Effects of protein kinase C on the Na+-H+ exchange in the cochlear outer hair cell

Acta Oto-Laryngologica

Volumn 116, Issue 6, 1996, Pages 828-832

  Ikeda, Katsuhisa ^a   Sunose, Hiroshi ^a   Takasaka, Tomonori ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclic AMP; Intracellular pH; Na+ H+ exchange; Phosphorylation; Protein kinase C

Indexed keywords

CYCLIC AMP; HYDROGEN; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL PH; COCHLEA; GUINEA PIG; HAIR CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0029957305     PISSN: 00016489     EISSN: None     Source Type: Journal    
DOI: 10.3109/00016489609137934     Document Type: Article

References (25)

1. + exchanger. J Membr Biol 1986; 90: 1-12.
2. + antiporter. Cell 1989; 56: 271-80.
3. Orlowski J, Kandasamy RA, Shull GE. Molecular cloning of putative members of the NHE exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat NHE exchanger NHE-1 and two structurally related proteins. J Biol Chem 1992; 267: 9331-9.
4. + exchanger isoform (NHE-3). J Biol Chem 1992; 267: 9340-6.
5. + exchanger. J Biol Chem 1993; 268: 11925-8.
6. Ikeda K, Saito Y, Nishiyama A, Takasaka T. Intracellular pH regulation in isolated outer hair cells of the guinea-pig. J Physiol 1992; 447: 627-48.
7. Kakehata S, Nakagawa T, Takasaka T, Akaike N. Cellular mechanism of acetylcholine-induced response in dissociated outer hair cells of guiniea-pig cochlea. J Physiol 1993; 463: 227-44.
8. Kakehata S, Yamamoto T, Akaike N et al. Acetylcholine activates distinct signaling pathways through pertussis toxin- and cholera toxin-sensitive G proteins in guinea-pig outer hair cells. Assoc Res Otolaryngol Abstr 1994; 17: 127.
9. Kolesnikov SS, Rebrik TI, Zhainazarov AB, Tavartkiladze GA, Kalamkarov GR. A cyclic-AMP-gated conductance in cochlear hair cells. FEBS Lett 1990; 290: 167-70.
10. + antiport. J Gen Physiol 1984; 83: 341-69.
11. 2+ exchange in the isolated cochlear outer hair cells of the guinea-pig studied by fluorescence image microscopy. Pflugers Arch 1992; 420: 493-9.
12. Sunose H, Ikeda K, Saito Y, Nishiyama A, Takasaka T. Membrane potential measurement in isolated outer hair cells of the guinea pig cochlea using conventional microelectrodes. Hear Res 1992; 62: 237-44.
13. Boron WF, Russell JM. Stoichiometry and ion dependencies of the intracellular-pH-regulatory mechanism in squid giant axons. J Gen Physiol 1983; 67: 91-112.
14. 2+ and protein kinase C. J Biol Chem 1990; 265: 21068-74.
15. + exchanger. Annu Rev Physiol 1985; 47:545-60.
16. + antiporter, a glycoprotein of 110 kD. Science 1990; 247: 723-6.
17. + exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation. J Biol Chem 1994; 269: 5583-8.
18. + exchangers stably expressed in a fibroblast cell line. J Biol Chem 1993; 268: 25527-35.
19. + exchanger (NHE3): resistance to amiloride and inhibition by protein kinase C. Proc Natl Acad Sci USA 1993; 90: 9110-4.
20. + exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localization. J Clin Invest 1994; 93: 106-13.
21. + exchanger (NHE-2). Proc Natl Acad Sci USA 1993; 90: 3938-42.
22. + exchanger. EMBO J 1991; 10: 1957-67.
23. Rothstein A. The Na/H exchange system in cell pH and volume control. Rev Physiol Biochem Pharmacol 1989; 112: 235-57.
24. + exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation. Biochem Biophys Acta 1989; 988: 73-97.
25. Ikeda K, Sunose H, Takasaka T. Ion trasnport mechanisms in the outer hair cell of the mammalian cochlea. Prog Neurobiol 1994; 42: 703-17.