Mineral changes in a transgenic mouse model for osteogenesis imperfecta

British Journal of Biomedical Science

Volumn 53, Issue 2, 1996, Pages 108-115

  Ali, S Y ^a  

^a ROYAL NATIONAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

Author keywords

Collagen; Mineral; Mouse; Osteogenesis imperfecta

Indexed keywords

CALCIUM; COLLAGEN TYPE 1; PHOSPHORUS; PROCOLLAGEN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE MINERAL; FEMUR; INFRARED SPECTROSCOPY; LONG BONE; MOUSE; NEWBORN; NONHUMAN; OSTEOGENESIS IMPERFECTA; PRIORITY JOURNAL; RIB; TRANSGENIC MOUSE; X RAY MICROANALYSIS;

ANIMALS; BONE AND BONES; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; MINERALS; OSTEOGENESIS IMPERFECTA;

EID: 0029957382     PISSN: 09674845     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Byers PH. Brittle bones - fragile molecules: disorders of collagen gene structure and expression. Trends Genet 1990; 6:293-300.
2. Aitchison K, Ogilvie D, Honeyman H, Thompson E, Sykes B. Homozygous osteogenesis imperfecta unlinked to collagen I genes. Hum Genet 1988; 78:233-6.
3. Pereira R, Khillan JS, Helminen HJ, Huma EL, Prockop DJ. Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral. J Clin Invest 1993; 91:709-16.
4. Sykes B. Bone disease cracks genetics. Nature 1990; 348:18-20.