A nonpeptidal peptidomimetic agonist of the insect FLRFamide myosuppressin family

Peptides

Volumn 17, Issue 2, 1996, Pages 313-320

  Nachman, Ronald J ^a   Olender, Eric H ^b   Roberts, Victoria A ^b   Holman, G Mark ^a   Yamamoto, Daisuke ^c  

^a U S DEPARTMENT OF AGRICULTURE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

Author keywords

Arachidonic acid; Binding; Cockroach; FMRFamide; Ligand; Lipoxygenase; Locust; Molecular dynamics; Myoinhibition; NDGA; Neuromuscular junction; Peptidomimetic

Indexed keywords

4 BROMOPHENACYL BROMIDE; BENZETHONIUM CHLORIDE; INDOMETACIN; NORDIHYDROGUAIARETIC ACID;

ANIMAL TISSUE; ARTICLE; COCKROACH; CONTROLLED STUDY; GASTROINTESTINAL MOTILITY; NEUROMUSCULAR SYNAPSE; NONHUMAN; PEST CONTROL; PRIORITY JOURNAL; TENEBRIO MOLITOR;

AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; BENZETHONIUM; COCKROACHES; INDOMETHACIN; INSECT HORMONES; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; NEUROMUSCULAR JUNCTION; NEUROPEPTIDES; NORDIHYDROGUAIARETIC ACID; OLIGOPEPTIDES; PROTEIN CONFORMATION;

EID: 0029958913     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0196-9781(95)02097-7     Document Type: Article

References (30)

