Cloning and chromosomal mapping of the mouse DNA dependent protein kinase gene

Immunogenetics

Volumn 45, Issue 1, 1996, Pages 1-5

  Hamatani, Kiyohiro ^a   Matsuda, Yoichi ^b   Araki, Ryoko ^a   Itoh, Masahiro ^a   Abe, Masumi ^c  

^a RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN RECEPTOR; PROTEIN KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CENTROMERE; CHROMOSOME 16; CHROMOSOME 8Q; CHROMOSOME MAP; COMBINED IMMUNODEFICIENCY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME LOCALIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCUS; GENETIC RECOMBINATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; RECEPTOR GENE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HUMANS; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES;

ANIMALIA;

EID: 0029958752     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050159     Document Type: Article

References (27)

1. Anderson, C. W., Lees-Miller, S. P. The nuclear serine/threonine protein kinase DNA-PK. Crit Rev Eukaryot Gene Exp 2: 283-314, 1992
2. Banga, S. S., Hall, K. T., Sandhu, A. K., Weaver, D. T., and Athwal, R. S. Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8. Mutat Res 315: 239-247, 1994
3. Benton, W. D. and Davis, R. W. Screening λgt recombinant clones by hybridization to single plaques in situ. Science 196: 180-182, 1977
4. Biedermann, K. A., Sun, J., Giaccia, A. J., Tosto, L. M., and Brown, J. M. scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc Natl Acad Sci USA 88: 1394-1397, 1991
5. Blackwell, T. K., Malynn, B. A., Pollack, R. R., Ferrier, P., Covey, L. R., Fulop, G. M., Phillips, R. A., Yancopoulos, G. D., and Alt, F. W. Isolation of scid preB cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joints. EMBO J 8: 735-742, 1989
6. Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, G. C. M., Demengeot, J., Gottlieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A., and Jackson, S. P. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80: 813-823, 1995
7. Bosma, G. C., Custer, R. P., and Bosma, M. J. A severe combined immunodeficiency mutation in the mouse. Nature 301: 527-530, 1983
8. Bosma, G. C., Davisson, M. T., Ruetsch, N. R., Sweet, H. O. Shultz, L. D., and Bosma, M. J. The mouse mutation severe combined immune deficiency (scid) is on chromosome 16. Immunogenetics 29: 54-57, 1989
9. Fulop, G. M. and Phillips, R. A. The scid mutation in mice causes a general defect in DNA repair. Nature 347: 479-482, 1990
10. Hartley, K. O., Gell, D., Smith, G. C. M., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W., and Jackson, S. P. DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82: 849-856, 1995
11. Hendrikson, E. A., Schatz, D. G., and Weaver, D. T. The scid gene encodes a transacting factor that mediates the rejoining event of Ig gene rearrangement. Genes Dev 2: 817-829, 1988
12. Hendrickson, E. A., Xiao-Qiang Qin, Bump, E. A., Schatz, D. G., Oettinger, M., and Weaver, D. T. A link between double-strand break-related repair and V(D)J recombination: The scid mutation. Proc Natl Acad Sci USA 88: 4061-4065, 1991
13. Hunter, T. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell 83: 1-4, 1995
14. Itoh, M., Hamatani, K., Komatsu, K., Araki, R., Takayama, K., and Abe, M. Human chromosome 8 (p12 → q22) complements radiosensitivity in the severe combine immune deficiency (SCID) mouse. Radiat Res 134: 364-368, 1993
15. Kirchgessner, C. U., Patil, C. K., Evans, J. W., Cuomo, C. A., Fried, L. M., Carter, T, Oettinger, M. A., Brown, J. M. DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 267: 1178-1183, 1995
16. Kim, M. G., Schuler, W., Bosma, M. J., and Marcu, K. B. Abnormal recombination of Igh D and J segments in transformed pre-B cells of scid mice. J Immunol 141: 1341-1347, 1988
17. Lieber, M. R., Hesse, J. E., Lewis, S., Bosma, G. C., Rosenberg, N., Mizuuchi, K., Bosma, M. J., and Gellert, M. The defect in murine severe combined immune deficiency joining of signal sequences but not coding segments in V(D)J recombination activity. Cell 55: 7-16, 1988
18. Malynn, B. A., Blackwell, T. K., Fulop, G. M., Rathbun, O. A., Furley, A. J. W., Ferrier, P., Heinke, L. B., Phillips, R. A., Yancopoulos, G. D., and Alt, F. W. The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism. Cell 54: 453-460, 1988
19. Matsuda, Y., Harada, Y. N., Natsuume-Sakai, S., Lee, K., Shiomi, T., and Chapman, V. M. Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding. Cytogenet Cell Genet 61: 282-285, 1992
20. Matsuda, Y. and Chapman, V. M. Application of fluorescence in situ hybridization in mouse genome analysis of the mouse. Electrophoresis 16: 261-272, 1995
21. Matsuda, Y, Hamatani, K., Itoh, M., Takahashi, E., Araki, R., and Abe, M. Localization of the importin-β gene to mouse chromosome IID and rat chromosome 10 q32.1. Genomics 36: 213-215, 1996
22. Miller, R. D., Hogg, J., Ozaki, J. H., Gell, D., Jackson, S. P., and Riblet, R. Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus. Proc Natl Acad Sci USA 92: 10792-10795, 1995
23. Okazaki, K., Nishikawa, S. I., and Sakano, H. Aberrant immunoglobulin gene rearrangement in scid mouse bone marrow cells. J Immunol 141: 1348-1352, 1988
24. Poltoratsky, V. P., Shi, X., York, J. D., Lieber, M. R., and Carter, T. H. Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases. J Immunol 155: 4529-4533, 1995
25. Schuler, W., Weiler, I. J., Schuler, A., Phillips, R. A., Rosenberg, N., Mak, T. W., Kearney, J. F., Perry, R. P., and Bosma, M. Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell 46: 963-972, 1986
26. Sipley, J. D., Menninger, J. C., Hartley, K. O., Ward, D. C., Jackson, S. P., and Anderson, C. W. Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8. Proc Natl Acad Sci USA 92: 7515-7519, 1995
27. Tonegawa, S. Somatic generation of antibody diversity. Nature 302: 575-581, 1983