-
1
-
-
0022357068
-
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
-
M. Burke, C. Thompson, J. Elcombe, T. Halpert, T. Haaparanta, and R. Mayer: Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem. Pharmacol. 34, 3337-3345 (1985).
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 3337-3345
-
-
Burke, M.1
Thompson, C.2
Elcombe, J.3
Halpert, T.4
Haaparanta, T.5
Mayer, R.6
-
2
-
-
0022350885
-
Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
-
R. Lubet, R. Mayer, J. Cameron, R. Nims, M. D. Burke, T. Wolff, and F. Guengerich: Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 238, 43-48 (1985).
-
(1985)
Arch. Biochem. Biophys.
, vol.238
, pp. 43-48
-
-
Lubet, R.1
Mayer, R.2
Cameron, J.3
Nims, R.4
Burke, M.D.5
Wolff, T.6
Guengerich, F.7
-
3
-
-
0027179679
-
Methoxyresorufin and benzyloxyresorufin - Substrates preferentially metabolized by cytochrome-P4501A2 and cytochrome-2B, respectively, in the rat and mouse
-
P. V. Nerurkar, S. S. Park, P. E. Thomas, R. W. Nims, and R. A. Lubet: Methoxyresorufin and benzyloxyresorufin - substrates preferentially metabolized by cytochrome-P4501A2 and cytochrome-2B, respectively, in the rat and mouse. Biochem. Pharmacol. 46, 933-943 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 933-943
-
-
Nerurkar, P.V.1
Park, S.S.2
Thomas, P.E.3
Nims, R.W.4
Lubet, R.A.5
-
4
-
-
0027364928
-
Specificity of substrate and inhibitor probes for human cytochromes-P450 1A1 and 1A2
-
W. Tassaneeyakul, D. J. Birkett, M. E. Verronese, M. E. McManus, R. H. Tukey, L. C. Quattrochi, H. V. Gelboin, and J. D. Miners: Specificity of substrate and inhibitor probes for human cytochromes-P450 1A1 and 1A2. J. Pharmacol Exp. Ther. 265, 401-407 (1993).
-
(1993)
J. Pharmacol Exp. Ther.
, vol.265
, pp. 401-407
-
-
Tassaneeyakul, W.1
Birkett, D.J.2
Verronese, M.E.3
McManus, M.E.4
Tukey, R.H.5
Quattrochi, L.C.6
Gelboin, H.V.7
Miners, J.D.8
-
5
-
-
0028241592
-
Caffeine metabolism by human hepatic cytochromes P450 - Contributions of 1A2, 2E1, and 3A isoforms
-
W. Tassaneeyakul, D. J. Birkett, M. E. McManus, W. Tassaneeyakul, M. E. Veronese, T. Anderson, R. S. Tukey, and J. O. Miners: Caffeine metabolism by human hepatic cytochromes P450 - contributions of 1A2, 2E1, and 3A isoforms. Biochem. Pharmacol. 47, 1767-1776 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1767-1776
-
-
Tassaneeyakul, W.1
Birkett, D.J.2
McManus, M.E.3
Tassaneeyakul, W.4
Veronese, M.E.5
Anderson, T.6
Tukey, R.S.7
Miners, J.O.8
-
6
-
-
0027432032
-
Cytochrome-P450 induction and metabolism of alkoxyresorufins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle
-
G. A. E. van't Klooster, B. J. Blaauboer, J. Noordhoek, and A. S. J-. P. A. M. van Miert: Cytochrome-P450 induction and metabolism of alkoxyresorufins, ethylmorphine and testosterone in cultured hepatocytes from goats, sheep and cattle. Biochem. Pharmacol. 46, 1781-1790 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1781-1790
-
-
Van't Klooster, G.A.E.1
Blaauboer, B.J.2
Noordhoek, J.3
Van Miert, A.S.J.-P.A.M.4
-
7
-
-
0023720480
-
Caffeine intake, fasting caffeine and caffeine clearance in patients with liver diseases
-
G. Marchesini, G. A. Checchia, G. Grossi, R. Lolli, G. P. Bianchi, M. Zoli, and E. Pisi: Caffeine intake, fasting caffeine and caffeine clearance in patients with liver diseases. Liver 8, 241-246 (1988).
