Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 13, 1996, Pages 6659-6664

  Dobie, Kenneth W ^a,b   Lee, Muriel ^c   Fantes, Judith A ^c   Graham, Elizabeth ^c   Clark, A John ^b   Springbett, Anthea ^b   Lathe, Richard ^a   McClenaghan, Margaret ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

lactoglobulin; epigenetic silencing; position effect variegation

Indexed keywords

BETA LACTOGLOBULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMOSOMAL LOCALIZATION; GENE LOCUS; GENE REARRANGEMENT; GENE STRUCTURE; MAMMARY GLAND; MILK; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; TRANSGENE;

ANIMALS; CENTROMERE; FEMALE; GENE EXPRESSION; GENE REARRANGEMENT; IN SITU HYBRIDIZATION, FLUORESCENCE; LACTOGLOBULINS; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MILK; MOSAICISM; TRANSGENES;

EID: 0029957720     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.13.6659     Document Type: Article

References (47)

1. Papiz, M. Z., Sawyer, L., Eliopoulos, E. E., North, A. C. T., Findlay, J. B. C., Sivaprasadarao, R., Jones, T. A., Newcomer, M. E. & Kraulis, P. J. (1986) Nature (London) 324, 383-385.
2. Simons, J. P., McClenaghan, M. & Clark, A. J. (1987) Nature (London) 328, 530-532.
3. Clark, A. J., Simons, J. P., Wilmut, I. & Lathe, R. (1987) Trends Biotechnol. 5, 20-24.
4. Archibald, A. L., McClenaghan, M., Hornsey, V., Simons, J. P. & Clark, A. J. (1990) Proc. Natl. Acad. Sci. USA 87, 5178-5182.
5. Wright, G., Carver, A., Cottom, D., Reeves, D., Scott, A., Simons, J. P., Wilmut, I. & Colman, A. (1991) Bio/Technology 9, 830-834.
6. Palmiter, R. D., Wilkie, T. M., Chen, H. Y. & Brinster, R. L. (1984) Cell 36, 869-877.
7. Al-Shawi, R., Burke, J., Jones, C. T., Simons, J. P. & Bishop, J. O. (1988) Mol. Cell. Biol. 8, 4821-4828.
8. Wilkie, T. M., Braun, R. E., Ehrman, E. J., Palmiter, R. D. & Hammer, R. E. (1991) Genes Dev. 5, 38-48.
9. Sandgren, E. P., Palmiter, R. D., Heckel, J. L., Daugherty, C. C., Brinster, R. L. & Degen, J. L. (1991) Cell 66, 245-256.
10. Tan, S. S., Williams, E. A. & Tam, P. P. L. (1993) Nat. Genet. 3, 170-174.
11. Butner, K. & Lo, C. W. (1986) Mol. Cell. Biol. 6, 4440-4449.
12. Talarico, D., Peverali, A. F., Gimelli, E., Meneveri, R., Mondello, C. & Valle, G. D. (1988) Mol. Cell. Biol. 8, 1336-1344.
13. McGowan, R., Campbell, R., Peterson, A. & Sapienza, C. (1989) Genes Dev. 3, 1669-1676.
14. Allen, N. D., Norris, M. L. & Surani, M. A. (1990) Cell 61, 853-861.
15. Engler, P., Haasch, D., Pinkert, C. A., Doglio, L., Glymour, M., Brinster, R. & Storb, U. (1991) Cell 65, 939-947.
16. Sweetser, D. A., Hauft, S. M., Hoppe, P. C., Birkenmeier, E. H. & Gordon, J. I. (1988) Proc. Natl Acad. Sci. USA 85, 9611-9615.
17. Bradl, M., Larue, L. & Mintz, B. (1991) Proc. Natl. Acad. Sci. USA 88, 6447-6451.
18. Mintz, B. & Bradl, M. (1991) Proc. Natl. Acad. Sci. USA 88, 9643-9647.
19. Porter, S.D. & Meyer, C.J. (1994) Development (Cambridge, U.K.) 120, 2103-2111.
