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Volumn 142, Issue 3, 1996, Pages 707-715

Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies

Author keywords

Bacillus anthracis; Epitope mapping; Protective antigen

Indexed keywords

ASPARAGINE; ASPARTIC ACID; BACTERIAL ANTIGEN; BACTERIAL TOXIN; CELL RECEPTOR; EPITOPE; IODINE 125; ISOLEUCINE; MONOCLONAL ANTIBODY; PHENYLALANINE; SERINE;

EID: 0029958827     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/13500872-142-3-707     Document Type: Article
Times cited : (110)

References (31)
  • 1
    • 0000363324 scopus 로고
    • Rapid lethal effect in rats of a third component found upon fractionating the toxin of Bacillus anthracis
    • Beall, F. A., Taylor, M. J. & Thorne, C. B. (1962). Rapid lethal effect in rats of a third component found upon fractionating the toxin of Bacillus anthracis. J Bacteriol 83, 1274-1280.
    • (1962) J Bacteriol , vol.83 , pp. 1274-1280
    • Beall, F.A.1    Taylor, M.J.2    Thorne, C.B.3
  • 2
    • 0024327681 scopus 로고
    • Calcium is required for the expression of anthrax lethal toxin activity in the macrophage-like cell line J774A.1
    • Bhatnagar, R., Singh, Y., Leppla, S. H. & Friedlander, A. M. (1989). Calcium is required for the expression of anthrax lethal toxin activity in the macrophage-like cell line J774A.1. Infect Immun 57, 2107-2114.
    • (1989) Infect Immun , vol.57 , pp. 2107-2114
    • Bhatnagar, R.1    Singh, Y.2    Leppla, S.H.3    Friedlander, A.M.4
  • 3
    • 0022454535 scopus 로고
    • A comparison of ELISA screening methods for the production of monoclonal antibodies against soluble protein antigens
    • Brennand, D.M., Danson, M. J. & Hough, D.W. (1986). A comparison of ELISA screening methods for the production of monoclonal antibodies against soluble protein antigens. J Immunol Methods 93, 9-14.
    • (1986) J Immunol Methods , vol.93 , pp. 9-14
    • Brennand, D.M.1    Danson, M.J.2    Hough, D.W.3
  • 4
    • 0022372691 scopus 로고
    • Fusion of mouse-mouse cells to produce hybridoma secreting monoclonal antibody
    • Earley, E. M. & Osterling, M. C. (1985). Fusion of mouse-mouse cells to produce hybridoma secreting monoclonal antibody. J Tissue Cult Methods 9, 141-146.
    • (1985) J Tissue Cult Methods , vol.9 , pp. 141-146
    • Earley, E.M.1    Osterling, M.C.2
  • 5
    • 0026044658 scopus 로고
    • Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells
    • Escuyer, V. & Collier, R. J. (1991). Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells. Infect Immun 59, 3381-3386.
    • (1991) Infect Immun , vol.59 , pp. 3381-3386
    • Escuyer, V.1    Collier, R.J.2
  • 6
    • 0021285324 scopus 로고
    • Immunoelectrophoretic analysis, roxicity, and kinetics of in vitro production of the protective antigen and lethal factor components of Bacillus anthracis toxin
    • Ezzell, J. W., Ivins, B. E. & Leppla, S. H. (1984). Immunoelectrophoretic analysis, roxicity, and kinetics of in vitro production of the protective antigen and lethal factor components of Bacillus anthracis toxin. Infect Immun 45, 761-767.
    • (1984) Infect Immun , vol.45 , pp. 761-767
    • Ezzell, J.W.1    Ivins, B.E.2    Leppla, S.H.3
  • 7
    • 0014263069 scopus 로고
    • Purification and properties of in vitro-produced anthrax toxin components
    • Fish, D. C., Mahlandt, B. G., Dobbs, J. P. & Lincoln, R. E. (1968). Purification and properties of in vitro-produced anthrax toxin components. J Bacteriol 95, 907-918.
    • (1968) J Bacteriol , vol.95 , pp. 907-918
    • Fish, D.C.1    Mahlandt, B.G.2    Dobbs, J.P.3    Lincoln, R.E.4
  • 8
    • 0022891493 scopus 로고
    • Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process
