The majority of extrathymic T cells in the liver have the phenotype of memory T cells

Biomedical Research

Volumn 17, Issue 2, 1996, Pages 149-159

  Nakayama, Mauro ^a   Ohtsuka, Kazuo ^a   Sato, Kazunari ^a   Hasegawa, Katsuhiko ^a   Yamagiwa, Satoshi ^a   Sakai, Kunio ^a   Abo, Toru ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CELL ADHESION MOLECULE; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR; L SELECTIN; MONOCLONAL ANTIBODY; OVALBUMIN;

AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LIVER; LYMPHOCYTE SUBPOPULATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALIA;

EID: 0029954851     PISSN: 03886107     EISSN: None     Source Type: Journal    
DOI: 10.2220/biomedres.17.149     Document Type: Article

References (39)

1. ABO T., OHTEKI T., SEKI S., KOYAMADA N., YOSHIKAI Y., MASUDA T., RIKHSHI H. and KUMAGAI K. (1991) The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. J. Exp. Med. 174, 417-424
2. ALDHOUS M. C., RAAB G. M., DOHERTY K. V., MOK J. Y. Q., BIRD A. G. and FROEBEL K. S. (1994) Age-related changes of memory, activation, and cytotoxic markers on CD4 and CD8 cells in children. J. Clin. Immunol. 14, 289-298
3. -, on intermediate TCR cells in the liver and the modulatin of their adhesion by hyaluronic acid. Immunology 84, 64-71
4. - single-positive thymocyte subpopulation that expresses the highly skewed T-cell antigen receptor Vβ family. Proc. Natl. Acad. Sci. USA 89, 6506-6510
5. BELL E. B. and SPARSHOTT S. M. (1990) Interconversion of CD45R subsets of CD4 T cells in vivo. Nature 348, 163-166
6. BEVERLEY P. C. L. (1990) Is T-cell memory maintained by crossreactive stimulation? Immunol. Today 11, 203-205
7. BIRKELAND M. L., JOHNSON P., TROWBRIDGE I. S. and PURE E. (1989) Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc. Natl. Acad. Sci. USA 86, 6734-6738
8. BRADLEY L. M., WATSON S. R. and SWAIN S. L. (1994) Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J. Exp. Med. 180, 2401-2406
9. CHARBONNEAU H., TONKS N. K., WALSH K. A. and FISCHER E. H. (1988) The leukocyte common antigen (CD45): A putative receptor-linked protein tyrosine phosphatase. Proc. Natl. Acad. Sci. USA 85, 7182-7186
10. + T cells from aged mice display functional and phenotypic characteristics of memory cells. Int. Immunol. 6, 1227-1234
11. ENGWERDA C. R., HANDWERGER B. S. and Fox B. S. (1994) Aged T cells are hyporesponsive to costimulation mediated by CD28. J. Immunol. 152, 3740-3747
12. + lymphocytes: Mouse strain polymorphism and different responses to distinct antigens. Cell. Immunol. 148, 269-282
13. + cells in the thymus. Int. Immunol. 4, 1303-1311
14. GRAY D. (1993) Immunological memory. Annu. Rev. Immunol. 11, 49-77
15. GRUBER M. F., WEBB D. S. A. and GERRARD T. L. (1992) Stimulation of human monocytes via CD45, CD44, and LFA-3 triggers macrophage-colony-stimulating factor production. Synergism with lipopolysaccharide and IL-1β. J. Immunol. 148, 1113-1118
16. IIAI T., WATANABE H., SEKI S., SUGIURA K., HIROKAWA K., UTSUYAMA M., TAKAHASHI-IWANAGA H., IWANAGA T., OHTEKI T. and ABO T. (1992) Ontogeny and development of extrathymic T cells in mouse liver. Immunology 77, 556-563
17. JANEWAY C. A. JR. (1992) The T cell receptor as a multi-component signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10, 645-674
18. KAWACHI Y., IIAI T., MORODA T., WATANABE T., HAGA M., WATANABE H., HATAKEYAMA K. and ABO T. (1994) Profound suppression of the differentiation and functions of intermediate TCR cells in the liver of mice with liver injury induced by carbon tetrachloride. Biomedical Res. 15, 325-336
