Reverse transcriptase/polymerase chain reaction detection of cytokeratin-19 mRNA in bone marrow and blood of breast cancer patients

Journal of Cancer Research and Clinical Oncology

Volumn 122, Issue 11, 1996, Pages 679-686

  Krüger, William ^a   Krzizanowski, Cordula ^a   Holweg, Michael ^a   Stockschläder, Marcus ^a   Kröger, Nicolaus ^a   Jung, Roman ^a   Mross, Klaus ^b   Jonat, Walter ^a   Zander, Axel R ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Clinic for Tumorbiology and Medical Oncology   (Germany)

Author keywords

Breast cancer; Micrometastases; Minimal residual disease; RT PCR

Indexed keywords

CYTOKERATIN;

ARTICLE; BLOOD; BONE MARROW METASTASIS; BREAST CANCER; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MINIMAL RESIDUAL DISEASE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BASE SEQUENCE; BONE MARROW; BONE MARROW NEOPLASMS; BREAST NEOPLASMS; CONSENSUS SEQUENCE; FEMALE; GENE EXPRESSION; HUMANS; KERATINS; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; RNA, MESSENGER; RNA, NEOPLASM; SEQUENCE ALIGNMENT; TUMOR CELLS, CULTURED;

EID: 0029956813     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01209032     Document Type: Article

References (32)

1. Antman K, Ayash L, Elias A, Wheeler C, Hunt M, Eder JP, Teicher BA, Critchlow J, Bibbo J, Schnipper LE, Frei E (1992) A phase II study of high-dose cyclophosphamide, thiotepa, and carboplatin with autologous marrow support in women with measurable advanced breast cancer responding to standard-dose therapy. J Clin Oncol 10:102-110
2. Bader BL, Magin TM, Hatzfeld M, Franke WW (1986) Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein. EMBO J 5:1865-1875
3. Bártek J, Bártkova J, Schneider J, Taylor-Papadimitriou J, Kovarik J, Rejthar A (1986) Expression of monoclonal antibody-defined epitopes of keratin 19 in human tumours and cultured cells. Eur J Cancer Clin Oncol 22:1441-1452
4. Bonadonna G, Valagussa P (1981) Dose-response effect of adjuvant chemotherapy in breast cancer. N Engl J Med 304:10-15
5. Burchill SA, Bradbury MF, Pittman K, Southgate J, Smith B, Selby P (1995) Detection of epithelial cancer cells in peripheral blood by reverse transriptase-polymerase chain reaction. Br J Cancer 71:278-281
6. Chomczynski P, Sacchi N (1987) Single-step method of RNA-isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
7. Cote RJ, Rosen PP, Old LJ, Osborne MP (1991) Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastasis. J Clin Oncol 9:1749-1756
8. Crescenzi M, Seto M, Herzig GP, Weiss PD, Griffith RC, Korsmeyer, SJ (1988) Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease. Proc Natl Acad Sci USA 85:4869-4873
9. Datta YH, Adams PT, Drobyski WR, Ethier SP, Terry VH, Roth MS (1994) Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 12:475-482
10. Dearnaley DP, Omerod MG, Sloane JP (1991) Micrometastases in breast cancer: Long-term follow-up of the first patient cohort. Eur J Cancer 27:236-239
11. Diel IJ, Kaufmann M, Goerner R, Costa SD, Kaul S, Bastert G (1992) Detection of tumour cells in bone marrow of patients with primary breast cancer: A prognostic factor for distant metastasis. J Clin Oncol 10:1534-1539
12. Eiermann W, Harbeck N, Untch M (1990) Möglichkeiten der Immunzytochemie am Beispiel der Knochenmarkaspirationszytologie bei Mammakarzinompatientinnen. Gynäkologe 23:358-364
13. Gerhard M, Juhl H, Kalthoff H, Schreiber HW, Wagener C, Neumaier M (1994) Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 12:725-729
14. Harris JR, Lippman ME, Veronesi U, Willett W (1992) Breast Cancer. [parts I, II, III. N Engl J Med 327:319-328, 390-398, 473-480
15. Innis MA, Gelfand DH, Sninsky J, White TJ (1989) PCR-protocols. A guide to methods and applications. Academic Press, New York
16. Joshi SS, Kessinger A, Mann SL, Stevenson M, Weisenburger DD, Vaughan WP, Armitage JO, Sharp JG (1987) Detection of malignant cells in histologically normal bone marrow using culture techniques. Bone Marrow Transpl 1:303-310
17. Krüger WH, Stockschläder M, Zander AR (1994) Detection of epithelial specific RNA in blood and bone marrow with a RT-based polymerase chain reaction. Proc Annu Meet Am Soc Clin Oncol 13:A74
18. Maniatis T, Fritsch EF, Sambrook J (1989) Molecular cloning:a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
19. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24
20. Mullis KB, Faloona FA (1987) Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol 155:335-350
21. Neville AM (1991) Breast cancer micrometastases in lymph nodes and bone marrow are prognostically important. Ann Oncol 2:13-14
22. Ponte P, Ng SY, Engel J, Gunning P, Kedes L (1984) Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res 12:1687-1696
23. Ross AA, Cooper BW, Lazarus HM, MacKay W, Moss TJ, Ciobanu N, Tallman MS, Kennedy MJ, Davidson N, Sweet DS, Winter C, Jansen J, Akard L, Copelan E, Kahn DG, Warner NE (1992) Comparison of tumor cell contamination in peripheral blood stem cell collections (PBSC) and bone marrow (BM) in patients with advanced breast cancer (ABC) using immunocytochemistry (ICC): evidence for clonogenicity of occult metastases. Blood 80:235a
24. Savtchenko ES, Schiff TA, Jiang CK, Freedberg IM, Blumenberg M (1988) Embryonic expression of the human 40-kD keratin: evidence from a processed pseudogene sequence. Am J Hum Genet 43:630-637
25. Schlimok G, Funke I, Holzmann B, Göttlinger G, Schmidt G, Häuser H, Swierkot S, Warnecke HH, Schneider B, Koprowsky H, Riethmüller G (1987) Micrometastatic cancer cells in bone marrow:In-vitro detection with anti-cytokeratin and in-vivo labeling with anti-17-1A monoclonal antibodies. Proc Natl Acad Sci USA 84:8672-8676
26. Schoenfeld A, Luqmani Y, Smith D, O'Reilly S, Shousha S, Sinett HD, Coombes RD (1994) Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction. Cancer Res 54:2986-2990
27. Sharp JG, Vaughan WP, Kessinger A, Mann SL, DeBoer JM, Sanger WG, Weisenburger DD (1990) Significance of detection of tumor cells in hematopoetic stem cell harvests of patients with breast cancer. In: Dicke KA et al. (eds) Proceedings of the 5th International. Symposium on Autologous Bone Marrow Transplantation. The University Medical Center, Omaha, NE
28. Smith B, Selby P, Southgate J, Pittman K, Bradley C, Blair GE (1991) Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet 338:1227-1229
29. Stasiak PC, Lane EB (1987) Sequence of cDNA coding for human keratin 19. Nucleic Acids Res 15:10058
30. Tracy TE, Mulcahy LS (1991) A simple method for direct automated sequencing of PCR fragments. Biotechniques 11:68
31. Van de Vijver M, Nusse R (1991) The molecular biology of breast cancer. Biochim Biophys Acta 1072:33-50
32. Williams SF, Gilewski T, Mick R, Bitran JD (1992) High-dose consolidation therapy with autologous stem cell rescue in stage IV breast cancer: Follow-up report. J Clin Oncol 10:1743-1747