Neuroprotective effects of RPR 104632, a novel antagonist at the glycine site of the NMDA receptor, in vitro

European Journal of Pharmacology

Volumn 300, Issue 3, 1996, Pages 237-246

  Boireau, Alain ^a   Malgouris, Christiane ^a   Burgevin, Marie Claude ^a   Pény, Colette ^a   Durand, Gabrielle ^a   Bordier, Françoise ^a   Meunier, Mireille ^a   Miquet, Jean Marie ^a   Daniel, Marc ^a   Chevet, Thierry ^a   Jimonet, Patrick ^a   Mignani, Serge ^a   Blanchard, Jean Charles ^a   Doble, Adam ^a  

^a SANOFI   (France)

Author keywords

glutamate; glycine receptor antagonist; neurotoxicity; NMDA receptor channel complex; RPR 104632

Indexed keywords

1 (3 BROMOBENZYL) 6,8 DICHLORO 3,4 DIHYDRO 2H 1,2,4 BENZOTHIADIAZINE 1,1 DIOXIDE 3 CARBOXYLIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; 3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 5,7 DICHLORO 1,2,3,4 TETRAHYDRO 4 (3 PHENYLUREIDO) 2 QUINOLINECARBOXYLIC ACID; 5,7 DICHLOROKYNURENIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; 7 CHLOROKYNURENIC ACID; BENZOTHIADIAZINE DERIVATIVE; CYCLIC GMP; DIZOCILPINE; GLYCINE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RADIOLIGAND; RPR 104632; TENOCYCLIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BINDING SITE; BRAIN CORTEX; BRAIN SLICE; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HISTOLOGY; ISOMER; MALE; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; STEREOSPECIFICITY;

EID: 0029959010     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00780-6     Document Type: Article

References (22)

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