1. Cook, B. J.; Wagner, R. M. Comparative effects of leucomyosuppressin on the visceral muscle systems of the cockroach Leucophaea maderae. Comp. Biochem, Physiol. [C] 99:95-99; 1991.
2. Evans, B. E.; Bock, M. G.; Rittle, K. E.; et al. Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc. Natl. Acad. Sci. USA 83:4918-4922; 1986.
3. Fonagy, A.; Schoofs, L.; Proost, P.; Van Damme, J.; Bueds, H.; DeLoof, A. Isolation, primary structure and synthesis of neomyosuppressin, a myoinhibiting neuropeptide from the grey fleshfly, Neobelleria bullata. Comp. Biochem. Physiol. [C] 102:239-245; 1992.
4. Goetz, M. A.; Lopez, M.; Monaghen, R. L.; Chang, R. S. L.; Lotti, V.; Chen, T. B. Asperlicin, a novel nonpeptidal cholecystokinin antagonist from Aspergillus alliaceus. J. Antibiot. 38:1633-1637; 1985.
5. Holman, G. M.; Cook, B. J.; Nachman, R. J. Isolation, primary structure and synthesis of leucomyosuppressin, an insect neuropeptide that inhibits spontaneous contractions of the cockroach hindgut. Comp. Biochem. Physiol. [C] 85:329-333; 1986.
6. Holman, G. M.; Nachman, R. J.; Schoofs, L.; Hayes, T. K.; Wright, M. S.; DeLoof, A. The Leucophaea maderae hindgut preparation: A rapid and sensitive bioassay tool for the isolation of insect myotropins of other insect species. Insect Biochem. 21:107-112; 1991.
7. Holman, G. M.; Nachman, R. J.; Wright, M. S. Insect neuropeptides. Annu. Rev. Entomol. 35:201; 1990.
8. Keeley, L. L.; Hayes, T. K. Speculations on biotechnology applications for insect neuroendocrine research. Insect Biochem. 17:639-651; 1987.
9. Kingan, T. G.; Teplow, D. B.; Phillips, J. M.; et al. A new peptide in the FMRFamide family isolated from the CNS of the hawkmoth, Manduca sexta. Peptides 11:849-856; 1990.
10. Lange, A. B.; Orchard, I.; Wang, Z.; Nachman, R. J. A nonpeptide agonist of the invertebrate receptor for SchistoFLRFarnide (PDV-DHVFLRFamide), a member of a subfamily of insect FMRFamide-related peptides. Proc. Natl. Acad. Sci. USA 92:9250-9253; 1995.
11. Nachman, R. J.; Coast, G. M.; Roberts, V. A.; Holman, G. M. Incorporation of chemical/conformational components into mimetic analogs of insect neuropeptides. In: Konopinski, D.; Sobotka, W., eds. Insects: Chemical, physiological and environmental aspects. Wroclaw: Wroclaw University Press; (in press).
12. Nachman, R. J.; Holman, G. M.; Haddon, W. F. Leads for insect neuropeptide mimetic development. Arch. Insect Biochem. Physiol. 22:181-197; 1993.
13. Nachman, R. J.; Holman, G. M.; Hayes, T. K.; Beier, R. C. Structure-activity relationships for inhibitory insect myosuppressins: Contrast with the stimulatory sulfakinins. Peptides 14:665-670; 1993.
14. Nachman, R. J.; Tilley, J. W.; Hayes, T. K.; Holman, G. M.; Beier, R. C. Pseudopeptide mimetic analogs of insect neuropeptides. In: Hedin, P. A.; Menn, J. J.; Hollingworth, R. M., eds. Natural and engineered pest management agents. Washington, DC: American Chemical Society; 1994:210-229.
15. Nachman, R. J.; Yamamoto, D.; Holman, D. M.; Beier, R. C. Pseudopeptides and a nonpeptide that mimic the biological activity of the myosuppressin insect neuropeptide family. In: Loeb, M. J.; Kelly, T. J., eds. Insect neurochemistry and neurophysiology. Boca Raton: CRC Press; 1993:321. (Correction: p. 321, line 16; 60 nM)
16. Nichols, R. Isolation and structural characterization of Drosophila TDVDHVFLRFamide and FMRFamide-containing neural peptide. J. Mol. Neurosci. 3:213-218; 1992.
17. Peeff, N.; Orchard, I.; Lange, A. B. The effects of FMRFamide-related peptides on an insect (Locusta migratoria) visceral muscle. J. Insect Physiol. 39:207-213; 1993.
18. Peeff, N.; Orchard, I.; Lange, A. B. Isolation, sequence and bioactivity of PDVDHVFLRFamide and ADVGHVFLRFamide peptide from the locust central nervous systems. Peptides 15:387-392; 1994.
19. Piomelli, D.; Volterra, A.; Dale, N.; et al. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature 328:38-43; 1987.
20. Robb, S.; Packman, L. C.; Evans, P. D. Isolation, primary structure and bioactivity of SchistoFLRF-amide, a FMRF-amide-like neuropeptide for the locust, Schistocerca gregaria. Biochem. Biophys. Res. Commun. 160:850-856; 1989.
21. Schoofs, L.; Holman, G. M.; Nachman, R. J.; Hayes, T. K.; DeLoof, A. Structure, function, and distribution of insect myotropic peptides. In: Davey, K. G.; Peter, R. E.; Tobe, S. S., eds. Perspectives in comparative endocrinology, Ottawa: National Council of Canada; 1994:155-165.
22. Schoofs, L.; Holman, M.; Paemen, L.; Veelaert, D.; Amelinck, M.; DeLoof, A. Isolation, identification, and synthesis of PDVDHVFLRFamide (SchistoFLRFamide) in Locusta migratoria and its association with the male accessory glands, the salivary glands, the heart and the oviduct. Peptides 14:409-421; 1993.
23. Snider, R. M.; Constatine, J. W.; Lowe, J. A., III; et al. A potent nonpeptide antagonist of the substance P (Nki) receptor. Science 251:435-436; 1991.
24. Struthers, R. S.; Rivier, J.; Hagler, A. T. Molecular dynamics and minimum energy conformations of GnRH and analogs; A methodology for computer-aided drug design. Ann. NY Acad. Sci. 439:81-96; 1985.
25. Wang, Z.; Orchard, I.; Lange, A. B. Identification and characterization of two receptors for SchistoFLRFamide on locust oviduct. Peptides 15:875-882; 1994.
26. Wang, Z.; Orchard, I.; Lange, A. B.; Chen, S. Binding and activation regions of the decapeptide PDVDHVFLRFamide (Schisto-FLRFamide). Neuropeptides (in press).
27. Yamamoto, D. Activation of protein kinase C promotes glutamate-mediated transmission at the neuromuscular junction of the mealworm. J. Physiol. 400:691-700; 1988.
28. Yamamoto, D.; Ishikawa, S.; Holman, G. M.; Nachman, R. J. Leucomyosuppressin, a novel insect neuropeptide, inhibits evoked transmitter release at the mealworm neuromuscular junction. Neurosci. Lett. 95:137-142; 1988.
29. Yamamoto, D.; Washio, H. Curare has a voltage-dependent blocking action on the glutamate synapse. Nature 281:372-373; 1979.
30. Yamamura, Y.; Ogawa, H.; Chihara, T.; et al. OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist. Science 252:572-574; 1991.