p53 inhibits JC virus DNA replication in vivo and interacts with JC virus large T-antigen

Virology

Volumn 219, Issue 1, 1996, Pages 237-246

  Staib, Caroline ^a   Pesch, Jürgen ^a   Gerwig, Rainer ^a   Gerber, Josef Karl ^a   Brehm, Ursula ^a   Stangl, Adelgunde ^a   Grummt, Friedrich ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; VIRUS LARGE T ANTIGEN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA REPLICATION; GENE EXPRESSION; HUMAN; HUMAN CELL; JC VIRUS; PRIORITY JOURNAL; VIRUS INHIBITION;

ANIMALIA; JC VIRUS; MURINAE;

EID: 0029955178     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0241     Document Type: Article

References (50)

1. Bargonetti, J., Reynosdottir, I., Friedman, P., and Prives, C. (1992). Sitespecific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev. 6, 1886-1898.
2. Berger, J. R., and Concha, M. (1995). Progressive multifocal leukoencephalopathy: The evolution of a disease once considered rare. J Neurovirol. 1, 5-18.
3. Bollag, B., Chuke, W. F., and Frisque, R. J. (1989). Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: Identification of sequences important for efficient transformation. J. Virol. 63, 863-872.
4. Borowiec, J. A., Dean, F. B., Bullock, P. A., and Hurwitz, J. (1990). Binding and unwinding - How T antigen engages the SV40 origin of DNA replication. Cell 60, 181-184.
5. Braithwaite, A. W., Stürzbecher, H.-W., Addison, C., Palmer, C., Rudge, K., and Jenkins, J. R. (1987). Mouse p53 inhibits SV40 origin-dependent DNA replication. Nature 329, 458-460.
6. Diller, L., Kassel, J., Nelson, C. E., Gryka, M. A., Litwak, G., Gebhardt, M., Bressac, B., Ozturk, M., Baker, S. J., Vogelstein, B., and Friend, S. H. (1990). p53 functions as a cell cycle control protein in osteosarcomas. Mol. Cell. Biol. 10, 5772-5781.
7. Donehower, L. A., and Bradley, A. (1993). The tumor suppressor p53. Biochem. Biophys. Acta 1155, 181-205.
8. Dutta, A., Ruppert, J. M., Aster, J. C., and Winchester, E. (1993). Inhibition of DNA replication factor RPA by p53. Nature 365, 79-82.
9. Eliyahu, D., Michalovitz, D., Eliyahu, S., Pinhasi-Kimhi, O., and Oren, M. (1989). Wild-type p53 can inhibit oncogene-mediated focus formation. Proc. Natl. Acad. Sci. USA 86, 8763-8767.
10. Farmer, G. E., Bargonetti, J., Zhu, H., Friedman, P. N., Prywes, R., and Prives, C. (1992). Wild type p53 activates transcription in vitro. Nature 358, 83-86.
11. Feigenbaum, L., Khalili, K., Major, E., and Khoury, G. (1987). Regulation of the host range of human papovavirus JC. Proc. Natl. Acad. Sci. USA 84, 3695-3668.
12. Friedman, P. N., Kern, S. E., Vogelstein, B., and Prives, C. (1990). Wildtype, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen. Proc. Natl. Acad. Sci. USA 87, 9275-9279.
13. Frisque, R., Bream, G., and Canella, M. (1984). Human polyomavirus JC virus genome. J. Virol. 51, 458-469.
14. Funk, W. D., Pak, D. T., Karas, R. H., Wright, W. E., and Shay, J. W. (1992). A transcriptionally active DNA-binding site for human p53 protein complexes. Mol. Cell. Biol. 12, 2866-2871.
15. Ginsberg, D., Mechta, F., Yaniv, M., and Oren, M. (1991). Wild-type p53 can down-modulate the activity of various promoters. Proc. Natl. Acad. Sci. USA 88, 9979-9983.
16. Gannon, J. V., and Lane, D. P. (1987). p53 and DNA polymerase a compete for binding to SV40 T antigen. Nature 329, 456-458.
17. Green, S., Issemann, I., and Sheer, E. (1988). A versatile in vivo and in vitro expression vector for protein engineering. Nucleic Acids Res. 16, 369.
18. He, Z., Brinton, B. T., Greenblatt, J., Hassel, J. A., and Ingles, C. J. (1993). The transactivator proteins VP16 and GAL4 bind replication factor A. Cell 73, 1223-1232.
19. Hirt, B. (1967). Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol. 26, 365-369.
20. Jenkins, J. R., Chamukov, P., Addison, C., Stürzbecher, H.-W., and WadeEvans, A. (1988). Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen. J. Virol. 62, 3903-3906.
21. Kenney, S., Natarajan, V., Strika, V., Khoury, G., and Salzman, N. P. (1984). JC virus enhancer-promoter active in human brain cells. Science 226, 1337-1339.
22. Kienzle, H., Baack, M., and Knippers, R. (1989). Effects of the cellular p53 protein on simian-virus-40-T-antigen-catalyzed DNA unwinding in vitro. Eur. J. Biochem. 184, 181-186.
23. Lane, D. P., and Benchimol, S. (1990). p53: Oncogens or anti-oncogene? Genes Dev. 4, 1-8.
24. Levine, A. J., Momand, J., and Finlay, C. A. (1991). The p53 tumor suppressor gene. Nature 351, 453-456.
