Insulin resistance in the pathogenesis of dyslipidemia

Diabetes Care

Volumn 19, Issue 4, 1996, Pages 387-389

  Garg, Abhimanyu ^a,b,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B100; CHOLESTEROL ACYLTRANSFERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADIPOSE TISSUE; ANIMAL CELL; CONFERENCE PAPER; DIABETES MELLITUS; DYSLIPIDEMIA; FAMILIAL HYPERCHOLESTEROLEMIA; FATTY ACID METABOLISM; HORMONE ACTION; HUMAN; HUMAN TISSUE; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; INTRAVENOUS DRUG ADMINISTRATION; LIPOPROTEIN METABOLISM; NONHUMAN; RAT; RECEPTOR BINDING; SKELETAL MUSCLE;

EID: 0029962966     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.19.4.387     Document Type: Conference Paper

References (34)

1. Garg A, Helderman JH, Koffler M, Ayuso R, Rosenstock J, Raskin P: Relationship between lipoprotein levels and in vivo insulin action in normal young white men. Metabolism 37:982-987, 1988
2. Abbott WGH, Lilloja S, Young AA, Zawadzki JK, Yki-Jarvinen H, Christin L, Howard BV. Relationships between plasma lipoprotein concentrations and insulin action in an obese hyperinsulinemic population Diabetes 36:897-904, 1987
3. Laakso M, Sarlund H, Mykkanen L: Insulin resistance is associated with lipid and lipoprotein abnormalities in subjects with varying degrees of glucose tolerance. Arteriosclerosis 10:223-231, 1990
4. Karhapaa P, Malkki M, Laakso M: Isolated low HDL cholesterol, an insulin-resistance state. Diabetes 43:411-417, 1994
5. Mykkanen L, Haffner SM, Ronnemaa T, Bergman R, Leino A, Laakso M: Is there a sex difference in the association of plasma insulin level and insulin sensitivity with serum lipids and lipoproteins? Metabolism 43:523-528, 1994
6. Reaven GM, Chen YD, Jeppesen J, Maheux P, Krauss RM. Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. J Clin Invest 92 141-146, 1993
7. Selby JV, Austin MA, Newman B, Zhang D, Quesenberry CP Jr, Mayer EJ, Krauss RM LDL subclass phenotypes and the insulin resistance syndrome in women. Circulation 88:381-387, 1993
8. Steiner G, Vranic M: Hyperinsulinemia and hypertriglyceridemia, a vicious cycle with atherogenic potential. Int J Obes 6 (Suppl. 1):117-124, 1982
9. Berliner JA, Frank JL, Karasic D, Capdeville M Lipoprotein-induced insulin resistance in aortic endothelium. Diabetes 33:1039-1044, 1984
10. Rinninger F, Wolf B, Haering Hu, Bachmann W. Lack of a lipoprotein-induced insulin resistance in hepatoma cells in culture. Diabetologia 29:457-461, 1986
11. Garg A, Helderman JH, Grundy SM, Koffler M, Unger RH: Insulin resistance underlies primary hypertriglyceridemia (Abstract). Clin Res 37:449A, 1989
12. Grundy SM, Mok HY, Zech L, Steinberg D, Berman M. Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia J Clin Invest 63:1274-1283, 1979
13. Kissebah AH, Alfarsi S, Adams PW: Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man, normolipemic subjects, familial hypertriglyceridemia, and familial combined hyperlipidemia. Metabolism 30:856-868, 1981
14. Boden G: Fatty acids and insulin resistance. Diabetes Care 19:394-395, 1996
15. Eckel RH, Prasad PA, Kern PA, Marshall S: Insulin regulation of lipoprotein lipase in cultured isolated rat adipocytes. Endocrinology 114:1665-1671, 1984
16. Yki-Jarvinen H, Taskinen MR, Koivisto VA, Nikkila EA: Response of adipose tissue lipoprotein lipase activity and serum lipoproteins to acute hyperinsulinemia in man Diabetologia 27:364-369, 1984
17. Eckel RH, Yost TJ: Weight reduction increases adipose tissue lipoprotein lipase responsiveness in obese women. J Clin Invest 80:992-997, 1987
18. Farese RV Jr, Yost TJ, Eckel RH: Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans. Metabolism 40:214-216, 1991
