메뉴 건너뛰기




Volumn 10, Issue 3, 1996, Pages 269-277

Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: Involvement of potassium channels

Author keywords

Adenosine analogues; Guinea pig; Potassium channels; Relaxation; Trachea

Indexed keywords

3,7 DIMETHYL 1 PROPARGYLXANTHINE; 6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE 5' (N CYCLOPROPYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; CARBACHOL; CROMAKALIM; GLIBENCLAMIDE; IBERIOTOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; RECEPTOR SUBTYPE; VERAPAMIL;

EID: 0029955684     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1996.tb00306.x     Document Type: Article
Times cited : (8)

References (37)
  • 1
    • 0019962588 scopus 로고
    • Contribution of prostaglandins and thromboxanes to the adenosine and ATP-induced contraction of guinea-pig isolated trachea
    • Advenier C, Bidet D, Floch-Saint-Aubin A, Renier A. Contribution of prostaglandins and thromboxanes to the adenosine and ATP-induced contraction of guinea-pig isolated trachea. Br J Pharmacol 1982;77:39-44
    • (1982) Br J Pharmacol , vol.77 , pp. 39-44
    • Advenier, C.1    Bidet, D.2    Floch-Saint-Aubin, A.3    Renier, A.4
  • 2
    • 0023869616 scopus 로고
    • Influence of epithelium on the responsiveness of guinea-pig isolated trachea to adenosine
    • Advenier C, Devillier P, Matran R, Naline E. Influence of epithelium on the responsiveness of guinea-pig isolated trachea to adenosine. Br J Pharmacol 1988;93:295-302
    • (1988) Br J Pharmacol , vol.93 , pp. 295-302
    • Advenier, C.1    Devillier, P.2    Matran, R.3    Naline, E.4
  • 3
    • 85047677008 scopus 로고
    • ATP sensitive potassium channels are involved in adenosine A2-receptor mediated coronary vasodilatation in the dog
    • Akatsuka Y, Egashira K, Katsuda Y, Narishige T, Ueno H, Shimokawa H, Takeshita A. ATP sensitive potassium channels are involved in adenosine A2-receptor mediated coronary vasodilatation in the dog. Cardiovasc Res 1994;28:906-11
    • (1994) Cardiovasc Res , vol.28 , pp. 906-911
    • Akatsuka, Y.1    Egashira, K.2    Katsuda, Y.3    Narishige, T.4    Ueno, H.5    Shimokawa, H.6    Takeshita, A.7
  • 4
    • 0028271451 scopus 로고
    • Adenosine receptor-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbit model
    • Ali S, Mustafa SJ, Metzger WJ. Adenosine receptor-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbit model. Am J Physiol 1994;266:L271-7
    • (1994) Am J Physiol , vol.266
    • Ali, S.1    Mustafa, S.J.2    Metzger, W.J.3
  • 5
    • 0026079557 scopus 로고
    • Relaxant effects of adenosine analogs on guinea-pig trachea in vitro: Xanthine-sensitive and xantine-insensitive mechanisms
    • Brackett LE, Daly JW. Relaxant effects of adenosine analogs on guinea-pig trachea in vitro: xanthine-sensitive and xantine-insensitive mechanisms. J Pharmacol Exp Ther 1991; 257:205-13
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 205-213
    • Brackett, L.E.1    Daly, J.W.2
  • 6
    • 0020001309 scopus 로고
    • Evidence for an A2/Ra adenosine receptor in the guinea-pig trachea
    • Brown CM, Collis MG. Evidence for an A2/Ra adenosine receptor in the guinea-pig trachea. Br J Pharmacol 1982; 76:381-7
    • (1982) Br J Pharmacol , vol.76 , pp. 381-387
    • Brown, C.M.1    Collis, M.G.2
  • 9
    • 0024820687 scopus 로고
    • Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1- and A2-receptors in isolated tissues from guinea-pigs
    • Collis MG, Stoggall SM, Martin FM. Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1- and A2-receptors in isolated tissues from guinea-pigs. Br J Pharmacol 1989;97:1274-8
    • (1989) Br J Pharmacol , vol.97 , pp. 1274-1278
    • Collis, M.G.1    Stoggall, S.M.2    Martin, F.M.3
  • 10
    • 0028921547 scopus 로고
    • Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40
    • Cook SJ, Archer K, Martin A et al. Further analysis of the mechanisms underlying the tracheal relaxant action of SCA40. Br J Pharmacol 1995;114:143-51
    • (1995) Br J Pharmacol , vol.114 , pp. 143-151
    • Cook, S.J.1    Archer, K.2    Martin, A.3
  • 11
    • 0020655642 scopus 로고
    • Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects
    • Cushley MJ, Tattersfield AE, Holgate ST. Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 1983;15:161-5
    • (1983) Br J Clin Pharmacol , vol.15 , pp. 161-165
    • Cushley, M.J.1    Tattersfield, A.E.2    Holgate, S.T.3
  • 12
    • 0021350144 scopus 로고
    • Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline
    • Cushley MJ, Tattersfield AE, Holgate ST. Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline. Am Rev Respir Dis 1984;129:380-4
    • (1984) Am Rev Respir Dis , vol.129 , pp. 380-384
    • Cushley, M.J.1    Tattersfield, A.E.2    Holgate, S.T.3
  • 13
    • 0020025294 scopus 로고
    • Adenosine receptors: Targets for future drugs
    • Daly JW. Adenosine receptors: targets for future drugs. J Med Chem 1982;25:197-207
    • (1982) J Med Chem , vol.25 , pp. 197-207
    • Daly, J.W.1
  • 14
    • 0022552236 scopus 로고
    • Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea
    • Darmani NA, Broadley KJ. Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea. Eur J Pharmacol 1986;125:353-62
    • (1986) Eur J Pharmacol , vol.125 , pp. 353-362
    • Darmani, N.A.1    Broadley, K.J.2
  • 16
    • 0017124553 scopus 로고
    • Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle
    • Farmer JB, Farrar DG. Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle. J Pharm Pharmacol 1976;28:748-52
    • (1976) J Pharm Pharmacol , vol.28 , pp. 748-752
    • Farmer, J.B.1    Farrar, D.G.2
  • 17
    • 0023740858 scopus 로고
    • Adenosine receptor-mediated contraction and relaxation of guinea-pig isolated tracheal smooth muscle: Effects of adenosine antagonists
    • Farmer SG, Canning BJ, Wilkins DE. Adenosine receptor-mediated contraction and relaxation of guinea-pig isolated tracheal smooth muscle: effects of adenosine antagonists. Br J Pharmacol 1988;95:371-8
    • (1988) Br J Pharmacol , vol.95 , pp. 371-378
    • Farmer, S.G.1    Canning, B.J.2    Wilkins, D.E.3
  • 18
    • 0027513240 scopus 로고
    • The cardiovascular effects of selective adenosine A1- An A2-receptor agonists in the pithed rat: No role for glibenclamide-sensitive potassium channels
    • Fozard JR, Carruthers AM, The cardiovascular effects of selective adenosine A1- an A2-receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels. Naunyn Schmiedeberg's Arch Pharmacol 1993;347:192-6
    • (1993) Naunyn Schmiedeberg's Arch Pharmacol , vol.347 , pp. 192-196
    • Fozard, J.R.1    Carruthers, A.M.2
  • 19
    • 0018642309 scopus 로고
    • On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors
    • Fredholm BB, Brodin K, Strandberg IC. On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors. Acta Pharmacol Toxicol 1979;45:336-44
    • (1979) Acta Pharmacol Toxicol , vol.45 , pp. 336-344
    • Fredholm, B.B.1    Brodin, K.2    Strandberg, I.C.3
  • 20
    • 0025299607 scopus 로고
    • Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus
    • Galvez A, Gimenez-Gallego G, Reuben JP, Roy-Contancin L, Feigenbaum P, Kaczorowsky GJ, Garcia ML. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J Biol Chem 1990;265:11083-90
    • (1990) J Biol Chem , vol.265 , pp. 11083-11090
    • Galvez, A.1    Gimenez-Gallego, G.2    Reuben, J.P.3    Roy-Contancin, L.4    Feigenbaum, P.5    Kaczorowsky, G.J.6    Garcia, M.L.7
  • 21
    • 0023161502 scopus 로고
    • Evidence for A1- and A2-adenosine receptors in guinea-pig trachea
