Nitric oxide and hypertension in 1995

Current Opinion in Nephrology and Hypertension

Volumn 5, Issue 2, 1996, Pages 174-180

  Dominiczak, Anna F ^a   Bohr, David F ^b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; VASODILATOR AGENT;

BRAIN; DRUG EFFECT; DRUG RELEASE; ENDOTHELIUM; HUMAN; HYPERTENSION; KIDNEY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; TISSUE LEVEL; VASCULAR SMOOTH MUSCLE;

ANIMALS; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 0029956216     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-199603000-00014     Document Type: Review

References (64)

1. Arnal J-F, Michel J-B, Harrison DG: Nitric oxide in the pathogenesis of hypertension. Curr Opin Nephrol Hypertens 1995, 4:182-188.
2. Dominiczak AF, Bohr DF: Nitric oxide and its putative role in hypertension. Hypertension 1995, 25:1202-1211.
3. Nava E, Lüscher TF: Endothelium-derived vasoactive factors in hypertension: nitric oxide and endothelin. J Hypertens 1995, 13(suppl 2):539-548.
4. Vanhoutte PM, Boulanger CM: Endothelium-dependent responses in hypertension. Hypertens Res 1995, 18:87-98.
5. van Zwieten PA, Safar M, Laurent S, Pfaffendorf M, Hendriks MGC, Bruning TA: New insights into the role of endothelial dysfunction in hypertension. J Hypertens 1995, 13:713-716.
6. Förstermann U, Closs EI, Pollock JS, Nakane M, Schwarz P, Gath I, Kleinert H: Nitric oxide synthase isozymes: characterization, purification, molecular cloning, and functions. Hypertension 1994, 23:1121-1131.
7. Snyder SH: No endothelial NO. Nature 1995, 377:196-197. Knockout mice have been prepared for each of the three isozymes of NOS.
8. Huang PL, Dawson TM, Bredt DS, Snyder SH, Fishman MC: Targeted disruption of the neuronal nitric oxide synthase gene. Cell 1993, 75:1273-1286.
9. Cabrera C, Bohr D: The role of nitric oxide in a central control of blood pressure. Biochem Biophys Res Commun 1995, 206:77-81.
10. Wei X, Charles IG, Smith A, Ure J, Feng G, Huang F, Xu D, Muller W, Moncada S, Liew FY: Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 1995, 375:408-411.
11. Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC: Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995, 377:239-242. Mice in which the gene encoding eNOS was disrupted became hypertensive, demonstrating that eNOS mediates basal vasodilation.
12. Knowles RG, Palacios M, Palmer RMJ, Moncada S: Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc Natl Acad Sci U S A 1989, 86:5159-5162.
13. 2+ response to acetylcholine in endothelial cells from aorta of aldosterone-salt hypertensive rats. Am J Hypertens 1995, 8:404-408.
14. Kanai AJ, Strauss HC, Truskey GA, Crews AL, Grunfeld S, Malinski T: Shear stress induces ATP-independent transient nitric oxide release from vascular endothelial cells, measured directly with a porphyrinic microsensor. Circ Res 1995, 77:284-293. Shear stress on endothelial cells increases intracellular calcium, which stimulates the release of NO.
15. Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH: Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res 1994, 74:349-353.
16. Palmer R, Aston D, Moncada S: Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988, 333:664-666.
17. Wakabayashi Y, Yamada E, Yoshida T, Takahashi H: Deficiency of endogenous arginine synthesis provokes hypertension by exhausting substrate arginine for nitric oxide synthesis. Biochem Biophys Res Commun 1994, 205:1391-1398.
18. Higashi Y, Oshima T, Ozono R, Watanabe M, Matsuura H, Kajiyama G: Effects of L-arginine infusion on renal hemodynamics in patients with mild essential hypertension. Hypertension 1995, 25:898-902.
19. Pucci ML, Dick LB, Miller KB, Smith CJ, Nasjletti A: Enhanced responses to L-arginine in aortic rings from rats with angiotensin-dependent hypertension. J Pharmacol Exp Ther 1995, 274:1-7.
20. Deng X, Welch WJ, Wilcox CS: Renal vasodilation with L-arginine: effects of dietary salt. Hypertension 1995, 26:256-262.
21. Jin JS, D'Alecy LG: Stimulation of endogenous nitric oxide pathway by L-arginine reduces declamp mortality and attenuates hypertension associated with aortic cross-clamp-induced hindlimb ischemia in rats. Hypertension 1995, 26:406-412.