19. Pollare T, Vessby B, Lithell H: Lipoprotein lipase activity in skeletal muscle is related to insulin sensitivity. Arterioscler Thromb 11:1192-1203, 1991
20. Ferraro RT, Eckel RH, Larson DE, Fontvielle AM, Rising R, Jensen DR, Ravussin E: Relationship between skeletal muscle lipoprotein lipase activity and 24-hour macronutrient oxidation J Clin Invest 92: 441-445, 1993
21. Baynes C, Henderson AD, Anyaoku V, Richmond W, Hughes CL, Johnston DG, Elkeles RS: The role of insulin insensitivity and hepatic lipase in the dyslipidemia of type 2 diabetes. Diabetic Med 8:560-566, 1991
22. Karhapaa P, Voutilainen E, Kovanen PT, Laakso M Insulin resistance in familial and nonfamilial hypercholesterolemia. Arterioscler Thromb 13:41-47, 1993
23. Galvan AQ, Santoro D, Natali A, Sampietro T, Boni C, Masoni A, Buzzigoli G, Ferrannini E: Insulin sensitivity in familial hypercholesterolemia. Metab Clin Exp 42: 1359-1364, 1993
24. Wade DP, Knight BL, Soutar AK: Hormonal regulation of low-density lipoprotein (LDL) receptor activity in human hepatoma HepG2 cells: insulin increases LDL receptor activity and diminishes its suppression by exogenous LDL Eur J Biochem 174:213-218, 1988
25. Schrezenmeir M, Keppler I, Fenselau S, Weber P, Biesalski HK, Probst R, Laue C, Zuchhold HD, Prellwitz W, Beyer J: The phenomenon of a high triglyceride response to an oral lipid load in healthy subjects and its link to the metabolic syndrome. Ann NY Acad Sci 683:302-314, 1993
26. Jeppesen J, Hollenbeck CB, Zhou M-Y, Coulston AM, Jones C, Chen Y-DI, Reaven GM: Relation between insulin resistance, hyperinsulinemia, postheparin plasma lipoprotein lipase activity and postprandial lipemia. Arterioscler Thromb Vasc Biol 15:320-324, 1995
27. Yang LY, Kuksis A, Steiner G: Comparison of the effect of hyperinsulinemia on acyl-CoA: cholesterol acyltransferase activity in the liver and intestine of the rat. Atherosclerosis 107:25-34, 1994
28. Abate N, Vega GL, Garg A, Grundy SM: Abnormal cholesterol distribution among lipoprotein fractions in normolipidemic patients with mild NIDDM. Atherosclerosis 118 111-122, 1995
29. Lin RC: Effects of hormones on apolipoprotein secretion in cultured rat hepatocytes. Metabolism 37:745-751, 1988
30. Elshourbagy NA, Boguski MS, Lias WS, Jefferson LS, Gordon JI, Taylor JM: Expression of rat apolipoprotein A-IV and A-1 genes: mRNA induction during development and in response to glucocorticoids and insulin. Proc Natl Acad Sci USA 82:8242-8246, 1985
31. Masumoto A, Koga S, Uchida E, Ibayashi H: Effects of insulin, dexamethasone and glucagon on the production of apolipoprotein A-I in cultured rat hepatocytes. Atherosclerosis 70:217-223, 1988
32. Brinton EA, Eisenberg S, Breslow JL: Human HDL cholesterol levels are determined by apoA-1 fractional catabolic rate, which correlates inversely with estimates of HDL particle size: effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution. Arterioscler Thromb 14:707-720, 1994
33. Dullaart RP, Sluiter WJ, Dikkeschei LD, Hoogenberg K, van Tol A. Effect of adiposity on plasma lipid transfer protein activities: a possible link between insulin resistance and high density lipoprotein metabolism Eur J Clin Invest 24:188-194, 1994
34. Arai T, Yamashita S, Hirano K-i, Sakai N, Kotani K, Fujioka S, Nozaki S, Keno Y, Yamane M, Shinohara E, Waliul Islam AHM, Ishigami M, Nakamura T, Kameda-Takamura K, Tokunaga K, Matsuzawa Y: Increased plasma cholesteryl ester transfer protein in obese subjects: a possible mechanism for reduction of serum HDL cholesterol levels in obesity. Arterioscler Thromb 14:1129-1136, 1994