Dietary supplement of neosugar alters the fecal flora and decreases activities of some reductive enzymes in human subjects

American Journal of Clinical Nutrition

Volumn 63, Issue 5, 1996, Pages 709-716

  Buddington, Randal K ^a   Williams, Carol H ^b   Chen, Sui Chi ^b   Witherly, Steven A ^b  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b NONE

Author keywords

bifidobacteria; fecal flora; Fructooligosaccharide; humans; microflora; reductive enzymes

Indexed keywords

BETA GLUCURONIDASE; FRUCTOSE OLIGOSACCHARIDE; NITROREDUCTASE; OXYGENASE;

ADULT; AEROBIC BACTERIUM; ANAEROBIC BACTERIUM; ARTICLE; DIET SUPPLEMENTATION; DIETARY INTAKE; ENTEROBACTERIACEAE; ENZYME ACTIVITY; FECES ANALYSIS; FECES MICROFLORA; FEMALE; FOOD COMPOSITION; HUMAN; HUMAN EXPERIMENT; LACTOBACILLUS BIFIDUS; MALE; NORMAL HUMAN;

EID: 0029960158     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/63.5.709     Document Type: Article

References (21)

1. Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Rev Infect Dis 1990;12:S252-61.
2. Chadwick RW, George S, Claxton LD. Role of the gastrointestinal mucosa and microflora in the bioactivation of dietary and environmental mutagens or carcinogens. Drug Metab Rev 1992;24:425-92.
3. Perman JA. Gastrointestinal flora: developmental aspects and effects of nutrients. In: Lebenthal E, ed. Human gastrointestinal development. New York: Raven Press, 1989:777-86.
4. Rowland IR. Factors affecting metabolic activity of the intestinal microflora. Drug Metab Rev 1988;19:243-61.
5. Roland N, Nugon-Baudon L, Rabot S. Interactions between the intestinal flora and xenobiotic metabolizing enzymes and their health consequences. In: Simopoulos AP, Coring T, Rerat A, eds. Intestinal flora, immunity, nutrition and health. World Rev Nutr Diet 1993;74: 123-48.
6. Dwyer J. Dietary fiber and colorectal cancer risk. Nutr Rev 1993;51: 147-55.
7. Williams CH, Witherly SA, Buddington RK Influence of dietary neosugar on selected bacterial groups of the human faecal microbiota Microbial Ecol Health Dis 1994;7:91-7.
8. Gibson GR, Beatty EB, Wang X, Cummings JH. Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology 1995;108:975-82.
9. Mitsuoka T, Hidaka H, Eida T Effect of fructooligosaccharides on intestinal microflora. Die Nahrung 1987;31:427-36.
10. G-β-D-galactosylsucrose) on fecal flora and fecal putrefactive products of cats. J Vet Med Sci 1993;55:291-5.
11. Rowland IR, Tanaka R. The effects of transgalactosylated oligosaccharide on gut flora metabolism in rats associated with a human fecal microflora. J Appl Bacteriol 1993;74:667-74.
12. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 1995;125: 1401-12.
13. Summanen P, Baron EJ, Citron DM, Strong C, Wexler HM, Finegold SM, eds. Wadsworth anaerobic bacteriology manual. 5th ed. Belmont, CA: Star Publishing, 1993.
14. Wang X, Gibson GR. Effect of the in vitro fermentation of oligofructose and inulin by bacteria growing in the human large intestine. J Appl Bacteriol 1993;75:373-80.
15. Ling WH, Korpela R, Mykkaneen H, Salminen S, Hanninen O. Lactobacillus strain GG supplementation decreases colonic hydrolytic and reductive enzyme activities in healthy female adults. J Nutr 1994;124: 18-23.
16. Pedrosa MC, Golner BB, Goldin BR, Dallal GB, Russell RM. Survival of yogurt-containing organisms and Lactobacillus gasseri (ADH) and their effect on bacterial enzyme activity in the gastrointestinal tract of health and hypochlorhydric elderly subjects. Am J Clin Nutr 1995;61: 353-9.
17. McConnell MA, Tannock GW. A note on lactobacilli and β-glucuronidase activity in the intestinal contents of mice. J Appl Bacteriol 1993;74:649-51.
18. Kulkarni N, Reddy BS. Inhibitory effect of Bifidobacterium longum cultures on the azoxymethane-induced aberrant crypt foci formation and fecal bacterial β-glucuronidase. Proc Soc Exp Biol Med 1994; 207:278-83.
19. Zhang XB, Ohta Y. Microorganisms in the gastrointestinal tract of the rat prevent absorption of the mutagen-carcinogen 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole. Can J Microbiol 1993;39:841-5.
20. Gibson GR, Wang X. Inhibitory effects of bifidobacteria on other colonic bacteria. J Appl Bacteriol 1994;77:412-20.
21. Ueda K. Immunity provided by colonized enteric bacteria Bifido Microflora 1986;5:67-72.