22. Rubanyi G, Ho E, Cantor E, Lumma W, Parker B: Cytoprotective function of nitric oxide: inactivation of superoxide radicals produced by human leukocytes. Biochem Biophys Res Commun 1991, 181:1392-1397.
23. Grunfeld S, Hamilton CA, Mesaros S, McClain SW, Dominiczak AF, Bohr DF, Malinski T: Role of superoxide in the depressed nitric oxide production by endothelial cells from genetically hypertensive rats. Hypertension 1995, 26:854-857. Excess production of superoxide appears to be responsible for the depressed release of NO in endothelial cells of SHRSP.
24. Nakazono K, Watanabe M, Matsuno K, Sasaki J, Sato T, Inoue M: Does superoxide underlie the pathogenesis of hypertension? Proc Natl Acad Sci U S A 1991, 88:10045-10048.
25. Vega GW, Roson MI, Bellver A, Celentano MM, de la Riva JJ: Nitric oxide and superoxide anions in vascular reactivity of renovascular hypertensive rats. Clin Exp Hypertens 1995, 17:817-835.
26. Ito II, Torli M, Suzuki T: Decreased superoxide dismutase activity and increased superoxide anion production in cardiac hypertrophy of spontaneously hypertensive rats. Clin Exp Hypertens 1995, 17:803-816.
27. Chen G, Wilson R, Boyd P, McKillop JH, Leitch C, Walker JJ, Burdon RH: Normal superoxide dismutase (SOD) gene in pregnancy-induced hypertension: is the decreased SOD activity a secondary phenomenon? Free Radical Res 1994, 21:59-66.
28. McCabe RD, Bakarich MA, Srivastava K, Young DB: Potassium inhibits free radical formation. Hypertension 1994, 24:77-82.
29. Taddei S, Mattei P, Virdis A, Sudano I, Ghiadoni L, Salvetti A: Effect of potassium on vasodilation to acetylcholine in essential hypertension. Hypertension 1994, 23:485-490.
30. Cabrera CI, Bealer SL, Bohr DF: Central depressor action of nitric oxide is deficient in genetic hypertension. Am J Hypertens (in press).
31. Huang BS, Leenen FHH: Brain 'ouabain' mediates the sympatho-excitatory and hypertensive effects of high sodium intake in Dahl salt-sensitive rats. Circ Res 1994, 74:586-595.
32. Gomez-Sanchez EP, Gomez-Sanchez CE: Effect of central infusion of benzamil on Dahl S rat hypertension. Am J Physiol 1995, 269:H1044-H1047.
33. Gomez-Sanchez EP, Gomez-Sanchez CE: Effect of central amiloride infusion on mineralocorticoid hypertension. Am J Physiol 1994, 267:E754-E758.
34. Light DB, Schwiebert EM, Karlson KH, Stanton BA: Atrial natriuretic peptide inhibits a cation channel in renal inner medullary collecting duct cells. Science 1989, 243:383-385.
35. Huang M, Leblanc M, Hester R: Systemic and regional hemodynamics after nitric oxide synthase inhibition: role of a neurogenic mechanism. Am J Physiol 1994, 267:R84-R88.
36. Cunha R, Cabrai A, Vasquez E: Evidence that the autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats. Am J Hypertens 1993, 6:806-809.
37. Zanzinger J, Czachurski J, Seller H: Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res 1994, 75:1073-1077.
38. Ruilope LM, Lahera V, Rodicio JL, Romero JC: Participation of nitric oxide in the regulation of renal function: possible role in the genesis of arterial hypertension. J Hypertens 1994, 12:625-631.
39. Fitzgerald SM, Evans RG, Christy IJ, Anderson WP: Nitric oxide synthase blockade and renal vascular response to norepinephrine and endothelin-1 in conscious dogs. J Cardiovasc Pharmacol 1995, 25:979-985.
40. Stoos BA, Carretero OA, Garvin JL: Endothelial-derived nitric oxide inhibits sodium transport by affecting apical membrane channels in cultured collecting duct cells. J Am Soc Nephrol 1994, 4:1855-1860.
41. Beierwaltes WH: Selective neuronal nitric oxide synthase inhibition blocks furosemide-stimulated renin secretion in vivo. Am J Physiol 1995, 269:F134-F139. NO release by the macula densa regulates renin release by the juxtaglomerular apparatus.
42. Ono H, Ono Y, Frohlich ED: Nitric oxide synthase inhibition in spontaneously hypertensive rats: systemic, renal, and glomerular hemodynamics. Hypertension 1995, 26:249-255.
43. Rees DD, Palmer RMJ, Moncada S: Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci U S A 1989, 86:3375-3378.
