Direct synthesis of 3,4-dihydro-2H-pyrido[1,2-a]pyrimidines, by addition reactions with 2-aminopyridines

Tetrahedron Letters

Volumn 37, Issue 15, 1996, Pages 2615-2618

  Mellor, John M ^a   Merriman, Glynn D ^a   Rataj, Helen ^a   Reid, Gillian ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIDINE DERIVATIVE; PYRIDO[1,2 A]PYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0029960097     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00341-3     Document Type: Article

References (10)

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3. Gregoire, P. J.; Mellor, J. M.; Merriman, G. D., Tetrahedron, 1995, 51, 6133.
4. Mellor, J. M.; Merriman, G. D.; Mitchell, P. L., Tetrahedron, 1995, 51, 12383.
5. Mellor, J. M.; Merriman, G. D., Tetrahedron, 1995, 51, 6115.
6. +)
7. 3. In δH (270MHz) for (4) 5.08 (1H, d J 6.0, CH-N)
8. Hermecz, I.; Meszaros, Z., Adv. Heterocyclic Chem., 1983, 33, 241.
9. Houlihan, W. J.; Cheon, S. H.; Parrino, V. A.; Handley, D. A.; Larson, D. A., J. Med. Chem., 1993, 36, 3098; Houlihan, W. J.; Munder, P. G.; Handley, D. A.; Cheon, S. H; Parrino, V. A., J. Med. Chem., 1995, 38, 234.
10. Houlihan, W. J.; Cheon, S. H.; Parrino, V. A.; Handley, D. A.; Larson, D. A., J. Med. Chem., 1993, 36, 3098; Houlihan, W. J.; Munder, P. G.; Handley, D. A.; Cheon, S. H; Parrino, V. A., J. Med. Chem., 1995, 38, 234.