    • Ghai G, Zimmerman MB, Hopkins MF. Evidence for A1- and A2-adenosine receptors in guinea-pig trachea. Life Sci 1987;41:1215-24
    • (1987) Life Sci , vol.41 , pp. 1215-1224
    • Ghai, G.1    Zimmerman, M.B.2    Hopkins, M.F.3
  • 23
    • 0020404878 scopus 로고
    • Effects on tracheal smooth muscle of adenosine and methylxanthines, and their interaction
    • Karlsson JA, Kjellin G, Persson CGA. Effects on tracheal smooth muscle of adenosine and methylxanthines, and their interaction. J Pharm Pharmacol 1982;34:788-93
    • (1982) J Pharm Pharmacol , vol.34 , pp. 788-793
    • Karlsson, J.A.1    Kjellin, G.2    Persson, C.G.A.3
  • 24
    • 0024124482 scopus 로고
    • Adenosine-induced bronchoconstriction in the guinea-pig isolated lung: Interaction with theophylline and enprofylline
    • Kröll F, Karlsson JA, Persson CGA. Adenosine-induced bronchoconstriction in the guinea-pig isolated lung: interaction with theophylline and enprofylline. Pulm Pharmacol 1988;1:85-92
    • (1988) Pulm Pharmacol , vol.1 , pp. 85-92
    • Kröll, F.1    Karlsson, J.A.2    Persson, C.G.A.3
  • 27
    • 0025315004 scopus 로고
    • 2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea pigs
    • Manzini S, Ballati L. 2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea pigs. Br J Pharmacol 1990;100:251-6
    • (1990) Br J Pharmacol , vol.100 , pp. 251-256
    • Manzini, S.1    Ballati, L.2
  • 28
    • 0026608767 scopus 로고
    • Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: Involvement of potassium channels
    • Merkel LA, Lappe RW, Rivera LM, Cox BF, Perrone MH. Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: involvement of potassium channels. J Pharmacol Exp Ther 1992;260: 437-43
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 437-443
    • Merkel, L.A.1    Lappe, R.W.2    Rivera, L.M.3    Cox, B.F.4    Perrone, M.H.5
  • 30
    • 0027939241 scopus 로고
    • Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists
    • Niiya K, Uchida S, Tsuji T, Olsson RA. Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists. J Pharmacol Exp Ther 1994;271:14-9
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 14-19
    • Niiya, K.1    Uchida, S.2    Tsuji, T.3    Olsson, R.A.4
  • 31
    • 0027416633 scopus 로고
    • + channels in the sustained coronary vasodilator response to adenosine in dogs
    • + channels in the sustained coronary vasodilator response to adenosine in dogs. Eur J Pharmacol 1993;231:183-9
    • (1993) Eur J Pharmacol , vol.231 , pp. 183-189
    • Orito, K.1    Satoh, K.2    Taira, N.3
  • 32
    • 0023608812 scopus 로고
    • An animal model for adenosine-induced bronchoconstriction
    • Pauwels RA, Van Der Straeten ME. An animal model for adenosine-induced bronchoconstriction. Am Rev Respir Dis 1987;136:374-8
    • (1987) Am Rev Respir Dis , vol.136 , pp. 374-378
    • Pauwels, R.A.1    Van Der Straeten, M.E.2
  • 34
    • 0026683126 scopus 로고
    • Adenosine-induced bronchoconstriction of isolated lung and trachea from sensitized guinea-pigs
    • Thorne JR, Broadley KJ. Adenosine-induced bronchoconstriction of isolated lung and trachea from sensitized guinea-pigs. Br J Pharmacol 1992;106:978-85
    • (1992) Br J Pharmacol , vol.106 , pp. 978-985
    • Thorne, J.R.1    Broadley, K.J.2
  • 35
    • 0018634064 scopus 로고
    • Adenosine regulates, via two different types of receptors, the accumulation of cyclic AMP in cultured cells
    • Van Calker D, Müller M, Hamprecht B. Adenosine regulates, via two different types of receptors, the accumulation of cyclic AMP in cultured cells. J Neurochem 1979;33: 999-1005
    • (1979) J Neurochem , vol.33 , pp. 999-1005
    • Van Calker, D.1    Müller, M.2    Hamprecht, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.