Neutrophil-mediated injury in ischemic skin flaps: Amelioration of ischemic injury by cyclosporine in the rat

Annals of Plastic Surgery

Volumn 37, Issue 1, 1996, Pages 66-74

  Cetinkale, Oguz ^a,c   Bilgic, Levent ^b   Ayan, Fadil ^a   Kandilci, Ayten ^b  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; GRAFT FAILURE; GRAFT SURVIVAL; HISTOPATHOLOGY; ISCHEMIA; NECROSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN FLAP;

EID: 0029957329     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000637-199607000-00011     Document Type: Article

References (29)

1. Angel MF, Ramasastry SS, Swartz WM, et al. Augmentation of skin flap survival with allopurinol. Ann Plast Surg 1987;18:494-498
2. Angel MF, Ramasastry SS, Swartz WM, et al. The critical relationship between free radicals and degrees of ischemia. Evidence for tissue intolerance of marginal perfusion. Plast Reconstr Surg 1988;81:233-239
3. Kubes P, Hunter J, Granger N. Effects of cyclosporin A and FK506 on ischemia/reperfusion-induced neutrophil infiltration in the cat. Dig Dis Sci 1991;36:1469-1472
4. Lee C, Kerrigan CL. Neutrophil localization following reperfusion of ischemic skin flap. Plast Reconst Surg 1992;89:910-915
5. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989;320:365-376
6. Picard-Ami LA, Mackay A, Kerrigan CL. Pathophysiology of ischemic skin flaps: differences in xanthine oxidase levels among rats, pigs, and humans. Plast Reconstr Surg 1991;87:750-755
7. Rees R, Smith D, Li TD, et al. The role of xanthine oxidase and xanthine dehydrogenase in skin ischemia. J Surg Res 1994;56:162-167
8. Rees RS, Punch J, Shaheen K, et al. The stress response in skin: the role of neutrophil products in pre-conditioning. Plast Reconstr Surg 1993;92:110-117
9. De La Ossa JC, Malago M, Gewertz BL. Neutrophilendothelial cell binding in neutrophil-mediated tissue injury. J Surg Res 1992;53:103-107
10. McMillen MA, Huribal M, Sumpio B. Common pathway of endothelial-leukocyte interaction in shock, ischemia, and reperfusion. Am J Surg 1993;166:557-562
11. Simpson R, Alon R, Kobzik L, et al. Neutrophil and neutrophil-mediated injury in intestinal ischemiareperfusion. Ann Surg 1993;218:444-454
12. Schoenberg MH, Poch B, Younes M, et al. Involvement of neutrophils in postischaemic damage to the small intestine. Gut 1991;32:905-912
13. Vedder NB, Bucky LP, Lopez I, et al. Inhibition of neutrophil adherence improves survival of random flaps in rabbits. Surg Forum 1991;42:619-620
14. Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, et al. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 1993;55:1265-1272
15. Romson JL, Hook BG, Kunkel SL, et al. Reduction of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 1983;67:1016-1023
16. Vedder NB, Bucky LP, Richey NL, et al. Improved survival rates of random flaps in rabbits with a monoclonal antibody that blocks leukocyte adherence. Plast Reconstr Surg 1994;93:1035-1040
17. Shaheen KW, Punch JD, Rees RS, et al. Early role for neutrophils in skin flap failure. Surg Forum 1990;41:553-555
18. Im MJ, Manson PN, Bulkley GB, Hoopes JE. Effects of Superoxide dismutase and allopurinol on the survival of acute island skin flaps. Ann Surg 1985;201:357-359
19. Bucky LP, Vedder NB, Hong HZ, et al. Reduction of burn injury by inhibiting CD18-mediated leukocyte adherence in rabbits. Plast Reconstr Surg 1994;93:1473-1480
20. Hernandez LA, Grisham MB, Twohig B, et al. Role of neutrophils in ischemia-reperfusion induced microvascular injury. Am J Physiol 1987;253:H699-H703
21. Vedder NB, Fouty BW, Winn RK, et al. Role of neutrophils in generalized reperfusion injury associated with resuscitation from shock. Surgery 1989;106:509-516
22. Wakabayashi H, Karasawa Y, Maeba T, et al. Effect of FK506 and cyclosporine A on hepatic energy status in the rat after warm ischemia, as monitored by 31P nuclear magnetic resonance spectroscopy in vivo. Transplant Proc 1992;24:1993-1995
23. Kawano K, Kim YI, Kaketani K, et al. The beneficial effect of cyclosporine on liver ischemia in rats. Transplantation 1989;48:759-764
24. Kawano K, Kim YI, Goto S, et al. A protective effect of FK506 in ischemically injured rat livers. Transplantation 1991;52:143-145
25. Kucukcelebi A, Ozcan M. The beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps. Br J Plast Surg 1992;45:512-514
26. Shiga Y, Onodera H, Matsuo Y, et al. Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res 1992;595:145-148
27. Asako H, Kubes P, Baethge BA, et al. Reduction of leukocyte adherence and emigration by cyclosporine and L683,590 (FK506) in postcapillary venules. Transplantation 1992;54:686-690
28. Hayashi T, Nagasue N, Kohno H, et al. Evidence that cyclosporine pretreatment protects lysosomal membrane in liver ischemia in dogs. Transplantation 1989;47:924-925
29. Demling RH, Lalonde C. Early postburn lipid peroxidation: effect of ibuprofen and allopurinol. Surgery 1990; 107:85-93