44. G-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo? Biochem Biophys Res Commun 1989, 160:881-886.
45. G-nitro-L-arginine methyl ester in conscious, long Evans rats. Br J Pharmacol 1990, 101:825-631.
46. Huang M, Manning RD, LeBlanc MH, Hester RL: Overall hemodynamic studies after the chronic inhibition of endothelial-derived nitric oxide in rats. Am J Hypertens 1995, 8:358-364. Chronic (4-weeks) treatment with L-NAME results in increased mean arterial pressure and peripheral resistance as well as widespread decrease in regional blood flow.
47. Dunn WR, Gardiner SM: No evidence for vascular remodeling during hypertension induced by chronic inhibition of nitric oxide synthase in Brattleboro rats. J Hypertens 1995, 13:849-857. Chronic oral administration of L-NAME produces hypertension without vascular hypertrophy or remodelling of mesenteric resistance arteries.
48. Arnal JF, Amrani AI, Chatellier G, Menard J, Michel JB: Cardiac weight in hypertension induced by nitric oxide synthase blockade. Hypertension 1993, 22:380-387.
49. Rhaleb NE, Yang XP, Scili AG, Carretero OA: Role of kinins and nitric oxide in the antihypertrophic effect of ramipril. Hypertension 1994, 23:865-868.
50. Dominiczak AF, Devlin AM, Clark J, Bohr DF, Reid JL: Angiotensin II and cell cycle in genetic hypertension [Abstract]. Hypertension 1995, 26:543.
51. Sander M, Hansen PG, Victor RG: Sympathetically mediated hypertension caused by chronic inhibition of nitric oxide. Hypertension 1995, 26:691-695. L-NAME-induced hypertension is, at least partly, sympathetically mediated.
52. Cockroft JR, Chowienczyk PJ, Benjamin N, Ritter JM: Preserved endothelium-dependent vasodilatation in patients with essential hypertension. N Engl J Med 1994, 330:1036-1040.
53. Falloon BJ, Heagerty AM: In vitro perfusion studies of human resistance artery function in essential hypertension. Hypertension 1994, 24:16-23.
54. Deng LY, Li JS, Schiffrin EL: Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats. Clin Sci 1995, 88:611-622. An elegant demonstration of the presence of endothelium-derived contracting factor in small arteries from the SHR and its absence in small arteries from subjects with essential hypertension.
55. Vallance P, Patton S, Bhagat K, MacAllister R, Radomski M, Moncada S, Malinski T: Direct measurement of nitric oxide in human beings. Lancet 1995, 346:153-154. The first demonstration of the use of electrochemical microsensors to detect NO signals in blood vessels in vivo.
56. McCarthy AL, Woolfson RG, Raju SK, Poston L: Abnormal endothelial cell function of resistance arteries from women with pre-eclampsia. Am J Obstet Gynecol 1993, 168:1323-1330.
57. Delacretaz E, DeQuay N, Waeber B, Vial Y, Schulz PE, Burnier M, Brunner HR, Bossart H, Schaad NC: Differential nitric oxide synthase activity in human platelets during normal pregnancy and pre-eclampsia. Clin Sci 1995, 88:607-610. The first demonstration of an increase in NO activity in human tissue during pregnancy and almost no increase during pre-eclampsia.
58. Baker PN, Davidge ST, Roberts JM: Plasma from women with pre-eclampsia increased endothelial cell nitric oxide production. Hypertension 1995, 26:244-248.
59. Kauser K, Rubanyi G: Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension 1995, 25:517-523. Demonstration of significant sex differences in endothelial dysfunction in the SHR.
60. Weiner C, Lizasoain I, Baylis SA, Knowles RG, Carles IG, Moncada S: Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci U S A 1994, 91:5212-5216.
61. Bell DR, Rensberger HJ, Koritnik DR, Koshy A: Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries. Am J Physiol 1995, 265:H377-H383.
62. McIntyre M, Hamilton CA, McPherson K, Reid JL, Dominiczak AF: The effect of gender on basal nitric oxide release in a model of genetic hypertension [Abstract]. J Hypertens (in press).
63. Rosselli M, Imthurn B, Macas E, Keller PJ, Dubey RK: Circulating nitrite/nitrate levels increase with follicular development: indirect evidence for estradiol mediated NO-release. Biochem Biophys Res Commun 1994, 202:1543-1552.
64. 3 levels in post-menopausal women.