial generation of hydrogen peroxide: general properties and effect of hyperbaric oxygen. Biochem J 134, 707-716.
3. Bowles, D.K., Farrar, R.P. & Starnes, J.W. 1992. Exercise training improves cardiac function after ischemia in the isolated, working rat heart. Am J Physiol 263, H804-H809.
4. Bowles, D.K. & Starnes, J.W. 1994. Exercise training improves metabolic response after ischemia in isolated working rat heart. J Appl Physiol 76, 1608-1614.
5. Chance, B., Sies, H. & Boveris, A. 1979. Hydroperoxide metabolism in mammalian organs. Physiol Rev 59, 527-605.
6. Chance, B. & Williams, G.R. 1956. The respiratory chain and oxidative phosphorylation. Adv Enzymol 17, 65-134.
7. Davies, K.J.A., Qintanilha, A.T., Brooks, G.A. & Packer, L. 1982. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Comm 107, 1198-1205.
8. Dhaliwal, H., Kirshenbaum, L.A., Randhawa, A.K. & Singal, P.K. 1991. Correlation between antioxidant changes during hypoxia and recovery on reoxygenation. Am J Physiol 261, H632-H638.
9. Dhalla, A.K. & Singal, P.K. 1994. Antioxidant changes in hypertrophied and failing guinea pig hearts. Am J Physiol 266, H1280-H1285.
10. Downey, J.M. 1990. Free radicals and their involvement during long-term myocardial ischemia and reperfusion. Annu Rev Physiol 52, 487-504.
11. Ferrari, R., Ceconin, C., Curello, S., Cargnoni, A. & Medici, D. 1986. Oxygen free radicals and reperfusion injury: the effect of ischemia and reperfusion on the cellular ability to neutralise oxygen toxicity. J Mol Cell Cardiol 18, 67-69.
12. Gaasch W.H., Zile, M.R., Hoshino, P.K., Weinberg, E.O., Rhodes, D.R. & Apstein, C.S. 1990. Tolerance of the hypertrophic heart to ischemia: studies in compensated and failing dog hearts with pressure overload hypertrophy. Circulation 81, 1644-1653.
13. Guarnieri, C., Flamigni, F. & Calderara, C.M. 1980. Role of oxygen in the cellular damage induced by reoxygenation of the hypoxic heart. J Mol Cell Cardiol 12, 797-808.
14. Gupta, M., Gameiro, A. & Singal, P.K. 1987. Reduced vulnerability of the hypertrophied rat heart to oxygen-radical injury. Can J Physiol Pharmacol 65, 1157-1164.
15. Hyslop, P.A., Hinshaw, D.B., Halsey, W.A., Schraufstätter, I.U., Sauerheber, R.D., Spragg, R.G., Jackson, J.H. & Cochrane, C.G. 1988. Mechanisms of oxidant-mediated cell injury: the glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide. J Biol Chem 263, 1665-1675.
16. Ji, L.L. & Fu, R. 1992. Responses of glutathione system and antioxidant enzymes to exhaustive exercise and hydroperoxide. J Appl Physiol 72, 549-554.
17. Ji, L.L., Fu, R.G., Mitchell, E.W., Griffiths, M., Waldrop, T.G. & Swartz, H.M. 1994. Cardiac hypertrophy alters myocardial response to ischaemia and reperfusion in vivo. Acta Physiol Scand 151, 279-290.
18. Ji, L.L., Fu, R.G., Waldrop, T.G., Lui, K. & Swartz, H.M. 1993. Myocardial response to regional ischemia and reperfusion in vivo in rat heart. Can J Physiol Pharmacol 71, 811-817.
19. Ji, L.L. & Mitchell, E.W. 1994. Effects of adriamycin on heart mitochondrial function in rested and exercised rats. Biochem Pharmacol 47, 877-885.
20. Kane, J.J., Murphy, M.L., Bissett, J.K., deSoyza, N., Doherty, J.E. & Straub, K.D. 1975. Mitochondrial function, oxygen extraction, epicardial S-T segment changes and tritiated digoxin distribution after reperfusion of ischemic myocardium. Am J Cardiol 36, 218-224.