    • Friedlander, A. M. (1986). Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem 261, 7123-7126.
    • (1986) J Biol Chem , vol.261 , pp. 7123-7126
    • Friedlander, A.M.1
  • 9
    • 0023932170 scopus 로고
    • Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin
    • Gordon, V. M., Leppla, S. H. & Hewlett, E. L. (1988). Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect Immun 56, 1066-1069.
    • (1988) Infect Immun , vol.56 , pp. 1066-1069
    • Gordon, V.M.1    Leppla, S.H.2    Hewlett, E.L.3
  • 10
    • 0021287698 scopus 로고
    • Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines
    • Green, L. M., Reade, J. L. & Ware, C. F. (1984). Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines. J Immunol Methods 70, 257-268.
    • (1984) J Immunol Methods , vol.70 , pp. 257-268
    • Green, L.M.1    Reade, J.L.2    Ware, C.F.3
  • 11
    • 0022521851 scopus 로고
    • Use of monoclonal antibodies to detect conformational alterations in lactate dehydrogenase isoenzyme 5 on heat denaturation and on adsorption to polystyrene plates
    • Hollander, Z. & Katchalski-Katzir, E. (1986). Use of monoclonal antibodies to detect conformational alterations in lactate dehydrogenase isoenzyme 5 on heat denaturation and on adsorption to polystyrene plates. Mol Immunol 23, 927-933.
    • (1986) Mol Immunol , vol.23 , pp. 927-933
    • Hollander, Z.1    Katchalski-Katzir, E.2
  • 12
    • 0028088404 scopus 로고
    • Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
    • Kumpel, K. R., Arora, N. & Leppla, S. H. (1994). Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol Microbiol 13, 1093-1100.
    • (1994) Mol Microbiol , vol.13 , pp. 1093-1100
    • Kumpel, K.R.1    Arora, N.2    Leppla, S.H.3
  • 14
    • 0000947082 scopus 로고
    • Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
    • Leppla, S. H. (1982). Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells Proc Natl Acad Sci USA 79, 3162-3166.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 3162-3166
    • Leppla, S.H.1
  • 15
    • 0024214705 scopus 로고
    • Production and purification of anthrax toxin
    • Leppla, S. H (1988). Production and purification of anthrax toxin. Methods Enzymol 165, 103-116.
    • (1988) Methods Enzymol , vol.165 , pp. 103-116
    • Leppla, S.H.1
  • 16
    • 0002661972 scopus 로고
    • The anthrax toxin complex
    • Edited by J. E. Alouf & J. H. Freer. New York: Academic Press
    • Leppla, S. H. (1991). The anthrax toxin complex. In Sourcebook of Bacterial Protein Toxins, pp. 277-302. Edited by J. E. Alouf & J. H. Freer. New York: Academic Press.
    • (1991) Sourcebook of Bacterial Protein Toxins , pp. 277-302
    • Leppla, S.H.1
  • 17
    • 0001825875 scopus 로고
    • Proteolytic activation of anthrax toxin bound to cellular receptors
    • Edited by F. Fehrenbach, J. E. Alouf, P. Falmagne, W. Goebel, J. Jeljaszewicz, D. Jurgens &. R. Rappuoli. Stuttgart: Gustav Fischer
    • Leppla, S. H., Friedlander, A. M. & Cora, E. M. (1987). Proteolytic activation of anthrax toxin bound to cellular receptors. In Bacterial Protein Toxins, pp. 111-112. Edited by F. Fehrenbach, J. E. Alouf, P. Falmagne, W. Goebel, J. Jeljaszewicz, D. Jurgens &. R. Rappuoli. Stuttgart: Gustav Fischer.
    • (1987) Bacterial Protein Toxins , pp. 111-112
    • Leppla, S.H.1    Friedlander, A.M.2    Cora, E.M.3
  • 19
    • 0025720455 scopus 로고
    • Location of receptor-binding region of protective antigen from Bacillus anthracis
    • Little, S. F. & Lowe, J. R. (1991). Location of receptor-binding region of protective antigen from Bacillus anthracis. Biochem Biophys Res Commun 180, 531-537.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 531-537
    • Little, S.F.1    Lowe, J.R.2
  • 20
    • 0023895994 scopus 로고
    • Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin
    • Little, S. F., Leppla, S. H. & Cora, E. (1988). Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin. Infect Immun 56, 1807-1813.
    • (1988) Infect Immun , vol.56 , pp. 1807-1813
    • Little, S.F.1    Leppla, S.H.2    Cora, E.3
  • 21
    • 0025290784 scopus 로고
    • Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin
    • Little, S. F., Leppla, S. H. & Friedlander, A. M. (1990). Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin. Infect Immun 58, 1606-1013.
    • (1990) Infect Immun , vol.58 , pp. 1606-11013
    • Little, S.F.1    Leppla, S.H.2    Friedlander, A.M.3
  • 22
    • 0028018856 scopus 로고
    • Anthrax protective antigen forms oligomers during intoxication of mammalian cells
    • Milne, J. C., Furlong, D. Hanna, P. C., Wall, J. S. & Collier, R. J. (1994). Anthrax protective antigen forms oligomers during intoxication of mammalian cells. J Biol Chem 269, 20607-20612.
    • (1994) J Biol Chem , vol.269 , pp. 20607-20612
    • Milne, J.C.1    Furlong, D.2    Hanna, P.C.3    Wall, J.S.4    Collier, R.J.5
  • 23
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 24
    • 0026794750 scopus 로고
    • Functional characterization of protease-treated Bacillus anthracis protective antigen
    • Novak, J. M., Stein, M.-P., Little, S. F., Leppla, S. H. & Friedlander, A. M. (1992). Functional characterization of protease-treated Bacillus anthracis protective antigen. J Biol Chem 267, 17186-17193.
    • (1992) J Biol Chem , vol.267 , pp. 17186-17193
    • Novak, J.M.1    Stein, M.-P.2    Little, S.F.3    Leppla, S.H.4    Friedlander, A.M.5
  • 25
    • 0024837128 scopus 로고
    • A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in viro
    • Singh, Y., Chaudhary, V. K. & Leppla, S. H. (1989). A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in viro. J Biol Chem 264, 19103-19107.
    • (1989) J Biol Chem , vol.264 , pp. 19103-19107
    • Singh, Y.1    Chaudhary, V.K.2    Leppla, S.H.3
  • 26
    • 0025858389 scopus 로고
    • The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity
    • Singh, Y., Klimpel, K. R., Quinn, C. P., Chaudhary, V. K. & Leppla, S. H. (1991). The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity. J Biol Chem 266, 15493-15497.
    • (1991) J Biol Chem , vol.266 , pp. 15493-15497
    • Singh, Y.1    Klimpel, K.R.2    Quinn, C.P.3    Chaudhary, V.K.4    Leppla, S.H.5
  • 27
  • 28
    • 73049164375 scopus 로고
    • Purification of factor I and recognition of a third factor of the anthrax toxin
    • Stanley, J. L. & Smith, H. (1961). Purification of factor I and recognition of a third factor of the anthrax toxin. J Gen Microbiol 26, 49-60.
    • (1961) J Gen Microbiol , vol.26 , pp. 49-60
    • Stanley, J.L.1    Smith, H.2
  • 29
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Prof Natl Acad Sci USA 76, 4350-4354.
    • (1979) Prof Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 30
    • 0023758535 scopus 로고
    • Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis
    • Welkos, S. L., Lowe, J. R., Eden-McCutchan, F., Vodkin, M., Leppla, S. H. & Schmidt, J. J. (1988). Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene 69, 287-300.
    • (1988) Gene , vol.69 , pp. 287-300
    • Welkos, S.L.1    Lowe, J.R.2    Eden-McCutchan, F.3    Vodkin, M.4    Leppla, S.H.5    Schmidt, J.J.6
  • 31
    • 0026338822 scopus 로고
    • Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases
    • Wu, X. C., Lee, W., Tran, L. & Wong, S. L. (1991). Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases. J Bacteriol 173, 4952-4958.
    • (1991) J Bacteriol , vol.173 , pp. 4952-4958
    • Wu, X.C.1    Lee, W.2    Tran, L.3    Wong, S.L.4


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