-
(1988)
Liver
, vol.8
, pp. 241-246
-
-
Marchesini, G.1
Checchia, G.A.2
Grossi, G.3
Lolli, R.4
Bianchi, G.P.5
Zoli, M.6
Pisi, E.7
-
8
-
-
0026646696
-
Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes
-
F. Berthou, B. Guillois, C. Riche, Y. Dreano, E. Jacqz-Aigrain, and P. H. Beaune: Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes. Xenobiotica 19, 671-680 (1992).
-
(1992)
Xenobiotica
, vol.19
, pp. 671-680
-
-
Berthou, F.1
Guillois, B.2
Riche, C.3
Dreano, Y.4
Jacqz-Aigrain, E.5
Beaune, P.H.6
-
9
-
-
0026906604
-
Caffeine as a probe for human cytochromes P450: Validation using cDNA-expression immunoinhibition and microsomal kinetic and inhibitor techniques
-
W. Tassaneeyakul, Z. Mohamed, D. J. Birkett, M. E. McManus, M. E. Veronese, R. S. Tukey, L. C. Quattrochi, F. J. Gonzalez, and J. O. Miners: Caffeine as a probe for human cytochromes P450: validation using cDNA-expression immunoinhibition and microsomal kinetic and inhibitor techniques. Pharmacogenetics 2, 173-183 (1992).
-
(1992)
Pharmacogenetics
, vol.2
, pp. 173-183
-
-
Tassaneeyakul, W.1
Mohamed, Z.2
Birkett, D.J.3
McManus, M.E.4
Veronese, M.E.5
Tukey, R.S.6
Quattrochi, L.C.7
Gonzalez, F.J.8
Miners, J.O.9
-
10
-
-
0021590772
-
Interspecies comparisons of in vivo caffeine pharmacokinetics in man, monkey, rabbit, rat and mouse
-
M. Bonati, R. Latini, G. Tognoni, J. F. Young, and S. Garattini: Interspecies comparisons of in vivo caffeine pharmacokinetics in man, monkey, rabbit, rat and mouse. Drug Metab. Rev. 15, 1355-1383 (1985).
-
(1985)
Drug Metab. Rev.
, vol.15
, pp. 1355-1383
-
-
Bonati, M.1
Latini, R.2
Tognoni, G.3
Young, J.F.4
Garattini, S.5
-
11
-
-
0028336745
-
Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva
-
U. Fuhr and K. L. Rost: Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. Pharmacogenetics 4, 109-116 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 109-116
-
-
Fuhr, U.1
Rost, K.L.2
-
12
-
-
0024343858
-
PA (P-4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
-
PA (P-4501A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proc. Natl. Acad. Sci. U.S.A. 86, 7696-7700 (1989).
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 7696-7700
-
-
Butler, M.A.1
Iwasaki, M.2
Guengerich, F.P.3
Kadlubar, F.F.4
-
13
-
-
0028278064
-
Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults
-
C. Cazeneuve, G. Pons, E. Rey, J. M. Treluyer, T. Cresteil, G. Thiroux, P. Dathis, and G. Olive: Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults. Br. J. Clin. Pharmacol. 37, 405-412 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.37
, pp. 405-412
-
-
Cazeneuve, C.1
Pons, G.2
Rey, E.3
Treluyer, J.M.4
Cresteil, T.5
Thiroux, G.6
Dathis, P.7
Olive, G.8
-
14
-
-
0022544144
-
Analogues of caffeine and theophylline: Effects of structural alterations on affinity at adenosine receptors
-
J. W. Daly, W. L. Padgett, and M. T. Shamim: Analogues of caffeine and theophylline: effects of structural alterations on affinity at adenosine receptors. J. Med. Chem. 29, 1305-1308 (1986).
-
(1986)
J. Med. Chem.
, vol.29
, pp. 1305-1308
-
-
Daly, J.W.1
Padgett, W.L.2
Shamim, M.T.3
-
15
-
-
0020264370
-
Liquid chromatographic determination of caffeine in biological fluids
-
D. B. Haughey, R. Greenberg, S. F. Schaal, and J. L. Lima: Liquid chromatographic determination of caffeine in biological fluids. J. Chromatogr. 229, 387-395 (1982).
-
(1982)
J. Chromatogr.
, vol.229
, pp. 387-395
-
-
Haughey, D.B.1
Greenberg, R.2
Schaal, S.F.3
Lima, J.L.4
-
16
-
-
0018091195
-
Application of Akaike's information criteria (AIC) in the evaluation of linear pharmacokinetic equations
-
K. Yamaoka, T. Nakagawa, and T. Uno: Application of Akaike's information criteria (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm. 6, 165-175 (1978).
