Grb10: A new substrate of the insulin-like growth factor I receptor

Cancer Research

Volumn 56, Issue 14, 1996, Pages 3165-3167

  Morrione, Andrea ^a   Valentinis, Barbara ^a   Li, Shiwei ^a,c   Ooi, James Y T ^b   Margolis, Ben ^b   Baserga, Renato ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c Cascade Biologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ISOLATION; REGULATORY MECHANISM;

BINDING SITES; GRB10 ADAPTOR PROTEIN; HUMANS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEINS; RECEPTOR, IGF TYPE 2; SRC HOMOLOGY DOMAINS;

EID: 0029957011     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Liu, J-P., Baker, J., Perkins, A. S., Robertson, E. J , and Efstratiadis, A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (igf-1) and type 1 IGF receptor (igf1r). Cell, 75: 59-72, 1993.
2. Baker, J., Liu, J-P., Robertson, E. J., and Efstratiadis, A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell, 73: 73-82, 1993.
3. Sell, C., Dumenil, G., Deveaud, C., Miura, M , Coppola, D., DeAngelis, T., Rubin, R., Efstratiadis, A., and Baserga, R. Effect of a null mutation of the type 1 IGF receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol., 14: 3604-3612, 1994.
4. Sell, C., Rubini, M., Rubin, R., Liu, J-P., Efstratiadis, A , and Baserga, R. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type-1 IGF receptor. Proc. Natl. Acad. Sci. USA, 90: 11217-11221, 1993
5. Baserga, R. The insulin-like growth factor 1 receptor: a key to tumor growth? Cancer Res., 55: 249-252, 1995.
6. Harrington, E. A., Bennett, M. R., Fanidi, A., and Evan, G. I. c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J , 13: 3286-3295, 1994.
7. Resnicoff, M., Abraham, D., Yutanawiboonchai, W., Rotman, H., Kajstura, J , Rubin, R., Zoltick, P , and Baserga, R. The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo. Cancer Res., 55: 2463-2469, 1995.
8. Myers, M. G., Sun, X. J., Cheatham, B., Jachna, B. R , Glasheen, E. M., Backer, J. M., and White, M. F. IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3′-kinase. Endocrinology, 132: 1421-1430, 1993.
9. Araki, E., Lipes, M. A., Patti, M. E., Bruning, J. C., Haag, B , III, Johnson, R S., and Kahn, C. R. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature (Lond.), 372: 186-190, 1994 .
10. Sasaoka, T., Rose, D. W., Jhun, B H., Saltiel, A. R., Draznini, B., and Olefsky, J. M. Evidence for a functional role of Shc proteins in mitogenic signaling by insulin, insulin-like growth factor 1 and epidermal growth factor J. Biol Chem , 269: 13689-13694, 1994.
11. Skolnik, E. Y., Batzer, A., Li, N., Lee, C. H., Lowenstein, E., Mohammadi, M., Margolis, B., and Schlessinger, J. The function of Grb2 in linking the insulin receptor to ras signaling pathways. Science (Washington DC), 260: 1953-1955, 1993
12. Baltensperger, K., Kozma, L M., Cherniack, A. D., Klarlund, J. K., Chawla, A., Banerjee, U., and Czech, M. P. Binding of the ras activator son of sevenless to insulin receptor substrate-1 signaling complexes. Science (Washington DC), 260: 1950-1952, 1993.
13. Ooi, J., Yajnik, V , Immanuel, D., Gordon, M., Moskow, J. J., Buchberg, A. M , and Margolis, B. The cloning of Grb10 reveals a new family of SH2 domains proteins. Oncogene, 10: 1621-1630, 1995.
14. Surmacz, E., Sell, C., Swantek, J , Kato, H., Roberts, C T., Jr , LeRoith, D., and Baserga, R. Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor I receptor. Exp. Cell Res., 218: 370-380, 1995.
15. Liu, D., Zong, C., and Wang, L. H. Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions. J. Virol , 67: 6835-6840, 1993.
16. Hongo, A., D'Ambrosio, C., Miura, M., Morrione, A., and Baserga, R. Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor. Oncogene, 12: 1231-1238, 1996.
17. 1 cyclin-dependent kinases. Cell, 75: 805-816, 1993.
18. Vojtek, A., Hollenberg, S. M., and Cooper, J. A. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell, 74: 205-214, 1993.
19. Chien, C. T , Bartel, P. L., Sternglanz, R., and Fields, S. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad Sci USA, 88: 9578-9582, 1991.
20. Ullrich, A., Gray, A , Tam, A. W., Yang-Feng, T., Tsubokawa, M., Collins, C , Henzel, W , Le Bon, T., Kahuria, S., Chen, E., Jakobs, S., Francke, U , Ramachandran, J., and Fujita-Yamaguchi, Y. Insulin-like growth factor I receptor primary structure, comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J., 5: 503-512, 1986.
21. Craparo, A., O'Neill, T. J., and Gustafson, T. A Non-SH2 domains with insulin receptor substrate-1 and SHC mediate their phosphotyrosine- dependent interaction with the NPEY motif of the insulin-like growth factor I receptor. J. Biol. Chem , 270: 15639-15643, 1995.
22. Tartare-Deckert, S., Sawka-Verhelle, D., Murdaca, J , and Van Obberghen, E. Evidence for a differential interaction of Shc and the insulin receptor substrate-1 (IRS-1) with the insulin-like growth factor I (IGF-I) receptor in the yeast two-hybrid system. J. Biol. Chem., 270 23456-23460, 1995.
23. Coppola, D., Ferber, A., Miura, M., Sell, C., D'Ambrosio, C., Rubin, R., and Baserga, R. A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol. Cell Biol., 14: 4588-4595, 1994
24. Li, S., Ferber, A., Miura, M., and Baserga, R. Mitogenicity and transforming activity of the insulin-like growth factor I receptor with mutations in the tyrosine kinase domain. J. Biol Chem , 269: 32558-32564, 1994.
25. Miura, M., Li, S., and Baserga, R Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells. Cancer Res , 55: 663-667, 1995.
26. Miura, M., Surmacz, E., Burgaud, J. L., and Baserga, R. Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor. J. Biol. Chem., 270: 22639-22644, 1995.
27. Li, S , Resnicoff, M., and Baserga, R. Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor I receptor. J. Biol. Chem , 271: 12254-12260, 1996.
28. Liu, F., and Roth, R. A. Grb-IR: a SH2 domain-containing protein that binds to the insulin receptor and inhibits its function Proc. Natl. Acad. Sci USA, 92: 10287-10291, 1995.
29. Hansen, H , Svansson, U , Zhu, J., Laviola, L. Giorgino, F., Wolf, G., Smith, R. J., and Riedel, H Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus. J. Biol. Chem., 271: 8882-8886, 1996.