Detection of empty HLA class II molecules on cord blood B cells

Blood

Volumn 87, Issue 9, 1996, Pages 3970-3976

  Garban, Frédéric ^b   Ericson, Mats ^b   Roucard, Corinne ^b   Rabian Herzog, Claire ^b   Teisserenc, Hélène ^b   Sauvanet, Eric ^b   Charron, Dominique ^b   Mooney, Nuala ^a  

^a INSERM   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD23 ANTIGEN; DODECYL SULFATE SODIUM; HLA ANTIGEN CLASS 2; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ADULT; ANTIGEN DETECTION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FETUS; FETUS CELL; HUMAN; HUMAN CELL; MIXED LYMPHOCYTE REACTION; PRIORITY JOURNAL; SPLEEN CELL; UMBILICAL CORD BLOOD;

EID: 0029961128     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.9.3970.bloodjournal8793970     Document Type: Article

References (36)

1. Splawsky JB, Jelinek DF, Lipsky PE: Delineation of the functional capacity of human neonatal lymphocytes. J Clin Invest 87:545, 1991
2. Tucci A, Mouzaki A, James H, Bonnefoy JY, Zubler RH: Are cord blood B cells functionally mature? Clin Exp Immunol 84:389, 1991
3. Mooney NA, Grillot-Courvalin C, Hivroz C, Ju LY, Charron D: Early biochemical events after MHC class II mediated signaling on human B lymphocytes. J Immunol 145:2070, 1990
4. Kvist S, Wiman K, Claesson L, Peterson PA, Dobberstein B: Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens. Cell 29:61, 1982
5. Lamb CA, Cresswell P: Assembly and transport properties of invariant chain trimers and HLA-DR invariant chain complexes. J Immunol 148:3478, 1992
6. Roche PA, Cresswell P: Invariant chain association with HLA DR molecules inhibits immunogenic peptide binding. Nature 345:615, 1990
7. Amigorena S, Drake JR, Webster P, Mellman I: Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes. Nature 369:113, 1994
8. Qiu Y, Xu X, Wandinger-Ness A, Dalke DP, Pierce SK: Separation of subcellular compartments containing distinct functional forms of MHC class II. J Cell Biol 125:595, 1994
9. Cresswell P: Assembly, transport and function of MHC class II molecules. Annu Rev Immunol 12:259, 1994
10. Sadegh-Nasseri S, Germain RN: A role for peptide in determining MHC class II structure. Nature 35:167, 1991
11. Germain RN, Rinker AG: Peptide binding inhibits protein aggregation of invariant free class II dimers and promotes surface expression of occupied molecules. Nature 363:725, 1993
12. Medley ML, Urban RG, Strominger JL: Assembly and peptide binding of major histocompatibility complex class II heterodimers in an in vitro translation system. Proc Natl Acad Sci USA 91:10479, 1994
13. Neefjes JJ, Ploegh HL: Inhibition of proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistant αβ heterodimers in endosomes. EMBO J 11:411, 1992
14. Stern LJ, Wiley DC: The human class II MHC protein HLA DR-1 assembles as empty αβ heterodimers in the absence of antigenic peptide. Cell 68:465, 1992
15. Schafer P, Pierce S: Evidence for dimers of MHC molecules in B lymphocytes and their role in low affinity T cell response. Immunity 1:699, 1994
16. Ericson M, Sundstrom M, Sansom DM, Charron DJ: Mutually exclusive binding of peptide and invariant chain to major histocompatibility class II antigens. J Biol Chem 269:26531, 1994
17. + T cell recognition of class II molecules. J Immunol 154:5153, 1995
18. Charron DJ, MacDevitt HO: Analysis of HLA-D region associated molecules with monoclonal antibody. Proc Natl Acad Sci USA 76:6567, 1979
19. Carrel S, Tosi R, Gross N, Tanigaki R, Carmagnola AL, Accola RS: Subset of human Ia like molecules defined by monoclonal antibodies. Mol Immunol 18:403, 1981
20. Rubinstein D, Roska AK, Lipsky PE: Liver sinusoïdal lining cells express class II major histocompatibility antigens but are poor stimulators of fresh allogeneic T lymphocytes. J Immunol 137:1803, 1986
21. Fermand JP, Schmitt C, Brouet C: Distribution of class II DQ antigens normal and leukemic lymphoïd cells. Eur J Immunol 15:1183, 1985
22. Epstein AL, Marder RJ, Winter JN, Fox RI: Two new monoclonal antibodies (LN1 LN2) reactive in B5 formalin fixed parffin embedded tissues with follicular and mantle zone human lymphocytes and derived tumors. J Immunol 133:1028, 1984
23. Koch N, Moldenhauer G, Hofmann WJ, Moller P: Rapid intracellular pathway gives rise to cell surface expression of the MHC class II associated invariant chain (CD74). J Immunol 147:2643, 1991
24. Roche PA, Teletski CL, Stang E, Bakke O, Long EO: Cell surface HLA DR-Invariant chain complexes are targeted to endosomes by rapid internalization. Proc Natl Acad Sci USA 90:8581, 1993
25. Fu X, Karr RW: HLA-DRa chain residues located on the outer loops are involved in non-polymorphic and polymorphic antibody binding epitopes. Hum Immunol 39:253, 1994
26. Lanzavecchia A, Reid PA, Watts C: Irreversible association of peptides with class II MHC molecules in living cells. Nature 357:249, 1992
27. Benaroch P, Yilla M, Raposo G, Ito K, Miwa K, Geuze HJ, Ploegh HL: How MHC class II molecules reach the endocytic pathway. EMBO J 14:37, 1995
28. Nelson CA, Petzol SJ, Unanue ER: Identification of two distinct properties of class II major histocompatibility complex associated peptides. Proc Natl Acad Sci USA 90:1227, 1993
29. Dezin LK, Cresswell P: HLA DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82:155, 1995
30. + T cell function in mice lacking the p41 isoform of invariant chain. Immunity 3:385, 1995
31. Hayakawa K, Tarlinton D, Hardy R: Absence of MHC class II expression distinguishes fetal from adult B lymphopoiesis in mice. J Immunol 152:4801, 1994
32. Tulp A, Verwoed D, Dobberstein B, Ploegh HL, Pieters J: Isolation of the intracellular MHC class II compartment. Nature 369:120, 1994
33. Ceman S, Rudersdorf RA, Petersen JM, DeMars R: DMA and DMB are the only genes in the class II region oh the human MHC needed for class II associated antigen processing. J Immunol 154:2545, 1995
34. Arimilli S, Cardoso C, Mukku P, Baichwal V, Nag B: Refolding and reconstitution of functionally active complexes of human leukocyte antigen DR2 and myelin basic protein peptide from recombinant α and β polypeptide chains. J Biol Chem 270:971, 1995
35. Wagner JE, Kernan NA, Broxmeyer HE, Gluckman E: Allogeneic umbilical cord blood transplantation report of results in 26 patients. Blood 10:86, 1993 suppl 1
36. Thompson C: Umbilical cords: Turning garbage into clinical gold. Science 268:805, 1995