Palladium-catalyzed cross coupling reactions of oxazol-2-ylzinc chloride derivatives

Synthesis

Volumn , Issue 5, 1996, Pages 583-585

  Anderson, Benjamin A ^a   Harn, Nancy K ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

cross coupling; oxazole; palladium catalysts; zinc chloride

Indexed keywords

OXAZOLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029955627     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1996-4274     Document Type: Article

References (20)

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14. Crowe, E.; Hossner, F.; Hughes, M. J. Tetrahedron 1995, 51, 8889.
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16. (b) For lithiation of substituted oxazole derivatives, see: Whitney, S. E.; Rickborn, B. J. J. Org. Chem. 1991, 56, 3058, and references cited therein.
17. Negishi, E.; Takahashi, T.; Akiyoshi, K. J. Chem. Soc., Chem. Commun. 1986, 1338.
18. The indicated yields represent percent conversion. Yields cited in all Tables are for isolated products.
19. Bell, A. S.; Roberts, D. A.; Ruddock, K. S. Tetrahedron Lett. 1988, 29, 5013.
20. 3) to give 8e in 44% yield.