Antibody binding to a peptide but not the whole protein by recognition of the C-terminal carboxy group

Archives of Biochemistry and Biophysics

Volumn 329, Issue 2, 1996, Pages 208-214

  Liang, T Chyau ^a   Luo, Weiping ^b   Hsieh, Jer Tsong ^b   Lin, Sue Hwa ^b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

antipeptide antibodies; C CAM; C terminal epitope; conformation

Indexed keywords

EPITOPE;

AMINO ACID SEQUENCE; ANTIGEN ANTIBODY REACTION; ANTIGEN RECOGNITION; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; PRIORITY JOURNAL;

EID: 0029962239     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0210     Document Type: Article

References (21)

1. Niman, H. L., Houghten, R. A., Walker, L. E., Reisfeld, R. A., and Wilson, I. A. (1983) Proc. Natl. Acad. Sci. USA 80, 4949.
2. Tanaka, T., Slamon, D. J., and Cline, M. J. (1985) Proc. Natl. Acad. Sci. USA 82, 3400-3404.
3. Bairoch, A. (1992) Nucleic Acids Res. 20, 2013-2018.
4. Chou, P. Y., and Fasman, G. D. (1978) Adv. Enz. 47, 45-147.
5. Gamier, J., Osguthorpe, D. J., and Robson, B. (1978) J. Mol. Biol. 120, 97-120.
6. Barany, G., and Merrifield, R. B. (1979) in The Peptides (Gross, E., and Meienhofer, J. Eds.), Vol. 2A, pp. 1-284, Academic Press, New York.
7. Wang, W., and Liang, T. C. (1994) Biochem. Biophys. Res. Commun. 201, 835-840.
8. Culic, O., Huang, Q. H., Flanagan, D., Hixson, D., and Lin, S. H. (1992) Biochem. J. 285, 47-53.
9. Lin, S. H., Culic, O., Flanagan, D., and Hixson, D. C. (1991) Biochem. J. 278, 155-161.
10. Jameson, B. A., and Wolf, H. (1988) CABIOS 4(1), 181-186.
11. Cheung, P. H., Earley, K., Liang, T. C., and Lin, S. H. (1993) Arch. Biochem. Biophys. 305, 563-569.
12. Thompson, N. L., Panzica, M. A., Hull, G., Lin, S. H., Curran, T. R., Gruppuso, P. A., Baum, O., Reutter, W., and Hixson, D. C. (1993) Cell Growth Differ. 4, 257-268.
13. Dyson, H. J., Lerner, R. A., and Wright, P. E. (1988) Annu. Rev. Biophys. Biophys. Chem. 17, 305-324.
14. Hopp, T. P., and Woods, K. R. (1981) Proc. Natl. Acad. Sci. USA 78, 3824-3828.
15. Thornton, J. M., Edwards, M. S., Taylor, W. R., and Barlow, D. J. (1986) EMBO J. 5, 409-413.
16. Novotny, J., Handschumacher, M., Haber, E., Bruccoleri, R. E., Carlson, W. B., Fanning, D. W., Smith, J. A., and Rose, G. D. (1986) Proc. Natl. Acad. Sci. USA 83, 226-230.
17. Rothbard, J. B., and Taylor, W. R. (1988) EMBO J. 7, 93-100.
18. Wilson, I. A., Niman, H. L., Houghton, R. A., Cherenson, A. R., Connolly, M. L., and Lerner, R. A. (1984) Cell 37, 767-778.
19. Perutz, M. (1992) Protein Structure: New Approaches to Disease and Therapy, pp. 277-295, Freeman, New York, NY.
20. Moroder, L., Papini, A., Siglmuller, G., Kocher, K., Dorrer, E., and Schneider, C. H. (1992) Biol. Chem. Hoppe-Seyler 373, 315-321.
21. Field, J., Nikawa, J. I., Broek, D., MacDonald, B., Rodgers, L., Wilson, I. A., Lerner, R. A., and Wigler, M. (1988) Mol. Cell. Biol. 8, 8568-8572.