-
(1978)
J. Pharmacokinet. Biopharm.
, vol.6
, pp. 165-175
-
-
Yamaoka, K.1
Nakagawa, T.2
Uno, T.3
-
18
-
-
0028213982
-
Applicability of cultured hepatocytes derived from goat, sheep and cattle in comparative drug metabolism studies
-
G. A. E. van't Klooster, F. M. A. Woutersenvannijanten, B. J. Blaauboer, J. Noordhoek, and A. S. J. P. A. M. van Miert: Applicability of cultured hepatocytes derived from goat, sheep and cattle in comparative drug metabolism studies. Xenobiotica 24, 417-428 (1994).
-
(1994)
Xenobiotica
, vol.24
, pp. 417-428
-
-
Van't Klooster, G.A.E.1
Woutersenvannijanten, F.M.A.2
Blaauboer, B.J.3
Noordhoek, J.4
Van Miert, A.S.J.P.A.M.5
-
19
-
-
0027992976
-
The use of in vitro methods for studying drug metabolism to replace animal studies as part of veterinary product license applications
-
I. C. Shaw: The use of in vitro methods for studying drug metabolism to replace animal studies as part of veterinary product license applications. Toxicol. In Vitro 8, 917-919 (1994).
-
(1994)
Toxicol. in Vitro
, vol.8
, pp. 917-919
-
-
Shaw, I.C.1
-
20
-
-
0028203387
-
Antipyrine and caffeine dispositions in clinically normal dogs and dogs with progressive liver diseases
-
D. M. Boothe, J. M. Cullen, J. A. Calvin, W. L. Jenkins, S. A. Brown, R. A. Green, and D. E. Corner: Antipyrine and caffeine dispositions in clinically normal dogs and dogs with progressive liver diseases. Am. J. Vet. Res. 55, 254-261 (1994).
-
(1994)
Am. J. Vet. Res.
, vol.55
, pp. 254-261
-
-
Boothe, D.M.1
Cullen, J.M.2
Calvin, J.A.3
Jenkins, W.L.4
Brown, S.A.5
Green, R.A.6
Corner, D.E.7
-
21
-
-
0019854562
-
Effect of caffeine on circulating theophylline levels in beagle dogs
-
F. L. S. Tse, K. H. Valia, T. W. Szeto, T. J. Raimondo, and B. Koplowitz: Effect of caffeine on circulating theophylline levels in beagle dogs. J. Pharm. Sci. 70, 395-399 (1981).
-
(1981)
J. Pharm. Sci.
, vol.70
, pp. 395-399
-
-
Tse, F.L.S.1
Valia, K.H.2
Szeto, T.W.3
Raimondo, T.J.4
Koplowitz, B.5
-
22
-
-
0020693706
-
Pharmacology, pharmacokinetics and behavioral effects of caffeine in horses
-
E. W. Greene, W. E. Woods, and T. Tobin: Pharmacology, pharmacokinetics and behavioral effects of caffeine in horses. Am. J. Vet. Res. 44, 57-63 (1983).
-
(1983)
Am. J. Vet. Res.
, vol.44
, pp. 57-63
-
-
Greene, E.W.1
Woods, W.E.2
Tobin, T.3
-
23
-
-
0029031411
-
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys
-
P. Bullock, R. Pearce, A. Draper, J. Podval, W. Bracken, J. Veltman, P. Thomas, and A. Parkinson: Induction of liver microsomal cytochrome P450 in cynomolgus monkeys. Drug Metab. Dispos. 23, 736-748 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 736-748
-
-
Bullock, P.1
Pearce, R.2
Draper, A.3
Podval, J.4
Bracken, W.5
Veltman, J.6
Thomas, P.7
Parkinson, A.8
-
24
-
-
0021882609
-
The fate of chronically consumed caffeine in the monkey (Macacca fasicularis)
-
S. Gilbert, B. Stavric, R. Klassen, and D. Rice: The fate of chronically consumed caffeine in the monkey (Macacca fasicularis). Fundam. Appl. Toxicol. 5, 578-587 (1985).
-
(1985)
Fundam. Appl. Toxicol.
, vol.5
, pp. 578-587
-
-
Gilbert, S.1
Stavric, B.2
Klassen, R.3
Rice, D.4
-
25
-
-
0022263133
-
Purification and characterization of human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation: Two prototypes for genetic polymorphism in oxidative drug metabolism
-
L. M. Distlerath, P. E. B. Reilly, M. V. Martin, G. G. Davis, G. R. Wilkinson, and F. P. Guengerich: Purification and characterization of human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation: two prototypes for genetic polymorphism in oxidative drug metabolism. J. Biol. Chem. 260, 9057-9067 (1985).
