Multiple requirements for nematode spliced leader RNP function in trans- splicing

RNA

Volumn 2, Issue 8, 1996, Pages 746-755

  Denker, John A ^a   Maroney, Patricia A ^a   Yu, Yi Tao ^a   Andrew Kanost, R ^a   Nilsen, Timothy W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

nematode; Sm RNP; spliced leader; trans splicing; U5 snRNA

Indexed keywords

NUCLEOTIDE; RIBONUCLEOPROTEIN; SIGNAL PEPTIDE; SMALL NUCLEAR RNA;

ARTICLE; BINDING SITE; EXON; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; RNA SEQUENCE; RNA SPLICING; SEQUENCE ANALYSIS; SPLICEOSOME;

ANIMALS; ASCARIS; BASE SEQUENCE; BINDING SITES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; OXYGEN; RIBONUCLEOPROTEINS; RNA SPLICING; RNA, HELMINTH; RNA, MESSENGER;

EID: 0029959519     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Aebi M, Hornig H, Weissmann C. 1987. 5′ cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region not by the conserved 5′ GU. Cell 50:237-248.
2. Bruzik JP, Maniatis T. 1992. Spliced leader RNAs from lower eukaryotes are trans-spliced in mammalian cells. Nature 360:692-695.
3. Bruzik JP, Maniatis T. 1995. Enhancer-dependent interaction between 5′ and 3′ splice sites in trans. Proc Natl Acad Sci USA 92:7056-7059.
4. Bruzik JP, Steitz JA. 1990. Spliced leader RNA sequences can substitute for the essential 5′ end of U1 RNA during splicing in a mammalian in vitro system. Cell 62:889-899.
5. Bruzik JP, van Doren K, Hirsh D, Steitz JA. 1988. Trans-splicing in-volves a novel form of small ribonucleoprotein particles. Nature 335:559-562.
6. Chiara MD, Reed R. 1995. A two-step mechanism for 5′ and 3′ splice-site pairing. Nature 375:510-513.
7. Cortes JJ, Sontheimer EJ, Seiwert SD, Steitz JA. 1993. Mutations in the conserved loop of human U5 snRNA generate the use of novel cryptic 5′ splice sites in vivo. EMBO J 12:5191-5200.