19. MACKAY C. R. (1991) T-cell memory: the connection between function, phenotype and migration pathways. Immunol. Today 12, 189-192
20. + cells in the liver of mice. J. Exp. Med. 180, 699-704
21. OHTEKI T., OKUYAMA R., SEKI S., ABO T., SUGIURA K., KUSUMI A., OHMORI T., WATANABE H. and KUMAGAI K. (1992) Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J. Immunol. 149, 1562-1570
22. OHTSUKA K., HASEGAWA K., SATO K., ARAI K., WATANABE H., ASAKURA H. and ABO T. (1994) A similar expression pattern of adhesion molecules between intermediate TCR cells in the liver and intraepithelial lymphocytes in the intestine. Microbiol. Immunol. 38, 677-683
23. OHTSUKA K., IIAI T., WATANABE H., TANAKA T., MIYASAKA M., SATO K., ASAKURA H. and ABO T. (1994) Similarities and differences between extrathymic T cells residing in mouse liver and intestine. Cell. Immunol. 153, 52-66
24. OHTSUKA K., SATO K., WATANABE H., KIMURA M., ASAKURA H. and ABO T. (1995) Unique order of the lymphocyte subset induction in the liver and intestine of mice during Listeria monocytogenes infection. Cell. Immunol. 161, 112-124
25. + T cells contain cells with high levels of lymphocyte function-associated antigen-1 expression, a phenotype of primed T cells. J. Immunol. 150, 429-437
26. OKUYAMA R., ABO T., SEKI S., OHTEKI T., SUGIURA K., KUSUMI A. and KUMAGAI K. (1992) Estrogen administration activates extrathymic T cell differentiation in the liver. J. Exp. Med. 175, 661-669
27. PAGANELLI R., CHERCHI M., SCALA E., MAGGI E., CARBONARI M., FERRANTI G., DELL'ANNA L., PACHI A. and FIORILLI M. (1994) Activated and "memory" phenotype of circulating T lymphocytes in intrauterine life. Cell. Immunol. 155, 486-492
28. + lymphocytes in patients with ataxia-telangiectasia. J. Clin. Immunol. 12, 84-91
29. PILARSKI L. M., GILLITZER R., ZOLA H., SHORTMAN K. and SCOLLAY R. (1989) Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD45 (T200). Eur. J. Immunol. 19, 589-597
30. + T cells in patients with chronic type C hepatitis after treatment with α-interferon. Int. Hepatol. Com. 2, 398-402
31. SARAWAR S. R., SPARSHOTT S. M., SUTTON P., YANG C.-P., HUTCHINSON I. V. and BELL E. B. (1993) Rapid re-expression of CD45RC on rat CD4 T cells in vitro correlates with a change in function. Eur. J. Immunol. 23, 103-107
32. SARAWAR S. R., YANG C.-P. and BELL E. B. (1991) T-cell receptor-bearing cells from athymic nude rats respond to alloantigen in vitro but are defective in vivo. Immunology 73, 334-341
33. + T cells. J. Immunol. 153, 637-646
34. SPARSHOTT S. M. and BELL E. B. (1994) Membrane CD45R isoform exchange on CD4 T cells is rapid, frequent and dynamic in vivo. Eur. J. Immunol. 24, 2573-2578
35. + T cells in patients with malignancy. Clin. Exp. Immunol. 97, 522-527
36. t. Cell 41, 83-93
37. TSUCHIDA M., IIAI T., WATANABE H. and ABO T. (1992) Relative resistance of intermediate TCR cells to anti-CD3 mAb in mice in vivo and their partial functional characterization. Cell. Immunol. 145, 78-90
38. WATANABE H., IIAI T., KIMURA M., OHTSUKA K., TANAKA T., MIYASAKA M., TSUCHIDA M., HANAWA H. and ABO T. (1993) Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression. Cell. Immunol. 149, 331-342
39. WANATABE H., OHTSUKA K., KIMURA M., IKARASHI Y., OHMORI K., KUSUMI A., OHTEKI T., SEKI S. and ABO T. (1992) Details of an isolation method for hepatic lymphocytes in mice. J. Immunol. Methods 146, 145-154