Bioactivation of S-(2,2-dihalo-1,1-difluoroethyl)-L-cysteines and S- (trihalovinyl)-L-cysteines by cysteine S-conjugate β-lyase: Indications for formation of both thionoacylating species and thiiranes as reactive intermediates

Chemical Research in Toxicology

Volumn 9, Issue 7, 1996, Pages 1092-1102

  Commandeur, Jan N M ^a   King, Laurence J ^a,b   Koymans, Luc ^a   Vermeulen, Nico P E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 PHENYLENEDIAMINE; COPPER ION; CYSTEINE CONJUGATE; CYSTEINE CONJUGATE BETA LYASE; HALOOLEFIN; PYRIDOXAL;

ANIMAL CELL; ARTICLE; COVALENT BOND; ENTHALPY; GAS CHROMATOGRAPHY; KIDNEY CELL; MASS SPECTROMETRY; NEPHROTOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT;

ACYLATION; ANIMALS; BIOTRANSFORMATION; CARBON-SULFUR LYASES; CYSTEINE; HYDROCARBONS, FLUORINATED; LYASES; MALE; RATS; RATS, WISTAR; SULFHYDRYL COMPOUNDS;

ANIMALIA;

EID: 0029958578     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960049b     Document Type: Article

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