20. Cattanach, B. M. (1974) Genet. Res. 23, 291-306.
21. Whitelaw, C. B. A., Archibald, A. L., Harris, S., McClenaghan, M., Simons, J. P. & Clark, A. J. (1991) Transgenic Res. 1, 3-13.
22. McClenaghan, M., Springbett, A., Wallace, R. M., Wilde, C. J. & Clark, A. J. (1995) Biochem. J. 310, 637-641.
23. Gaye, P., Hue-Delahaie, D., Mercier, J. C., Soulier, S., Vilotte, J. L. & Furet, J. P. (1986) Biochimie (Paris) 68, 1097-1107.
24. Gupta, P., Rosen, J. M., D'Eustachio, P. & Ruddle, F. H. (1982) J. Cell Biol. 93, 199-204.
25. Melton, D. A., Krieg, P. A., Rebagliati, M. R., Maniatis, T., Zinn, K. & Green, M. R. (1984) Nucleic Acids Res. 12, 7035-7056.
26. Monaghan, A. P., Davidson, D. R., Sime, C., Graham, E., Baldock, R., Bhattacharya, S. S. & Hill, R. E. (1991) Development (Cambridge, U.K.) 112, 1053-1061.
27. Klever, M., Grond-Ginsbach, C., Scherthan, H. & SchroederKurth, T. M. (1991) Hum. Genet. 86, 484-486.
28. Langer-Safer, P. R., Levine, M. & Ward, D. C. (1982) Proc. Natl. Acad. Sci. USA 79, 4381-4385.
29. Fantes, J. A., Bickmore, W. A., Fletcher, J. M., Ballesta, F., Hanson, I. M. & Heyningen, V. (1992) Am. J. Hum. Genet. 51, 1286-1294.
30. Pietras, D. F., Bennett, K. L., Siracusa, L. D., Woodworth-Gutai, M., Chapman, V. M., Gross, K. W., Kane-Haas, C. & Hastie, N. D. (1983) Nucleic Acids Res. 11, 6965-6983.
31. Fantes, J. A., Oghene, K., Boyle, S., Danes, S., Fletcher, J.M., et al. (1995) Genomics 25, 447-461.
32. Whitelaw, C. B. A., Harris, S., McClenaghan, M., Simons, J. P. & Clark, A. J. (1992) Biochem. J. 286, 31-39.
33. Spofford, J. B. (1976) in Genetics and Biology of Drosophila, eds. Ashburner, M. & Novitski, E. (Academic, London), Vol. 1c, pp. 955-1019.
34. Dorer, D. R. & Henikoff, S. (1994) Cell 77, 993-1002.
35. Singer, M. J., Marcotte, B. A. & Selker, E. U. (1995) Mol. Cell. Biol. 15, 5586-5597.
36. Matzke, M. & Matzke, A. J. M. (1993) Annu. Rev. Plant. Physiol. Plant Mol. Biol. 44, 53-76.
37. Molenaar, A. J., Davis, S. R. & Wilkins, R. J. (1992) J. Histochem. Cytochem. 40, 611-618.
38. Robinson, G. W., McKnight, R. A., Smith, G. H. & Hennighausen, L. (1995) Development (Cambridge, U.K.) 121, 2079-2090.
39. Robertson, G., Garrick, D., Wu, W., Kearns, M., Martin, D. & Whitelaw, E. (1995) Proc. Natl. Acad. Sci. USA 92, 5371-5375.
40. Mintz, B. (1970) Symp. Int. Soc. Cell Biol. 9, 15-42.
41. Hartmann-Goldstein, I. J. (1967) Genet. Res. 10, 143-159.
42. Manuelidis, L. (1991) Proc. Natl. Acad. Sci. USA 88, 1049-1053.
43. Mehtali, M., LeMeur, M. & Lathe, R. (1990) Gene 91, 179-184.
44. Culver, K. W., Ram, Z., Wallbridge, S., Ishii, H., Oldfield, E.H. & Blaese, R. M. (1992) Science 256, 1550-1552.
45. Wallace, H., McLaren, K., Al-Shawi, R. & Bishop, J. O. (1994) J. Endocrinol. 143, 107-120.
46. Cozzi, E. & White, D. J. G. (1995) Nat. Med. 1, 964-966.
47. Gimelli, G., Varone, P., Pezzolo, A., Lerone, M. & Pistoia, V. (1993) J. Med. Genet. 30, 429-432.