Ketamine for analgosedative therapy in intensive care treatment of head-injured patients

Acta Neurochirurgica

Volumn 138, Issue 10, 1996, Pages 1193-1199

  Kolenda, H ^a,b   Gremmelt, A ^a   Rading, S ^a   Braun, U ^a   Markakis, E ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Clinical study; Head injury; Ketamine; Midazolam

Indexed keywords

ANESTHETIC AGENT; FENTANYL; HYPNOTIC SEDATIVE AGENT; KETAMINE; MIDAZOLAM; NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ADULT; AGED; ANALGESIA; ARTICLE; BRAIN PERFUSION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FOOD INTAKE; HEAD INJURY; HEART ARREST; HUMAN; INTENSIVE CARE; INTRACRANIAL PRESSURE; MULTIPLE ORGAN FAILURE; PERFUSION PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEDATION;

ADOLESCENT; ADULT; AGED; BLOOD PRESSURE; BRAIN INJURIES; CONSCIOUS SEDATION; CRITICAL CARE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FENTANYL; GLASGOW COMA SCALE; HEART RATE; HUMANS; INTRACRANIAL PRESSURE; KETAMINE; MALE; MIDAZOLAM; MIDDLE AGED; PROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0029955922     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01809750     Document Type: Article

References (34)