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 9057-9067
-
-
Distlerath, L.M.1
Reilly, P.E.B.2
Martin, M.V.3
Davis, G.G.4
Wilkinson, G.R.5
Guengerich, F.P.6
-
26
-
-
0027295760
-
Identification of P450 enzymes involved in metabolism of verapamil in humans
-
H. K. Kroemer, J. C. Gautire, P. Beaune, C. Henderson, C. R. Wolf, and M. Eichelbaum: Identification of P450 enzymes involved in metabolism of verapamil in humans. Naunyn-Schmiedebergs Arch. Pharmacol. 348, 332-337 (1993).
-
(1993)
Naunyn-Schmiedebergs Arch. Pharmacol.
, vol.348
, pp. 332-337
-
-
Kroemer, H.K.1
Gautire, J.C.2
Beaune, P.3
Henderson, C.4
Wolf, C.R.5
Eichelbaum, M.6
-
27
-
-
0027460033
-
Identification and characterization of the cytochrome-P450 enzymes involved in the N-dealkylation of propaphenone - Molecular base for the interaction potential and variable disposition of active metabolites
-
S. Botach, J. C. Gautier, P. Beaune, M. Eichelbaum, and H. K. Kroemer: Identification and characterization of the cytochrome-P450 enzymes involved in the N-dealkylation of propaphenone - molecular base for the interaction potential and variable disposition of active metabolites. Mol. Pharmacol. 43, 120-126 (1993).
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 120-126
-
-
Botach, S.1
Gautier, J.C.2
Beaune, P.3
Eichelbaum, M.4
Kroemer, H.K.5
-
28
-
-
0027985726
-
Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test
-
L. Bertilsson, J. O. Carrillo, M. L. Dahl, A. Lierena, C. Alm, U. Bondesson, L. Lindstrom, I. R. Delarubia, S. Ramos, and J. Benitez: Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br. J. Clin. Pharmacol. 38, 471-473 (1994).
-
(1994)
Br. J. Clin. Pharmacol.
, vol.38
, pp. 471-473
-
-
Bertilsson, L.1
Carrillo, J.O.2
Dahl, M.L.3
Lierena, A.4
Alm, C.5
Bondesson, U.6
Lindstrom, L.7
Delarubia, I.R.8
Ramos, S.9
Benitez, J.10
-
30
-
-
0028008682
-
Role of human microsomal and human complementary DNA-expressed cytochrome-P4501A2 and cytochrome-P4503A4 in the bioactivation of aflatoxin-B(1)
-
E. P. Gallagher, L. C. Wienkers, P. L. Stapleton, K. L. Kunze, and D. L. Eaton: Role of human microsomal and human complementary DNA-expressed cytochrome-P4501A2 and cytochrome-P4503A4 in the bioactivation of aflatoxin-B(1). Cancer Res. 54, 101-108 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 101-108
-
-
Gallagher, E.P.1
Wienkers, L.C.2
Stapleton, P.L.3
Kunze, K.L.4
Eaton, D.L.5
-
31
-
-
0028360826
-
Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and man
-
R. J. Edwards, B. P. Murray, S. Murray, T. Schultz, D. Neubert, T. W. Gant, S. S. Thorgeirsson, A. R. Boobis, and D. S. Davies: Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and man. Carcinogenesis 15, 829-836 (1994).
-
(1994)
Carcinogenesis
, vol.15
, pp. 829-836
-
-
Edwards, R.J.1
Murray, B.P.2
Murray, S.3
Schultz, T.4
Neubert, D.5
Gant, T.W.6
Thorgeirsson, S.S.7
Boobis, A.R.8
Davies, D.S.9
-
32
-
-
0028069430
-
CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans
-
A. R. Boobis, A. M. Lynch, S. Murray, R. Delatorre, A. Solans, M. Farre, J. Segura, N. J. Gooderham, and D. S. Davies: CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. Cancer Res. 54, 89-94 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 89-94
-
-
Boobis, A.R.1
Lynch, A.M.2
Murray, S.3
Delatorre, R.4
Solans, A.5
Farre, M.6
Segura, J.7
Gooderham, N.J.8
Davies, D.S.9
|