21. Kennedy, C.H., Winston, G.W., Church, D.F. & Pryor, W. A. 1989. Benzoyl peroxide interaction with mitochondria: inhibition of respiration and induction of rapid, large-amplitude swelling. Arch Biochem Biophys 271, 455-470.
22. Kihlstrom, M. 1990. Protection effect of endurance training against reoxygenation-induced injuries in rat heart. J Appl Physiol 68, 1672-1678.
23. Kirshenbaum, L.A. & Singal, P.K. 1992. Antioxidant changes in heart hypertrophy: significance during hypoxia reoxygenation injury. Can J Physiol Pharmacol 70, 1330-1335.
24. Kuppusamy, P. & Zweier, J.L. 1989. Characterization of free radical generation by xanthine oxidase: evidence for hydroxyl radical generation. J Biol Chem 264, 9880-9884.
25. LaCagnin, L.B., Bowman, L., Ma, J.Y.C. & Miles, P.R. 1990. Metabolic changes in alveolar type II cells after exposure to hydrogen peroxide. Am J Physiol 259, L57-L65.
26. Malis, C.D. & Boventre, J.V. 1986. Mechanism of calcium potentation of oxygen free radical injury to renal mitochondria: a model for post-ischemic and toxic mitochondrial damage. J Biol Chem 261, 14201-14208.
27. -• release as a byproduct of respiration. Free Rad Res Comm 18, 127-137.
28. Park, Y., Kanekal, S. & Kehrer, J.P. 1991. Oxidative changes in hypoxic rat heart tissue. Am J Physiol 260, H1395-H1405.
29. Peng, C.F., Murphy, M.L. & Straub, K.D. 1986. Effects of early reperfusion on the mechanical and biochemical characteristics of ischemic myocardium. J Surg Res 41, 493-502.
30. Reed, D.J., Basson, J.R., Beatty, P.W., Brodie, A.E., Ellis, W.W. & Potter, D.W. 1980. High performance liquid chromatography of nanomol levels of glutathione, glutathione disulfide and related thiols and disulfides. Anal Biochem 106, 55-62.
31. Sen, C.K., Rankinen, T., Vaisanen, S. & Rauramaa. 1994. Oxidative stress after human exercise: effect of n-acetylcysteine supplementation. J Appl Physiol 76, 2570-2577.
32. Shlafer, M., Myers, C. & Adkins, S. 1987. Mitochondrial hydrogen peroxide generation and activities of glutathione peroxidase and superoxide dismutase following global ischemia. J Mol Cell Cardiol 19, 1195-1206.
33. Simpson, P.J. & Lucchesi, B.R. 1987. Free radicals and myocardial ischemia and reperfusion injury. J Lab Clin Med 110, 13-30.
34. Sordahl, L.A., McCollum, W.B., Wood, W.G. & Schwartz, A. 1973. Mitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure. Am J Physiol 224, 497-502.
35. Turrens, J.F., Beconi, M., Barilla, J., Chavez, U.B. & McCord, J.M. 1991. Mitochondrial generation of oxygen radicals during reoxygenation of ischemic tissues. Free Rad Res Comm 12-13, 681-689.
36. Uchiyama, M. & Mihara, M. 1978. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86, 271-278.
37. Van Bilsen, M., Van der Vusse, G.J., Coumans, W.A., De Graoot, M.J.M., Willemsen, P.H.M. & Reneman, R.S. 1989. Degradation of adenine nucleotides in ischemic and reperfused rat heart. Am J Physiol 257, H47-H54.
38. Weinstein, E.S., Benson, D.W., Ratcliffe, D., Maksem, J. & Fry, D.E. 1985. Experimental myocardial ischemia: differential injury of mitochondrial subpopulations. Arch Surgery 120, 332-338.
39. Weinstein, E.S., Spector, M.L., Adams, M., Yokum, M.D., Humphrey, R.W. & Fry, D.E. 1986. Mitochondrial and myocardial performance: response to ischemia and reperfusion. Arch Surgery 121, 324-329.
40. Wikman-Coffelt, J., Parmley, W.W. & Mason, D.T. 1979. The cardiac hypertrophy process: analysis of factors determining pathological vs. physiological development. Circ Res 45, 697-707.