1. Adams HA, Biscoping J, Russ W. Hempelmann G (1990) The use of ketamine-midazolam combination for sedation and analgesia in intensive care patients. In: Domino FF (ed) Status of ketamine in anesthesiology. NPP, Ann Arbor, pp 453-463
2. Adams HR, Parker JL, Mathew BP (1977) The influence of ketamine on ionotropic and chronotropic responsiveness of heart muscle. J Pharmacol Exp Ther 201: 771-783
3. Bond AC, Davie CK (1974) Ketamine and pancuronium for the shocked patient. Anaesthesia 29: 59-62
4. Bunegin L, Ritter E. Albin MS (1992) Effect of low dose ketamine on free radical formation in the brain during hypoxia. Anesthesiology 77: A710-A714
5. Cartwright PD, Pingel SM (1984) Midazolam and diazepam in ketamine anaesthesia. Anaesthesia 59: 439-442
6. Cavazzutti M, Porro CA, Biral GP, Benassi C, Barbieri GC (1987) Ketamine effects on local cerebral blood flow and metabolism in the rat. J Cereb Blood Flow Metabol 7: 806-811
7. Cold GE (1990) Cerebral blood flow in acute head injury. Acta Neurochir (Wien) [Suppl] 49: 1-64
8. Dawson B, Michenfelder JB, Theye RA (1971) Effects of ketamine on canine cerebral blood flow and metabolism: modification by prior administration of thiopental. Anesth Analg 50: 443-447
9. Doenicke A, Kugler J, Mayer M, Angster R, Hoffmann P (1992) Ketamin-Razemat oder S-(+)-Ketamin und Midazolam. Anaesthesist 41: 610-618
10. Domino EF, Chodoff P, Corssen G (1965) Pharmacologic effects of CI-581, a new dissociative anesthetic in man. Clin Pharmacol Ther 6: 279-291
11. Dragunow M, Goulding M, Faull RLM, Ralph R, Mee E, Frith R (1990) Induction of c-fos mRNA and protein in neurons and glia after traumatic brain injury: pharmacological characterization. Exp Neurol 107: 236-248
12. Eng C, Shapira Y, Lam AM (1992) Ketamine is protective when given 2 but not 4 hours following closed cranial impact in rats. J Neurosurg Anesth 4: 305-308
13. Freye E, Knüfermann V (1994) Keine Hemmung der intestinalen Motilitäl nach Ketamin-/Midazolamnarkose. Anaesthesist 43: 87-91
14. Fukuda S, Murakawa T, Takeshita H, Toda N (1983) Direct effects of ketamine on isolated kanine cerebral and mesenteric arteries. Anaesth Analg 62: 553-558
15. Hoffmann WE, Pelligrino D, Werner C, Kochs E, Albrecht RF. Schulte am Esch J (1992) Ketamine decreases plasma catecholamines and improves outcome from incomplete cerebral ischemia in rats. Anesthesiology 76: 755-762
16. Jennet B. Bond J (1975) Assessment of outcome after severe brain damage. A practical scale. Lancet i: 480-484
17. Johnstone M (1976) The cardiovascular effects of ketamine in man. Anaesthesia 31: 873-882
18. Kochs E, Bischoff P, Rust U, Schulte am Esch J (1990) Plasma-ACTH- und Plasmakortisolspiegel unter Langzeitsedierung mit Midazolam in Kombination mit Opioiden und Ketamin. In: Link J, Eyrich K (eds) Analgesie und Sedierung in der Intensivmedizin. Springer. Berlin Heidelberg New York Tokyo, pp 149-158
19. Lucas JH, Wolf A (1991) In vitro studies of multiple impact injury to mammalian CNS neurons: prevention of perykaryal damage and death by ketamine. Brain Res 543: 181-193
20. Madson JB, Cold GE (1990) The effects of anaesthetics upon cerebral circulation and metabolism. Springer, Berlin Heidelberg New York Tokyo
21. Marshall LF, Marshall SB, Klauber MR, Marjan van Berkum Clark RN (1991) A new classification of head injury based on computerized tomography. J Neurosurg 80: S14-S20
22. Pfenninger E, Dick W, Ahnefeld FW (1985) The influence of ketamine on both normal and raised intracranial pressure of artificially ventilated animals. Eur J Anesthesiol 2: 297-307
23. Pfenninger E, Marx A, Schmitz E, Ahnefeld FW (1987) Wie verhält sich der intrakranielle Druck nach Ketamingabe bei Patienten mit akutem Schädel-Hirn-Trauma? Notfallmedizin 13:472-481
24. Reich DL, Silvay G (1989) Ketamine: an update on the first twenty-five years of clinical experience. Can J Anaesth 36: 186-197
25. Schwedler M, Miletich DJ, Albrecht RF (1982) Cerebral blood flow and metabolism following ketamin administration. Can Anaesth Soc J 29: 222-225
26. Shapira Y, Artru AA, Lam AM (1992) Ketamine decreases cerebral infarct volume and improves neurological outcome following experimental head trauma in rats. Neurosurg Anesthesiol 4: 231-240
27. Shapira Y, Lam EM, Eng CC, Laohaprasit V, Michel M (1994) Therapeutic time window and dose response of the beneficial effects of ketamine in experimental head injury. Stroke 25: 1637-1643
28. Shapiro HM, Wyte SR, Harris AB (1972) Ketamine anesthesia in patients with intracranial pathology. Br J Anaesth 44: 1200-1204
29. Shapiro HM (1975) Intracranial hypertension: therapeutic and anesthetic considerations. Anaesthesiology 43: 445-471
30. Strube PJ, Hallam PL (1986) Ketamine by continuous infusion in status asthmaticus. Anaesthesia 41: 1017-1019
31. Takeshita H, Okuda Y, Sari A (1972) The effects of ketamine on cerebral circulation and metabolism in man. Anaesthesiology 36: 69-75
32. Teasdale G, Jennet B (1974) Assessment of coma and impaired consciousness: a practical scale. Lancet ii: 81-88
33. Thorsen T, Gran L (1980) Ketamine/diazepam infusion. Anaesthesia with special attention to the effect on cerebrospinal fluid pressure and arterial blood pressure. Acta Anaesth Scand 24: 1-5
34. Wengert P, Becker F, Eckart J, Zeravik J (1989) Längerfristige Analgosedierung von Intensivpatienten. Eine vergleichende Untersuchung Midazolam/Ketamin versus Midazolam/Piritramid. In: Ahnefeld FW, Pfenninger E (eds) Ketamin in der Intensiv- und Notfallmedizin. Springer, Berlin Heidelberg New York Tokyo, pp 10-25