25. Li, R., and Botchan, M. R. (1993). The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication. Cell 73, 1207-1221.
26. Lin, J.-Y., and Simmons, D. T. (1991). The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40. J. Virol. 65, 6447-6453.
27. Ludlow, J. W. (1993). Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB J. 7, 866-871.
28. Lynch, K. J., and Frisque, R. J. (1990). Identification of critical elements within the JC virus DNA replication origin. J. Virol. 64, 5812-5822.
29. Major, E. O., and Traub, R. G. (1986). JC virus T protein during productive infection in human fetal brain and kidney cells. Virology 148, 221-225.
30. Major, E. O., Vacante, D. A., Traub, R. G., London, W. T., and Sever, J. L. (1987). Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties. J. Virol. 61, 1435-1441.
31. Martinez, J., Georgoff, I., Martinez, J., and Levine, A. J. (1991). Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev. 5, 151-159.
32. Mercer, W. E., Shields, M. T., Amin, M., Sauve, J., Apella, E., Romano, J., and Ullrich, S. J. (1990). Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. Proc. Natl. Acad. Sci. USA 87, 6166-6170.
33. Michalovitz, D., Halevy, O., and Oren, M. (1990). Conditional inhibition of transformation and cell proliferation by a temperature-sensitive mutant of p53. Cell 62, 671-680.
34. Miyamoto, N., Kihara, E., Inada, T., Katsura, S., and Murakami, Y. (1990). Primate's p53 inhibits SV40 DNA replication in vitro. Biochem. Biophys. Res. Commun. 168, 604-608.
35. Prives, C., and Manfredi, J. J. (1993). The p53 tumor suppressor protein: meeting review. Genes Dev. 7, 529-534.
36. Puppert, M. J., and Stillman, B. (1993). Analysis of a protein-binding domain of p53. Mol. Cell. Biol. 13, 3811-3820.
37. Shaulian, E., Zauberman, A., Ginsberg, D., and Oren, M. (1992). Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol. 12, 5581-5592.
38. Sock, E., Wegner, M., and Grummt, F. (1991). DNA replication of human polyomavirus JC is stimulated by NF-1 in vivo. Virology 182, 298-308.
39. Sock, E., Wegner, M., Fortunato, E. A., and Grummt, F. (1993). Large T-antigen and sequences within the regulatory region of JC virus both contribute to the features of JC virus DNA replication. Virology 197, 537-548.
40. Stenger, J. E., Tegtmeyer, P., Mayr, G. A., Reed, M., Wang, Y., Wang, P., Hough, P. V. C., and Mastrangelo, I. A. (1994). p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J. 13, 6011-6020.
41. Stürzbecher, H.-W., Brain, R., Maimets, T., Addison, C., Rudge, K., and Jenkins, J. R. (1988). Mouse p53 blocks SV40 DNA replication in vitro and downregulates T antigen helicase activity. Oncogene 3, 405-413.
42. Stürzbecher, H.-W., Brain, R., Addison, C., Rudge, K., Remm, M., Grimaldi, M., Keenan, E., and Jenkins, J. R. (1992). A C-terminal α-helix plus basic region motif is the major structural determinant of p53 tetramerization. Oncogene 7, 1513-1523.
43. Subler, M. A., Martin, D. W., and Deb, S. (1994). Overlapping domains on the p53 protein regulate its transcriptional activation and repression functions. Oncogene 9, 1351-1359.
44. Tan, T.-H., Wallis, J., and Levine, A. J. (1986). Identification of the p53 protein domain involved in formation of the simian virus 40 large T antigen-p53 protein complex. J. Virol. 59, 574-583.
45. Trowbridge, P., and Frisque, R. J. (1993). Analysis of G418-selected Rat2 cells containing prototype, variant, mutant, and chimeric JC virus and SV40 virus genomes. Virology 196, 458-474.
46. von der Weth, A., and Deppert, W. (1993). Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells. J. Virol. 67, 886-893.
47. Walker, D. L., and Frisque, R. J. (1986). The biology and molecular biology of JC virus. In "The Papovaviridae: The Polyomaviruses" (N. P. Salzman, Ed.), Vol. I, pp. 327-377. Plenum, New York.
48. Wang, E. H., Friedman, P. N., and Prives, C. (1989). The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV 40 large T antigen. Cell 57, 379-392.
49. Wilcock, D., and Lane, D. P. (1991). Localization of p53, retinoblastoma and host replication proteins as sites of viral replication in herpesinfected cells. Nature 349, 429-431.
50. Zhu, J., Rice, P. W., Gorsch, L., Abate, M., and Cole, C. N. (1991). The ability of SV40 large T antigen to immortalize primary mouse embryo fibroplasts co-segregates with its ability to bind p53. J Virol. 65, 6872-6880.