Sequential action of factors involved in natural competence for transformation of Neisseria gonorrhoeae

FEMS Microbiology Letters

Volumn 137, Issue 2-3, 1996, Pages 159-164

  Facius, Dirk ^a   Fussenegger, Martin ^a   Meyer, Thomas F ^a  

^a MAX PLANCK INST FÜR BIOLOGIE   (Germany)

Author keywords

DNA uptake; gene transfer; horizontal genetic exchange; Neisseria gonorrhoeae; recombination; transformation competence

Indexed keywords

ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DNA RECOMBINATION; DNA SEQUENCE; DNA TRANSFER; GENE TRANSFER; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029955225     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(96)00044-4     Document Type: Article

References (28)

1. Sparling, P.F. (1966) Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance. J. Bacteriol. 92, 1364-1369.
2. Frosch, M. and Meyer, T.F. (1992) Transformation-mediated exchange of virulence determinants by co-cultivation of pathogenic Neisseria. FEMS Microbiol. Lett. 100, 3435-3439.
3. Spratt, B.G., Bowler, L.D., Zhang, Q.Y., Zhon, J. and Smith J.M. (1992) Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species. J. Mol. Evol. 34, 115-125.
4. Halter, R., Pohlner, J. and Meyer, T.F. (1989) Mosaic-like organisation of IgA protease genes in Neisseria gonorrhoeae generated by horizontal genetic exchange in vivo. EMBO J. 8, 2737-2744.
5. Feavers, I.M., Heath, A.B., Bygraves, J.A. and Maiden, M.C.J. (1992) Role of horizontal genetic exchange in the antigenic variation of the class 1 outer membrane protein of Neisseria meningitidis. Mol. Microbiol. 6, 489-495.
6. Maynard Smith, J., Smith, N.H., O'Rourke, M. and Spratt, B.G. (1993) How clonal are bacteria? Proc. Natl. Acad. Sci. USA 90, 4384-4388.
7. Seifert, H.S., Ajioka, R.S., Marchal, C., Sparling, P.F. and So, M. (1988) DNA transformation leads to pilin antigenic variation in Neisseria gonorrhoeae. Nature 336, 392-395.
8. Gibbs, C.P., Reinmann, B.-Y., Schultz, E., Kaufmann, A., Haas, R. and Meyer T.F. (1989) Reassortment of pilin genes in Neisseria gonorrhoeae occurs by two distinct mechanisms. Nature 338, 651-652.
9. Meyer, T.F., Pohlner, J. and van Putten, J.P.M. (1994) Biology of the pathogenic Neisseriae. Curr. Topics Microbiol. Immunol. 192, 283-317.
10. Biswas, G.D., Lacks, S.A. and Sparling, P.F. (1989) Transformation-deficient mutants of piliated Neisseria gonorrhoeae. J. Bacteriol. 171, 657-664.
11. Lauer, P., Albertson, N.H. and Koomey, M. (1993) Conservation of genes encoding components of a type IV pilus assembly/two-step export pathway in Neisseria gonorrhoeae. Mol. Microbiol. 8, 357-368.
12. Koomey, M., Fox, R., Brossay, L. and Hebert, J. (1994) The gonococcal PilT protein plays an essential role in pilus-associated phenotypes of twitching motility and natural competence for transformation. In: Abstracts of the Ninth International Pathogenic Neisseria Conference, Winchester, p. 64.
13. Rudel, T., Facius, D., Barten, R., Scheuerpflug, I., Nonnenbacher, E. and Meyer, T.F. (1995) Role of pili and the phase variable PiIC protein in natural competence for transformation of Neisseria gonorrhoeae. Proc. Natl. Acad. Sci. USA 92, 7986-7990..
14. Goodman, S.D. and Scocca, J.J. (1988) Identification and arrangement of the DNA sequence recognized in specific transformation of Neisseria gonorrhoeae. Proc. Natl. Acad. Sci. USA 85, 6982-6986.
15. Facius, D. and Meyer, T.F. (1993) A novel determinant (comA) essential for natural transformation competence in Neisseria gonorrhoeae and the effect of a comA mutant defect on pilin variation. Mol. Microbiol. 14, 699-712.
16. Fussenegger, M., Facius, D., Maier, J. and Meyer, T.F. (1996) A novel peptidoglycan-associated lipoprotein (ComL) functions in natural transformation competence of Neisseria gonorrhoeae. Mol. Microbiol. (in press).
17. Fussenegger, M., Kahrs, A., Facius, D. and Meyer, T.F. (1996) Tetrapac (tpc), a novel genotype of Neisseria gonorrhoeae affecting epithelial cell invasion, natural transformation competence and cell separation. Mol. Microbiol. (in press).
18. Koomey, J.M., Gotschlich, E.C., Robbins, K., Bergström, S. and Swanson, J. (1987) Effects of recA mutations on pilus antigenic variation and phase transitions in Neisseria gonorrhoeae. Genetics 117, 391-398.
19. Biswas, G.D., Burnstein, K.L. and Sparling, P.F. (1986) Linearization of donor DNA during plasmid transformation in Neisseria gonorrhoeae. J. Bacteriol. 168, 756-761.
20. Meyer, T.F., Billyard, E., Haas, R., Störzbach, S. and So, M. (1984) Pilus gene of Neisseria gonorrhoeae: chromosomal organization and DNA sequence. Proc. Natl. Acad. Sci. USA 81, 6110-6114.
21. Rudel, T., Boxberger, H.J. and Meyer, T.F. (1995) Pilus biogenesis and epithelial cell adherence of Neisseria gonorrhoeae pilC double knock-out mutants. Mol. Microbiol. 17, 1057-1071.
22. Haas, R., Kahrs, A.F., Facius, D., Allmeier, H., Schmitt, R. and Meyer T.F. (1993) TnMax - a versatile mini-transposon for the analysis of cloned genes and shuttle mutagenesis. Gene 130, 23-31.
23. Jonnson, A.-B., Nyberg, G. and Normark, S. (1991) Phase variation of gonococcal pili by frame shift mutation in pilC, a novel gene for pilus assembly. EMBO J. 10, 477-488.
24. Tonjum, T., Freitag, N.E., Namork, E. and Koomey, M. (1995) Identification and characterization of pilG, a highly conserved pilus-assembly gene in pathogenic Neisseria. Mol. Microbiol. 16, 451-464.
25. Freitag, N.E., Seifert, H.S. and Koomey, M. (1995) Characterization of the pilF-pilD pilus-assembly locus of Neisseria gonorrrhoeae. Mol. Microbiol. 16, 575-586.
26. Rudel, T., Scheuerpflug, I. and Meyer, T.F. (1995) Neisseria PilC protein identified as type 4 pilus tip-located adhesin. Nature 373, 357-359.
27. Stein, C.D., Chien, R. and Seifert, H.S. (1992) Construction of a Neisseria gonorrhoeae MS 11 derivative deficient in NgoMI restriction and modification. J. Bacteriol. 174, 4899-4906.
28. Hobbs, M. and Mattick, J.S. (1993) Common components in the assembly of type 4 fimbriae. DNA transfer systems, filamentous phage and protein-secretion apparatus: a general system for the formation of surface-associated protein complexes. Mol. Microbiol. 10, 233-243.