Genetic manipulation of the pathway for diacetyl metabolism in Lactococcus lactis

Applied and Environmental Microbiology

Volumn 62, Issue 7, 1996, Pages 2641-2643

  Swindell, Simon R ^a   Benson, Kim H ^a   Griffin, Hugh G ^a   Renault, P ^b   Ehrlich, S Dusko ^b   Gasson, Michael J ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b CEMAGREF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 BUTANEDIONE; ACETOLACTATE SYNTHASE; CITRIC ACID;

ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BACTERIAL MUTATION; BACTERIUM MUTANT; DELETION MUTANT; GENE DELETION; LACTOCOCCUS LACTIS; NONHUMAN; STRAIN DIFFERENCE;

BACTERIA (MICROORGANISMS); LACTOCOCCUS LACTIS; STREPTOCOCCUS;

EID: 0029957056     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.62.7.2641-2643.1996     Document Type: Article

References (21)

1. Bassit, N., C.-Y. Boquien, D. Picque, and G. Corrieu. 1993. Effect of initial oxygen concentration on diacetyl and acetoin production by Lactococcus lactis subsp. lactis biovar diacetylactis. Appl. Environ. Microbiol. 59:1893-1897.
2. Benson, K. H., J.-J. Godon, P. Renault, H. G. Griffin, and M. J. Gasson. 1996. Effect of ilvBN-encoded α-acetolactate synthase expression on diacetyl production in Lactococcus lactis. Appl. Microbiol. Biotechnol. 45:107-111.
3. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
4. Gasson, M. J. 1983. Plasmid complements of Streptococcus lactis NCDO712 and other lactic streptococci after protoplast-induced curing. J. Bacteriol. 154:1-9.
5. Godon, J.-J., M.-C. Chopin, and S. D. Ehrlich. 1992. Branched-chain amino acid biosynthesis genes in Lactococcus lactis subsp. lactis. J. Bacteriol. 174: 6580-6589.
6. Godon, J.-J., C. Delorme, J. Bardowski, M.-C. Chopin, S. D. Ehrlich, and P. Renault. 1993. Gene inactivation in Lactococcus lactis: branched-chain amino acid biosynthesis. J. Bacteriol. 175:4383-4390.
7. Goupil, N., G. Corthier, S. D. Ehrlich, and P. Renault. 1996. Imbalance of leucine flux in Lactococcus lactis and its use for the isolation of diacetyl-overproducing strains. Appl. Environ. Microbiol. 62:2636-2640.
8. Griffin, H. G. 1994. Direct PCR screening of lambda and cosmid libraries, p. 53-57. In H. G. Griffin and A. M. Griffin (ed.), PCR protocols: current innovations. CRC Press, Boca Raton, Fla.
9. Griffin, H. G., K. J. I'Anson, and M. J. Gasson. 1993. Rapid isolation of genes from bacterial lambda libraries by direct PCR screening. FEMS Microbiol. Lett. 112:49-54.
10. Hugenholtz, J. 1993. Citrate metabolism in lactic acid bacteria. FEMS Microbiol. Rev. 12:165-178.
11. Jordan, K. N., and T. M. Cogan. 1988. Production of acetolactate by Streptococcus diacetylactis and Leuconostoc spp. J. Dairy Res. 55:227-238.
12. Monnet, C., V. Phalip, P. Schmitt, and C. Diviès. 1994. Comparison of α-acetolactate synthase and α-acetolactate decarboxylase in Lactococcus spp. and Leuconostoc spp. Biotechnol. Lett. 16:257-262.
13. Phalip, V., C. Monnet, P. Schmitt, P. Renault, J.-J. Godon, and C. Diviès. 1994. Purification and properties of the α-acetolactate decarboxylase from Lactococcus lactis subsp. lactis NCDO 2118. FEBS Lett. 351:95-99.
14. Pien, J., J. Baisse, and R. Martin. 1937. Le dosage du diacétyl dans les buerres. Lait 17:673-698.
15. Renault, P., J.-J. Godon, N. Goupil, C. Delorme, G. Corthier, and S. D. Ehrlich. 1995. Metabolic operons in lactococci. Dev. Biol. Stand. 85:431-441.
16. Snoep, J. L., M. J. Teixeira de Mattos, M. J. C. Starrenburg, and J. Hugenholtz. 1992. Isolation, characterization, and physiological role of the pyruvate dehydrogenase complex and α-acetolactate synthase of Lactococcus lactis subsp. lactis bv. diacetylactis. J. Bacteriol. 174:4838-4841.
17. Starrenburg, M. J. C., and J. Hugenholtz. 1991. Citrate fermentation by Lactococcus and Leucanostoc spp. Appl. Environ. Microbiol. 57:3535-3540.
18. Umbarger, H. E. 1987. Biosynthesis of branched-chain amino acids, p. 352-367. In F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella typhimurium: cellular and molecular biology. American Society for Microbiology, Washington, D.C.
19. van de Guchte, M. 1991. Ph.D. thesis. University of Groningen, Groningen, The Netherlands.
20. van der Vossen, J. M. B. M., D. van der Lelie, and G. Venema. 1987. Isolation and characterization of Streptococcus cremoris Wg2-specific promoters. Appl. Environ. Microbiol. 53:2452-2457.
21. Westerfeld, W. W. 1945. A colorimetric determination of blood acetoin. J. Biol. Chem. 161:495-502.