Synthesis and binding affinities of a series of 1,2-benzisoxazole-3-carboxamides to dopamine and serotonin receptors

European Journal of Medicinal Chemistry

Volumn 31, Issue 12, 1996, Pages 957-964

  Nuhrich, A ^a   Varache Lembege M ^a   Vercauteren, J ^a   Dokhan, R ^b   Renard, P ^c   Devaux, G ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b LDK France   (France)

^c ADIR   (France)

Author keywords

1,2 benzisoxazole 3 carboxamide; 5 HT3 receptor; 5 HT4 receptor; Dopamine D2 receptor

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 1,2 BENZISOXAZOLE 3 CARBOXAMIDE DERIVATIVE; BENZAMIDE DERIVATIVE; DOPAMINE RECEPTOR; GRANISETRON; RACLOPRIDE; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT; TROPISETRON; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONFORMATION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; RECEPTOR AFFINITY; STEREOCHEMISTRY;

EID: 0029957641     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(97)86174-0     Document Type: Article

References (34)

1. 1 Andrews PLR, Bhandari P (1993) Eur J Cancer 29 A. S11-S16
2. 2 Borsini F, Templeton D, Turconi M, Nicola M, Schiantarelli P, Donetti A (1990) Psychopharmacology 101, S7
3. 3 Clarke DE (1992) Front Headache Res 2, 118-128
4. 4 Buchheit KH, Buhl T (1991) Eur J Pharmacol 205, 203-208
5. 5 Boddeke HWG, Kalkman HO (1990) Br J Pharmacol 101, 281-284
6. 6 Gaster LM, Sanger GJ (1994) Drugs Future 19, 1109-1121
7. 7 Bockaert J, Sebben M, Dumuis A (1990) Mol Pharmacol 37, 408-411
8. 8 Dumuis A, Sebben M, Bockaert J (1989) Naunuyn-Schmiedeberg's Arch Pharmacol 340, 403-410
9. 9 Harrington RA, Hamilton CW, Brogden RN, Linkewich JA, Romankiewicz JA, Heel RC (1983) Drugs 25, 451-494
10. 10 Wadworth AN, Heel RC (1990) Drugs 40, 863-879
11. 11 Vollinga RC, Menge WMPB, Leurs R, Timmerman H (1995) J Med Chem 38, 266-271
12. 12 Ganellin CR, Hosseini SK, Khalaf YS et al (1995) J Med Chem 38, 3342-3350
13. 13 Van Wijngaarden I, Hamminga D, Van Hes R et al (1993) J Med Chem 36, 3693-3699
14. 14 Anzini M, Cappelli A, Vomero S et al (1995) J Med Chem 38, 2692-2704
15. 15 Langlois M, Yang D, Brémont B, Shen S (1995) Med Chem Lett 5, 795-798
16. 16 Yang D, Brémont B, Shen S, Keti S, Langlois M (1996) Eur J Med Chem 31, 231-239
17. 17 Bermudez J, Fake CS, Joiner GF et al (1990) J Med Chem 33, 1924-1929
18. 18 Borsche W (1909) Ber 42, 1310-1318
19. 19 Furniss BS, Hannaford AJ, Smith PWG, Tatchell AR (1989) In: Vogel's Textbook of Practical Organic Chemistry (5th ed), Longman Scientific & Technical, Harlow, 413
20. 20 Clinton RO, Laskowski SC (1953) US Pat 2,626,260; Chem Abstr (1954) 48, 732 f
21. 20 Clinton RO, Laskowski SC (1953) US Pat 2,626,260; Chem Abstr (1954) 48, 732 f
22. 21 Archer S, Lewis TR, Unser MJ (1957) J Am Chem Soc 79, 4194-4198
23. 22 Aue WP, Bartholdi E, Ernst RR (1976) J Chem Phys 64, 2229-2246
24. 23 Bax A, Subramanian S (1986) J Magn Reson 67, 565-569
25. 24 Bax A, Summers MF (1986) J Am Chem Soc 108, 2093-2094
26. 25 Cabezas N, Martinez M, Galvez E, Arias MS, Florencio F, Garcia-Blanco S (1988) J Mol Struct 172, 381-394
27. 26 Cabezas N, Martinez M, Galvez E, Arias MS, Florencio F, Sanz-Aparicio J (1989) J Mol Struct 197, 59-72
28. 27 Galvez E, Arias MS, Cabezas N, Martinez M (1990) J Mol Struct 220, 55-61
29. 28 Turconi M, Nicola M, Quintero MG et al (1990) J Med Chem 33, 2101-2108
30. 29 Kato S, Morie T, Yoshida N, Matsumoto J (1992) Chem Pharm Bull 40, 1470-1475
31. 30 Langlois M, Soulier JL, Yang D et al (1993) Eur J Med Chem 28, 869-880
32. 31 Peroutka SJ, Snyder SH (1979) Mol Pharmacol 16, 687-699
33. 32 Peroutka SJ, Snyder SH (1979) Mol Pharmacol 16, 700-708
34. 33 Cheng Y, Prusoff WH (1973) Biochem Pharmacol 22, 3099-3108